Patents by Inventor Pascale Gaillard

Pascale Gaillard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220031570
    Abstract: The present relates to a component mixing device comprising a central unit (10) and a disposable cartridge, said central unit (10) comprising a control unit, a plurality of vial positioning elements (13) and a cavity 14 for receiving said disposable cartridge, and said disposable cartridge (20) comprising a tubing circuitry adapted to put the components housed in said plurality of vials into communication for mixing, characterized in that the mixing device is adapted to put each vial into communication with each other through said tubing circuitry of said disposable cartridge (20) and mixing said components through an compressed air mechanism (12) located in said central unit (10) and controlled by said control unit.
    Type: Application
    Filed: November 23, 2018
    Publication date: February 3, 2022
    Inventors: Julien Marine, Michel Houdou, Pascale Gaillard, Sandrine Perrotto, Philippe Bordeau
  • Patent number: 11098041
    Abstract: Imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof are useful as BTK inhibitors.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: August 24, 2021
    Assignee: Merck Patent GmbH
    Inventors: Pascale Gaillard, Jeyaprakashnarayanan Seenisamy, Lesley Liu-Bujalski, Richard D. Caldwell, Justin Potnick, Hui Qiu, Constantin Neagu, Reinaldo Jones, Annie Cho Won, Andreas Goutopoulos, Brian A. Sherer, Theresa L. Johnson, Anna Gardberg
  • Publication number: 20190233417
    Abstract: Imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof are useful as BTK inhibitors.
    Type: Application
    Filed: April 8, 2019
    Publication date: August 1, 2019
    Inventors: Pascale Gaillard, Jeyaprakashnarayanan Seenisamy, Lesley Liu-Bujalski, Richard D. Caldwell, Justin Potnick, Hui Qiu, Constantin Neagu, Reinaldo Jones, Annie Cho Won, Andreas Goutopoulos, Brian A. Sherer, Theresa L. Johnson, Anna Gardberg
  • Patent number: 10253023
    Abstract: The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: April 9, 2019
    Assignee: Merck Patent GmbH
    Inventors: Pascale Gaillard, Jeyaprakashnarayanan Seenisamy, Lesley Liu-Bujalski, Richard D. Caldwell, Justin Potnick, Hui Qiu, Constantin Neagu, Reinaldo Jones, Annie Cho Won, Andreas Goutopoulos, Brian A. Sherer, Theresa L. Johnson, Anna Gardberg
  • Publication number: 20160096834
    Abstract: The present invention relates to imidazo pyridine compounds, and pharmaceutically acceptable compositions thereof, useful as BTK inhibitors.
    Type: Application
    Filed: October 6, 2015
    Publication date: April 7, 2016
    Inventors: Pascale GAILLARD, Jeyaprakashnarayanan SEENISAMY, Lesley LIU-BUJALSKI, Richard D. CALDWELL, Justin POTNICK, Hui QIU, Constantin NEAGU, Reinaldo JONES, Annie Cho WON, Andreas GOUTOPOULOS, Brian A. SHERER, Theresa L. JOHNSON, Anna GARDBERG
  • Publication number: 20150224177
    Abstract: The present invention generally relates to a method for therapeutic or prophylactic treatment of melioidosis and/or associated diseases in a subject in need thereof, comprising administering to said subject an effective amount of a pharmaceutical composition comprising either one ion selected from the group of the hypothiocyanites (OSCN?) and/or hypohalites and/or lactoferrin or a combination thereof. The present invention also generally relates to methods of treating or preventing various bacterial infections selected from the group consisting of Burkholderia pseudomallei, Burkholderia mallei, bacillus anthracis, Yersinia pestis, and francisella tularensis infections.
    Type: Application
    Filed: February 9, 2015
    Publication date: August 13, 2015
    Inventors: Philippe BORDEAU, Pascale GAILLARD
  • Patent number: 9073940
    Abstract: This invention relates to compounds of Formula (I*) as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other diseases like cancers.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: July 7, 2015
    Assignee: MERCK SERONO SA
    Inventors: Pascale Gaillard, Isabelle Jeanclaude-Etter, Vincent Pomel, Eric Sebille, Seenisamy Jeyaprakashnarayanan, Mathilde Muzerelle
  • Patent number: 9023851
    Abstract: Compounds of the formula I in which R1 and R2 have the meanings indicated in claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: May 5, 2015
    Assignee: Merck Patent GmbH
    Inventors: Lars Burgdorf, Melanie Schultz, Carl Deutsch, Horacio Comas, Dominique Swinnen, Vincent Pomel, Pascale Gaillard, Brian Hodous
  • Patent number: 8877757
    Abstract: The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: November 4, 2014
    Assignee: Merck Serono SA
    Inventors: Pascale Gaillard, Anna Quattropani, Vincent Pomel, Thomas Rueckle, Jasna Klicic, Dennis Church
  • Publication number: 20140107116
    Abstract: The present invention is related to the use of benzothiazole derivatives for the manufacture of a medicament for the treatment of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type II, inadequate glucose tolerance, insulin resistance, obesity, polycystic ovary syndrome (PCOS). G is an unsubstituted or substituted pyrimidinyl group. L is an unsubstituted or substituted C1-C6-alkoxy, or an amino group, or an unsubstituted or a substituted 3-8 membered heterocycloalkyl, containing at least one heteroatom selected from N, O, S (e.g. a piperazine, a piperidine, a morpholine, a pyrrolidine). R1 is selected from the group comprising or consisting of hydrogen, sulfonyl, amino, unsubstituted or substituted C1-C6-alkyl, unsubstituted or substituted C2-C6-alkenyl, unsubstituted or substituted C2-C6-alkynyl or C1-C6-alkoxy, unsubstituted or substituted aryl, halogen, cyano or hydroxy.
    Type: Application
    Filed: October 8, 2013
    Publication date: April 17, 2014
    Applicant: MERCK SERONO SA
    Inventors: Pascale GAILLARD, Jean-Pierre GOTTELAND
  • Patent number: 8614215
    Abstract: The present invention is related to quinoxaline compounds of Formula (I) in particular for the treatment of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
    Type: Grant
    Filed: February 21, 2008
    Date of Patent: December 24, 2013
    Assignee: Merck Serono SA
    Inventors: Pascale Gaillard, Vincent Pomel, Isabelle Jeanclaude-Etter, Jerome Dorbais, Jasna Klicic, Cyril Montagne
  • Patent number: 8609666
    Abstract: This invention relates to compounds of Formula (I) as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other diseases like cancers.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: December 17, 2013
    Assignee: Merck Serono SA
    Inventors: Cyril Montagne, Agnés Bombrun, Gwenaelle Desforges-Bouscary, Anna Quattropani, Pascale Gaillard
  • Publication number: 20130225568
    Abstract: Compounds of the formula I in which R1 and R2 have the meanings indicated in claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis.
    Type: Application
    Filed: July 29, 2011
    Publication date: August 29, 2013
    Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG
    Inventors: Lars Burgdorf, Melanie Schultz, Carl Deutsch, