Patents by Inventor Pascal Mertens
Pascal Mertens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11505770Abstract: The invention relates to a method for the production of hulupones, in particular for the production of hulupones products, suitable for beer bittering, essentially free of compounds, typically formed as side-products during the lupulones oxidation, that can cause negative impact in terms of aroma, taste or haze upon brewing application. The invention also relates to hulupones products, suitable for beer bittering and obtainable by the method of the invention, essentially free of compounds with negative aroma, taste or haze impact upon addition of the hulupones products during the brewing process. The invention also relates to beer bittering with hulupones products, obtainable by the method of the invention, not causing an undesirable or unacceptable aroma, taste or haze impact in the bittered beer.Type: GrantFiled: April 6, 2018Date of Patent: November 22, 2022Assignee: IFAST NV, INNOVATIVE FLAVOR & AROMA SCIENCE & TECHNOLOGYInventors: Pascal Mertens, Laurens Claes
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Patent number: 10988719Abstract: The invention relates to a method for preparing a brewed beverage, in particular a light-coloured lager or ale beer, (to be) bottled, (to be) stored, (to be) offered, (to be) served or (to be) consumed in a UV-VIS-transmittant bottle, comprising the addition of hulupones and/or reduced hulupones during the brewing process in an effective amount to obtain a brewed beverage, wherein the fraction of hulupones and/or reduced hulupones in the total of isohumulones and (reduced) hulupones is at least 25 mol %, The invention further relates to a brewed beverage, in particular a light-coloured lager beer or ale beer, bottled, (to be) stored, (to be) offered, (to be) served or (to be) consumed in a UV-VIS-transmittant bottle, comprising (reduced) hulupones and wherein the frac-tion of hulupones and/or reduced hulupones in the total of isohumulones and (reduced) hulupones is at least 25 mol %.Type: GrantFiled: September 11, 2015Date of Patent: April 27, 2021Assignee: IFAST NVInventor: Pascal Mertens
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Patent number: 10392589Abstract: The invention relates to a method for extraction into an aqueous medium of hop acids from a hop acids containing matter and for dissolution in an aqueous medium of hop acids, comprising contacting a hop acids containing matter with carbon-containing chemical substances having at least one functional group containing a nitrogen atom with a lone electron pair and at least one other polar and/or hydrophilic functional group, thereby forming complexes of hop acids with the carbon-containing chemical substances with at least one functional group containing a nitrogen atom with a lone electron pair and at least one other polar and/or hydrophilic functional group. The present invention further relates to a method for preparing a brewed beverage, particularly for brewing a beer, and in particular to a method to improve the utilization of hop acids, including alpha-acids and iso-alpha-acids, in the brewing process.Type: GrantFiled: October 21, 2014Date of Patent: August 27, 2019Assignee: IFAST NVInventor: Pascal Mertens
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Patent number: 9909088Abstract: The invention relates to a process for the production of iso-alpha-acids starting from alpha-acids in which an alpha-acid containing hop extract is mixed with a carbon-containing chemical compound with one or more functional groups containing a (basic) nitrogen atom with a lone pair (or mixtures thereof), either in solvent-free conditions or in the presence of solvents and preferably under an oxygen-free atmosphere. The resulting mixture is subjected to a temperature of at least 278 K for a time sufficient to effect the intended conversion of the alpha-acid reactant into the iso-alpha-acid product. The present invention further relates to iso-alpha-acid compositions obtained by said improved isomerisation process and to the use of said iso-alpha-acid compositions as bittering formulation and/or as source to obtain reduced or hydrogenated iso-alpha-acid compositions.Type: GrantFiled: September 29, 2011Date of Patent: March 6, 2018Assignee: IFAST NVInventors: Dirk De Vos, Pascal Mertens
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Publication number: 20150159195Abstract: A method and a device for fast amplification and detection of target nucleotide sequences possibly present in a sample, combine preferably PCR amplification with oligochromatographic detection by capillarity on a test strip.Type: ApplicationFiled: July 1, 2013Publication date: June 11, 2015Inventors: Thierry Leclipteux, Pascal Mertens, Laetitia Avrain, Isabelle Ote, Valerie Smekens
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Patent number: 8825481Abstract: Techniques are described for training a speech recognition model for accented speech. A subword parse table is employed that models mispronunciations at multiple subword levels, such as the syllable, position-specific cluster, and/or phone levels. Mispronunciation probability data is then generated at each level based on inputted training data, such as phone-level annotated transcripts of accented speech. Data from different levels of the subword parse table may then be combined to determine the accented speech model. Mispronunciation probability data at each subword level is based at least in part on context at that level. In some embodiments, phone-level annotated transcripts are generated using a semi-supervised method.Type: GrantFiled: January 20, 2012Date of Patent: September 2, 2014Assignee: Microsoft CorporationInventors: Albert Joseph Kishan Thambiratnam, Timo Pascal Mertens, Frank Torsten Bernd Seide
