Patents by Inventor Pascale Cossart

Pascale Cossart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lactobacillus paracasei subsp. paracasei, as an agent for inhibiting listeria monocytogenes in vivo infection
    Publication number: 20140294791
    Abstract: The present invention relates to the use of the probiotic strain of Lactobacillus paracasei subsp. paracasei deposited at the CNCM under the reference I-3689, for inhibiting in vivo infection by Listeria monocytogenes.
    Type: Application
    Filed: December 1, 2011
    Publication date: October 2, 2014
    Applicants: INSTITUT PASTEUR, COMPAGNIE GERVAIS DANONE
    Inventors: Tamara Smokvina, Gianfranco Grompone, Sophie Legrain-Raspaud, Cristel Archambaud, Marc Lecuit, Pascale Cossart
  • Compositions for the treatment of tumor pathologies, comprising internalin B (ln1B) of Listeria monocytogene protein or a fragment thereof
    Publication number: 20060217308
    Abstract: The pathway by which Met is degraded after interacting with In1B, in response to Listeria monocytogenes infection, provides In1B or In1B fragments or peptides, preferably those that interfere with the interaction between In1B and Met, as new cancer treatments that can achieve rapid down-regulation and subsequent degradation of Met. In addition, this pathway highlights methods of screening for other compounds that modulate the interaction between Met and In1B and may also be used therapeutically.
    Type: Application
    Filed: March 10, 2006
    Publication date: September 28, 2006
    Inventors: Pascale Cossart, Esteban Veiga
  • Listeria monocytogenes genome, polypeptides and uses
    Publication number: 20060078901
    Abstract: The genome sequence and nucleotide sequences of Listeria monocytogenes EGD-e are provided. Polypeptide sequences, including surface or cell envelope polypeptides, and polypeptides involved in metabolism, including B12 biosynthesis, are also provided. Uses of these sequences are also provided.
    Type: Application
    Filed: January 28, 2005
    Publication date: April 13, 2006
    Inventors: Carmen Buchrieser, Lionel Frangeul, Elisabeth Couve, Christophe Rusniok, Hafida Fsihi, Pierre Dehoux, Olivier Dussurget, Farid Chetouani, Hafed Nedjari, Philippe Glaser, Franck Kunst, Pascale Cossart, Justin Daniels, Werner Goebei, Jurgen Kreft, Michael Kuhn, Eva Ng, Jose Vazquez-Boland, Gustavo Dominguez-Bernal, Patricia Garrido-Garcia, Alberto Tierrez-Martinez, Alexandra Amend, Trinad Chakraborty, Eugen Domann, Thorsten Hain, Patrick Berche, Alain Charbit, Lionel Durant, Jose-Claudio Perez-Diaz, Fernando Baquero, Francisco Garcia Del Portillo, Nuria Gomez-Lopez, Encarna Maduenio, Betriz de Pablos, Jurgen Wehland, Uwe Karst, Karl-Dieter Entian, Jorg Hauf, Matthias Rose, Hamut Voss
  • DNA probes specific for hemolytic listeria
    Patent number: 5523205
    Abstract: DNA probes are capable of hybridizing to a portion of the genome of pathogenic Listeria monocytogenes, but do not hybridize to genomes of other Listeria species and other hemolytic bacteria. These probes are useful to identify food sources infected with Listeria monocytogenes and to distinguish these food sources from those infected with non-pathogenic Listeria species. In addition, methods for the detection of pathogenic Listeria in samples using the disclosed probes are provided. A method of detection using PCR amplification with primers specific for L. monocytogenes DNA is also disclosed.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: June 4, 1996
    Assignee: Institut Pasteur
    Inventors: Pascale Cossart, Jerome Mengaud, Marlene Bohnert
  • Method for detecting Listeria monocytogenes
    Patent number: 5389513
    Abstract: A DNA probe is disclosed which is capable of hybridizing to a portion of the genome of pathogenic Listeria monocytogenes but which does not hybridize to portions of the genomes of other Listeria species and other humilytic bacteria. This probe is useful to identify food sources infected with Listeria monocytogenes and to distinguish these food services from those infected nearly with non-pathogenic Listeria species. In addition, methods for the detection of pathogenic Listeria in samples using the disclosed probes are provided.
    Type: Grant
    Filed: April 22, 1991
    Date of Patent: February 14, 1995
    Assignee: Institut Pasteur
    Inventors: Fernando Baquero, Pascale Cossart