Patents by Inventor Pascal Rigollier

Pascal Rigollier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Arylsulfonamide-based matrix metalloprotease inhibitors
    Patent number: 8222424
    Abstract: The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: July 17, 2012
    Assignee: Novartis AG
    Inventors: Claus Ehrhardt, Leslie Wighton McQuire, Pascal Rigollier, Olivier Rogel, Michael Shultz, Ruben Alberto Tommasi
  • Organic compounds and their uses
    Patent number: 8211932
    Abstract: The present application describes organic compounds of the Formula I that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: July 3, 2012
    Assignee: Novartis AG
    Inventors: Michael Patane, Prakash Raman, David Thomas Parker, Jiping Fu, Branko Radetich, Mohindra Seepersaud, Aregahegn Yifru, Rui Zheng, Trixi Brandl, Francois Lenoir, Pascal Rigollier, Oliver Simic
  • ORGANIC COMPOUNDS AND THEIR USES
    Publication number: 20110275819
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: July 19, 2011
    Publication date: November 10, 2011
    Applicant: NOVARTIS AG
    Inventors: Shawn D. BRITT, Lech Andrzej CISZEWSKI, Jiping FU, Subramanian KARUR, Yugang LIU, Peichao LU, David Thomas PARKER, Mahavir PRASHAD, Prakash RAMAN, Pascal RIGOLLIER, Mohindra SEEPERSAUD, Aregahegn YIFRU, Rui ZHENG
  • Organic compounds and their uses
    Patent number: 8008263
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: August 30, 2011
    Assignee: Novartis AG
    Inventors: Shawn D. Britt, Lech Andrzej Ciszewski, Jiping Fu, Subramanian Karur, Yugang Liu, Peichao Lu, David Thomas Parker, Mahavir Prashad, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Aregahegn Yifru, Rui Zheng
  • ORGANIC COMPOUNDS AND THEIR USES
    Publication number: 20110182850
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 7, 2010
    Publication date: July 28, 2011
    Inventors: Trixi BRANDL, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic
  • ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS
    Publication number: 20110014186
    Abstract: The present invention provides a compound of formula (I): said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP-13. Finally, the present invention also provides a pharmaceutical composition.
    Type: Application
    Filed: March 23, 2009
    Publication date: January 20, 2011
    Inventors: Claus Ehrhardt, Leslie Wighton McQuire, Pascal Rigollier, Olivier Rogel, Michael Shultz, Ruben Alberto Tommasi
  • ORGANIC COMPOUNDS AND THEIR USES
    Publication number: 20100331243
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: September 10, 2010
    Publication date: December 30, 2010
    Inventors: Trixi Brandl, Jiping Fu, Francois Lenoir, David Thomas Parker, Michael Patane, Branko Radetich, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Aregahegn Yifru, Rui Zheng
  • Organic compounds and their uses
    Patent number: 7825152
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: November 2, 2010
    Assignee: Novartis AG
    Inventors: Trixi Brandl, Jiping Fu, Francois Lenoir, David Thomas Parker, Michael Patane, Branko Radetich, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Aregahegn Yifru, Rui Zheng
  • ORGANIC COMPOUNDS AND THEIR USES
    Publication number: 20100260709
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 7, 2010
    Publication date: October 14, 2010
    Inventors: Trixi BRANDL, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic
  • Organic Compounds and their uses
    Publication number: 20100240638
    Abstract: The present application describes macrocyclic compounds of formula (I) with NS3 protease inhibitory activity for treating hepatitis C virus infection.