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Patent number: 8766013Abstract: The invention relates to a process for the production of hexahydro-iso-alpha-acids starting from iso-alpha-acids (or tetrahydro-iso-alpha-acids) in which iso-alpha-acids (or tetrahydro-iso-alpha-acids) are mixed with a heterogeneous ruthenium containing catalyst, that catalyzes the hydrogenation from iso-alpha-acids or tetrahydro-iso-alpha-acids to hexahydro-iso-alpha-acids, either in solvent-free conditions, or in the presence of a solvent phase (e.g. carbon dioxide, water, ethanol or another organic solvent, or mixtures thereof), and in the absence or presence of other hop compounds (such as beta-acids).Type: GrantFiled: June 14, 2011Date of Patent: July 1, 2014Assignee: Katholieke Universiteit LeuvenInventors: Pascal Mertens, Dirk De Vos, Bart Steenackers
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Method for isomerisation of hop alpha-acids using heterogeneous alkaline earth metal based catalysts
Patent number: 8710273Abstract: The invention relates to a process for the production of iso-alpha-acids starting from hop alpha-acids in which an hop alpha-acid containing feed is contacted with a heterogeneous alkaline earth metal based catalyst, that essentially does not dissolve in the alpha-acid containing feed or in the iso-alpha-acid product phase, either in solvent-free conditions or in the presence of water, carbon dioxide, or an organic solvent or a mixture thereof. The resulting mixture is subjected to a temperature of at least 293 K, preferably under an inert atmosphere, for a time sufficient to effect high conversion of the alpha-acid reactant into the iso-alpha-acid product. The molar ratio of alpha-acid to earth alkaline metal (Mg, Ca, Sr, Ba) varies preferably between 0.2 and 20. After the isomerization process, the heterogeneous alkaline earth metal based catalyst can be quantitatively separated from the iso-alpha-acid product phase by liquid-solid separation techniques.Type: GrantFiled: April 28, 2011Date of Patent: April 29, 2014Assignee: IFAST NVInventors: Luc De Cooman, Dirk De Vos, Pascal Mertens, Bart Steenackers -
Publication number: 20130209653Abstract: The invention relates to a process for the production of iso-alpha-acids starting from alpha-acids in which an alpha-acid containing hop extract is mixed with a carbon-containing chemical compound with one or more functional groups containing a (basic) nitrogen atom with a lone pair (or mixtures thereof), either in solvent-free conditions or in the presence of solvents and preferably under an oxygen-free atmosphere. The resulting mixture is subjected to a temperature of at least 278 K for a time sufficient to effect the intended conversion of the alpha-acid reactant into the iso-alpha-acid product. The present invention further relates to iso-alpha-acid compositions obtained by said improved isomerisation process and to the use of said iso-alpha-acid compositions as bittering formulation and/or as source to obtain reduced or hydrogenated iso-alpha-acid compositions.Type: ApplicationFiled: September 29, 2011Publication date: August 15, 2013Applicant: IFAST NVInventors: Dirk De Vos, Pascal Mertens
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Publication number: 20130191126Abstract: Techniques are described for training a speech recognition model for accented speech. A subword parse table is employed that models mispronunciations at multiple subword levels, such as the syllable, position-specific cluster, and/or phone levels. Mispronunciation probability data is then generated at each level based on inputted training data, such as phone-level annotated transcripts of accented speech. Data from different levels of the subword parse table may then be combined to determine the accented speech model. Mispronunciation probability data at each subword level is based at least in part on context at that level. In some embodiments, phone-level annotated transcripts are generated using a semi-supervised method.Type: ApplicationFiled: January 20, 2012Publication date: July 25, 2013Applicant: Microsoft CorporationInventors: Albert Joseph Kishan Thambiratnam, Timo Pascal Mertens, Frank Torsten Bernd Seide
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Publication number: 20130150626Abstract: The invention relates to a process for the production of hexahydro-iso-alpha-acids starting from iso-alpha-acids (or tetrahydro-iso-alpha-acids) in which iso-alpha-acids (or tetrahydro-iso-alpha-acids) are mixed with a heterogeneous ruthenium containing catalyst, that catalyzes the hydrogenation from iso-alpha-acids or tetrahydro-iso-alpha-acids to hexahydro-iso-alpha-acids, either in solvent-free conditions, or in the presence of a solvent phase (e.g. carbon dioxide, water, ethanol or another organ-ic solvent, or mixtures thereof), and in the absence or presence of other hop compounds (such as beta-acids).Type: ApplicationFiled: June 14, 2011Publication date: June 13, 2013Applicant: IFAST NVInventors: Pascal Mertens, Dirk De Vos, Bart Steenackers
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METHOD FOR ISOMERISATION OF HOP ALPHA-ACIDS USING HETEROGENEOUS ALKALINE EARTH METAL BASED CATALYSTS
