Patents by Inventor Pascal Leblanc

Pascal Leblanc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW CRYSTALLINE FORMS OF A KRAS G12C INHIBITOR COMPOUND
    Publication number: 20240116900
    Abstract: Provided are crystalline forms of a KRAS G12C inhibitor compound and to processes for their preparation. Furthermore, provided is pharmaceutical composition comprising said crystalline forms, and at least one pharmaceutically acceptable excipient. The pharmaceutical composition can be used as a medicament, in particular for the treatment of cancer, and KRAS G12C-mutant cancer.
    Type: Application
    Filed: October 29, 2021
    Publication date: April 11, 2024
    Inventors: Simona COTESTA, Heng GE, Marc GERSPACHER, Catherine LEBLANC, Bo LIU, Edwige Liliane Jeanne LORTHIOIS, Rainer MACHAUER, Robert MAH, Tanja MEISTER, Christophe MURA, Pascal RIGOLLIER, Nadine SCHNEIDER, Stefan STUTZ, Andrea VAUPEL, Nicolas WARIN, Rainer WILCKEN, Lijun XUE, Marie-Anne LOZAC'H, Ross STRANG
  • PHARMACEUTICAL COMBINATIONS COMPRISING A KRAS G12C INHIBITOR AND USES OF A KRAS G12C INHIBITOR FOR THE TREATMENT OF CANCERS
    Publication number: 20240082218
    Abstract: It relates to a pharmaceutical combination comprising a KRAS G12C inhibitor, in particular 1-{6-[(4M)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro [3.3] heptan-2-yl} prop-2-en-1-one (Compound A) and one or more therapeutically active agents selected from a SHP2 inhibitor (e.g. TNO155) and a PD-1 inhibitor, pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of a cancer or a tumor, in particular wherein the cancer or tumor is KRAS G12C mutated.
    Type: Application
    Filed: December 20, 2021
    Publication date: March 14, 2024
    Inventors: Vasileios ASKOXYLAKIS, Saskia Maria BRACHMANN, Simona COTESTA, Xiaoming CUI, Jeffrey ENGELMAN, Anna FARAGO, Marc GERSPACHER, Diana GRAUS PORTA, Catherine LEBLANC, Edwige Liliane Jeanne LORTHIOIS, Bo LIU, Rainer MACHAUER, Robert MAH, Christophe MURA, Pascal RIGOLLIER, Nadine SCHNEIDER, Stefan STUTZ, Andrea Helga Emmi VAUPEL, Nicolas WARIN, Andreas WEISS, Rainer WILCKEN, Padmaja YERRAMILLI-RAO
  • Fuel supply installation of an aircraft turbojet
    Patent number: 8418964
    Abstract: A fuel supply installation for a turbojet including two volumetric pumps for combining their flow rates is disclosed. The pumps include a main pump dimensioned for the full gas rate and an auxiliary pump controlled and dimensioned to provide the supplementary flow rate necessary on ignition.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: April 16, 2013
    Assignee: Snecma
    Inventors: Pascal LeBlanc, José Roland Rodrigues
  • FUEL SUPPLY INSTALLATION OF AN AIRCRAFT TURBOJET
    Publication number: 20110243772
    Abstract: Optimisation of components of a fuel supply installation for a turbojet. The installation comprises two volumetric pumps for combining their flow rates, a main pump (14) dimensioned for the full gas rate and an auxiliary pump (16) controlled and dimensioned to provide the supplementary flow rate necessary on ignition.
    Type: Application
    Filed: December 7, 2010
    Publication date: October 6, 2011
    Applicant: SNECMA
    Inventors: Pascal LEBLANC, Jose Roland Rodrigues
  • System for injecting fuel into a turbomachine
    Patent number: 6854257
    Abstract: A system for injecting fuel into a turbomachine comprising N fuel injectors placed in a combustion chamber of the turbomachine and fed from a fuel tank, the injection system further comprising, interposed between the N injectors and the tank, a single pumping means for taking fuel from the tank and delivering N metered flow rates of fuel to the injectors.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: February 15, 2005
    Assignee: Hispano-Suiza
    Inventors: Pascal Leblanc, Pascal Marly, José Rodrigues, Alain Tiepel
  • System for injecting fuel into a turbomachine
    Publication number: 20030094197
    Abstract: A system for injecting fuel into a turbomachine comprising N fuel injectors placed in a combustion chamber of the turbomachine and fed from a fuel tank, the injection system further comprising, interposed between the N injectors and the tank, a single pumping means for taking fuel from the tank and delivering N metered flow rates of fuel to the injectors.
    Type: Application
    Filed: November 15, 2002
    Publication date: May 22, 2003
    Applicant: HISPANO-SUIZA
    Inventors: Pascal Leblanc, Pascal Marly, Jose Rodrigues, Alain Tiepel