Patents by Inventor Pascal JONKHEIJM

Pascal JONKHEIJM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Functionalization of biopolymers with growth factor-binding peptides
    Patent number: 12275803
    Abstract: The disclosure relates to a biopolymer that is functionalized with a peptide, preferably a growth factor-binding peptide. The disclosure further relates to a device comprising a functionalized biopolymer, to methods for treatment of a tissue pathology in a subject using a device according to the disclosure, to methods for coupling peptides to carbonyl groups of a biopolymer, and to a use of oxygen plasma for coupling a peptide to carbonyl groups of a biopolymer.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: April 15, 2025
    Assignee: Universiteit Twente
    Inventors: João Francisco Ribeiro Pereira Simões Crispim, Pascal Jonkheijm, Daniël Bart Frederik Saris
  • FUNCTIONALIZATION OF BIOPOLYMERS WITH GROWTH FACTOR-BINDING PEPTIDES
    Publication number: 20200095341
    Abstract: The disclosure relates to a biopolymer that is functionalized with a peptide, preferably a growth factor-binding peptide. The disclosure further relates to a device comprising a functionalized biopolymer, to methods for treatment of a tissue pathology in a subject using a device according to the disclosure, to methods for coupling peptides to carbonyl groups of a biopolymer, and to a use of oxygen plasma for coupling a peptide to carbonyl groups of a biopolymer.
    Type: Application
    Filed: November 30, 2017
    Publication date: March 26, 2020
    Inventors: João Francisco Ribeiro Pereira Simões Crispim, Pascal Jonkheijm, Daniël Bart Frederik Saris
  • Stamp for making a microarray of biomolecules
    Patent number: 9636653
    Abstract: A stamp for making a microarray of biomolecules, wherein the stamp has a stamp body having a stamping surface for stamping the biomolecules onto a substrate, a plurality of reservoirs for liquids having the biomolecules, wherein each of the reservoirs has a bottom wall and a plurality of channels extending between each of the bottom wall and the stamping surface, wherein each of the reservoirs and the channels has a macroporous hydrogel and wherein the stamping surface is provided with a hydrophobic coating.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: May 2, 2017
    Assignees: TECHNISCHE UNIVERSITEIT TWENTE, STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK
    Inventors: Erhan Bat, Pascal Jonkheijm, Aart Van Amerongen, Jurriaan Hüskens
  • Process for the preparation of an object supporting a lipid bilayer
    Patent number: 9550345
    Abstract: A process for the preparation of an object, supporting a lipid bilayer, for use in tissue engineering including the steps of providing an object having a surface, treating the surface of the object with a plasma containing active oxygen to provide the surface of the object with reactive groups A, to provide the surface of the object with reactive groups A, covalently attaching a sterol group to the reactive groups A and contacting the object activated with sterol groups with a lipid solution to form a lipid bilayer.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: January 24, 2017
    Assignee: UNIVERSITEIT TWENTE
    Inventors: Jasper Van Weerd, Hermanus Bernardus Johannes Karperien, Pascal Jonkheijm
  • PROCESS FOR THE PREPARATION OF AN OBJECT SUPPORTING A LIPID BILAYER
    Publication number: 20160096920
    Abstract: A process for the preparation of an object, supporting a lipid bilayer, for use in tissue engineering including the steps of providing an object having a surface, treating the surface of the object with a plasma containing active oxygen to provide the surface of the object with reactive groups A, to provide the surface of the object with reactive groups A, covalently attaching a sterol group to the reactive groups A and contacting the object activated with sterol groups with a lipid solution to form a lipid bilayer.
    Type: Application
    Filed: May 16, 2014
    Publication date: April 7, 2016
    Inventors: Jasper VAN WEERD, Hermanus Bernardus Johannes KARPERIEN, Pascal JONKHEIJM
  • STAMP FOR MAKING A MICROARRAY OF BIOMOLECULES
    Publication number: 20150306560
    Abstract: A stamp for making a microarray of biomolecules, wherein the stamp has a stamp body having a stamping surface for stamping the biomolecules onto a substrate, a plurality of reservoirs for liquids having the biomolecules, wherein each of the reservoirs has a bottom wall and a plurality of channels extending between each of the bottom wall and the stamping surface, wherein each of the reservoirs and the channels has a macroporous hydrogel and wherein the stamping surface is provided with a hydrophobic coating.
    Type: Application
    Filed: September 24, 2013
    Publication date: October 29, 2015
    Inventors: Erhan BAT, Pascal JONKHEIJM, Jurriaan HÜSKENS