Publication number: 20130060066Abstract: The invention relates to a process for the production of iso-alpha-acids starting from hop alpha-acids in which an hop alpha-acid containing feed is contacted with a heterogeneous alkaline earth metal based catalyst, that essentially does not dissolve in the alpha-acid containing feed or in the iso-alpha-acid product phase, either in solvent-free conditions or in the presence of water, carbon dioxide, or an organic solvent or a mixture thereof. The resulting mixture is subjected to a temperature of at least 293 K, preferably under an inert atmosphere, for a time sufficient to effect high conversion of the alpha-acid reactant into the iso-alpha-acid product. The molar ratio of alpha-acid to earth alkaline metal (Mg, Ca, Sr, Ba) varies preferably between 0.2 and 20. After the isomerisation process, the heterogeneous alkaline earth metal based catalyst can be quantitatively separated from the iso-alpha-acid product phase by liquid-solid separation techniques.Type: ApplicationFiled: April 28, 2011Publication date: March 7, 2013Applicant: IFAST NVInventors: Luc De Cooman, Dirk De Vos, Pascal Mertens, Bart Steenackers -
Patent number: 8389209Abstract: Devices for detecting analytes or analogues thereof in a biological sample are disclosed. The device includes a solid support. The solid support has several juxtaposed zones. The sample is able to migrate from a sample receiving zone towards a detection zone. The analyte, if present, is detected in the detection zone. Both zones have material allowing a capillary flow of the sample through the zones. In between the zones, there is an intermediate zone of transport of the sample which is free from any capillary material. This allows the ample to migrate by gravitational forces on the support laid in a vertical position. Methods for detecting analytes or analogues thereof in a biological sample using the device are also disclosed.Type: GrantFiled: December 8, 2006Date of Patent: March 5, 2013Assignee: Coris BioconceptInventors: Pascal Mertens, Laurence Denorme, Thierry Leclipteux
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Patent number: 7932093Abstract: The present invention relates to methods and devices for detecting one or more analytes in a biological sample, preferably a clean liquid sample. This invention in particular relates to improved rapid tests such as “dipsticks”, “lateral flow” devices and “flow-through” devices. The invention in particular relates to oligochromatographic devices that make use of a peptide- or hapten-coupled oligonucleotide and a reagent specifically recognizing the hapten or peptide and a conjugated probe that hybridizes specifically to a target sequence. It allows to detect specifically the presence of a polynucleotides directly or after molecular amplification steps with the use of a specific genuine internal control and a chromatographic control.Type: GrantFiled: April 30, 2004Date of Patent: April 26, 2011Assignee: Coris Bioconcept SPRLInventors: Ismaelle Renuart, Pascal Mertens, Thierry Leclipteux
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Publication number: 20090162833Abstract: Devices for detecting analytes or analogues thereof in a biological sample are disclosed. The device includes a solid support. The solid support has several juxtaposed zones. The sample is able to migrate from a sample receiving zone towards a detection zone. The analyte, if present, is detected in the detection zone. Both zones have material allowing a capillary flow of the sample through the zones. In between the zones, there is an intermediate zone of transport of the sample which is free from any capillary material. This allows the ample to migrate by gravitational forces on the support laid in a vertical position. Methods for detecting analytes or analogues thereof in a biological sample using the device are also disclosed.Type: ApplicationFiled: December 8, 2006Publication date: June 25, 2009Inventors: Pascal Mertens, Laurence Denorme, Thierry Leclipteux
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Publication number: 20070202497Abstract: The present invention relates to methods and devices for detecting one or more analytes in a biological sample, preferably a clean liquid sample. This invention in particular relates to improved rapid tests such as “dipsticks”, “lateral flow” devices and “flow-through” devices. The invention in particular relates to oligochromatographic devices that make use of a peptide- or hapten-coupled oligonucleotide and a reagent specifically recognizing the hapten or peptide and a conjugated probe that hybridizes specifically to a target sequence. It allows to detect specifically the presence of a polynucleotides directly or after molecular amplification steps with the use of a specific genuine internal control and a chromatographic control.Type: ApplicationFiled: April 30, 2004Publication date: August 30, 2007Applicant: Coris Bioconcept SPRL Science Park CrealysInventors: Ismaelle Renuart, Pascal Mertens, Thierry Leclipteux
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Publication number: 20060199278Abstract: The present invention relates to methods and devices for detecting one or more analytes or analyte products in a biological sample. This invention in particular relates to improved rapid tests such as “dipsticks” and “lateral flow” devices. The invention in particular relates to chromatographic device made of two active sides, in order to allow multiplex detections, quantitative or semi-quantitative detections, use of multiple sizes and kinds of particles or microspheres, use of different nitrocellulose porosities, use of different kinds of membranes. The devices described in this invention allow to detect or identify various biologicals or chemicals with one manipulation.Type: ApplicationFiled: November 2, 2005Publication date: September 7, 2006Applicant: CORIS BIOCONCEPT SPRLInventors: Thierry Leclipteux, Stephane Degallaix, Laurence Denorme, Pascal Mertens, Christine Olungu