Patents by Inventor Pascal Laeng

Pascal Laeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for neural stem cell differentiation using valproate
    Patent number: 7132286
    Abstract: The present invention relates to a method for differentiating a neural stem cell into a neuronal cell such as a neuroblast or neuron in vitro or in vivo. Particularly, the invention provides for a method for neural stem cell differentiation by contacting the neural stem cell with a valproate compound or analog thereof.
    Type: Grant
    Filed: June 18, 2002
    Date of Patent: November 7, 2006
    Assignee: Psychiatric Genomics, Inc.
    Inventors: Pascal Laeng, Barbara Mallon, Lee Pitts
  • Multi-parameter high throughput screening assays (MPHTS)
    Publication number: 20050181433
    Abstract: The present invention relates to screening methods and assays that are referred to herein as multi-parameter hight throughput screening (MPHTS) assays. These MPHTS assays are useful for identifying candidate pharmaceutical compounds. In particular, the screening methods of this invention may be used to identify compounds that have potential therapeutic benefits for the treatment of neuropscyhiatric and neurodegenerative disorders, including schizophrenia, bipolar affective disorder (BAD), autism and Alzheimer's disease to name a few.
    Type: Application
    Filed: April 4, 2005
    Publication date: August 18, 2005
    Applicant: Psychiatric Genomics, Inc.
    Inventors: C. Altar, Jeffrey Brockman, David Evans, Derek Hook, Leszek Klimczak, Pascal Laeng, Michael Palfreyman, Prithi Rajan
  • Gene signature of electroshock therapy and methods of use
    Publication number: 20040152107
    Abstract: Gene signatures associated with electroconvulsive therapy (ECT) and/or electroconvulsive seizures (ECS) are disclosed. Such “signatures” are useful, e.g., for diagnosing and treating neuropsychiatric disorders such as major depressive disorder (MDD), bipolar affective disorder (BAD) and psychotic depression. Such methods are therefore also provided here. The invention additionally provides screening methods that use gene signatures of the invention to identify new therapeutic compounds for treating these disorders.
    Type: Application
    Filed: September 18, 2003
    Publication date: August 5, 2004
    Inventors: C. Anthony Altar, Pascal Laeng, Theresa A. Young, Vinod D. Charles
  • Multi-parameter high throughput screening assays (MPHTS)
    Publication number: 20030096264
    Abstract: The present invention relates to screening methods and assays that are referred to herein as multi-parameter hight throughput screening (MPHTS) assays. These MPHTS assays are useful for identifying candidate pharmaceutical compounds. In particular, the screening methods of this invention may be used to identify compounds that have potential therapeutic benefits for the treatment of neuropscyhiatric and neurodegenerative disorders, including schizophrenia, bipolar affective disorder (BAD), autism and Alzheimer's disease to name a few.
    Type: Application
    Filed: June 18, 2002
    Publication date: May 22, 2003
    Applicant: Psychiatric Genomics, Inc.
    Inventors: C. Anthony Altar, Jeffrey A. Brockman, David Evans, Derek Hook, Leszek J. Klimczak, Pascal Laeng, Michael Palfreyman, Prithi Rajan
  • Method for neural stem cell differentiation using valproate
    Publication number: 20030013192
    Abstract: The present invention relates to a method for differentiating a neural stem cell into a neuronal cell such as a neuroblast or neuron in vitro or in vivo. Particularly, the invention provides for a method for neural stem cell differentiation by contacting the neural stem cell with a valproate compound or analog thereof.
    Type: Application
    Filed: June 18, 2002
    Publication date: January 16, 2003
    Applicant: Psychiatric Genomics, Inc.
    Inventors: Pascal Laeng, Barbara Mallon, Lee Pitts