    Type: Application
    Filed: February 19, 2008
    Publication date: September 23, 2010
    Inventors: Shawn D. Britt, Jiping Fu, David Thomas Parker, Michiael Patane, Parkash Raman, Branko Radetich, Mohindra Seepersaud, Aregahegn Yifru, Rui Zheng, Trixi Brand, Sylvain Cottens, Claus Ehrhardt, Stefan Andreas Randl, Pascal Rigollier, Nikolaus Schiering, Oliver Simic
  • ORGANIC COMPOUNDS AND THEIR USES
    Publication number: 20100204159
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: September 11, 2007
    Publication date: August 12, 2010
    Inventors: Trixl Brandl, Sylvain Cottens, Claus Ehrhardt, Jiping Fu, Subramanian Karur, David Thomas Parker, Michael A. Patane, Prakash Raman, Stefan Andreas Randl, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic
  • Organic Compounds and Their Uses
    Publication number: 20090137495
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: October 10, 2008
    Publication date: May 28, 2009
    Inventors: Shawn D. Britt, Lech Andrzej Ciszewski, Jiping Fu, Subramanian Karur, Yugang Liu, Peichao Lu, David Thomas Parker, Mahavir Prashad, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Aregahegn Yifru, Rui Zheng
  • Organic Compounds and Their Uses
    Publication number: 20080045530
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 9, 2007
    Publication date: February 21, 2008
    Inventors: Trixi Brandl, Shawn Britt, Sylvain Cottens, Claus Ehrhardt, Jiping Fu, Subramanian Karur, Hongju Li, Peichao Lu, David Parker, Michael Patane, Branko Radetich, Prakash Raman, Stefan Randl, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Ritesh Tichkule, Yanyi Zhu
  • Organic Compounds and Their Uses
    Publication number: 20070286842
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 9, 2007
    Publication date: December 13, 2007
    Inventors: Trixi Brandl, Jiping Fu, Francois Lenoir, David Parker, Michael Patane, Branko Redetich, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Aregahegn Yifru, Rui Zheng
  • Organic Compounds and Their Uses
    Publication number: 20070265281
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: April 9, 2007
    Publication date: November 15, 2007
    Inventors: Sylvain Cottens, Claus Ehrhardt, Jiping Fu, David Parker, Michael Patane, Branko Radetich, Prakash Raman, Stefan Randl, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Dongpeng Wan
  • Azido containing tetrahydro furan compounds
    Patent number: 5705658
    Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
    Type: Grant
    Filed: February 14, 1997
    Date of Patent: January 6, 1998
    Assignee: Novartis Corporation
    Inventors: Richard Goschke, Jurgen Klaus Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim Claude Cohen, Peter Herold
  • .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acids
    Patent number: 5654445
    Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
    Type: Grant
    Filed: July 2, 1996
    Date of Patent: August 5, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Richard Goschke, Jurgen Klaus Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim Claude Cohen, Peter Herold
  • .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides
    Patent number: 5646143
    Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: July 8, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Richard Goschke, Jurgen Klaus Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim Claude Cohen, Peter Herold
  • Aromatically substituted .omega.-amino-alkanoic acid amides and alkanoic acid diamides
    Patent number: 5641778
    Abstract: Compounds of formula I ##STR1## wherein R.sub.1 is a 2-R.sub.A -3-R.sub.B -phenyl radical, a 2-R.sub.A -4-R.sub.C -phenyl radical, a 2-R.sub.A -pyridin-3-yl radical, a 3-R.sub.A -pyridin-2-yl radical or a 1-R.sub.D -indol-3-yl radical, wherein one of the radicals R.sub.A and R.sub.B is an aliphatic or heterocycloaliphatic-aliphatic radical or free or aliphatically, araliphatically or heteroaraliphatically etherified hydroxy and the other is hydrogen, an aliphatic radical or free or esterified or amidated carboxy, R.sub.C is hydrogen, an aliphatic radical, free or aliphatically, araliphatically, heteroaraliphatically or heteroarylaliphatically etherified hydroxy or an unsubstituted or heteroaliphatically substituted amino group, and R.sub.D is an aliphatic, araliphatic or heteroaliphatic radical, one of the radicals X.sub.1 and X.sub.2 is carbonyl and the other is methylene, R.sub.2 is an aliphatic radical, R.sub.3 is unsubstituted or aliphatically substituted amino, R.sub.
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: June 24, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Jurgen Klaus Maibaum, Pascal Rigollier, Peter Herold, Nissim Claude Cohen, Richard Goschke, Stefan Stutz
  • .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides
    Patent number: 5627182
    Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
    Type: Grant
    Filed: July 25, 1996
    Date of Patent: May 6, 1997
    Assignee: Ciba Geigy Corporation
    Inventors: Richard G oschke, J urgen K. Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim C. Cohen, Peter Herold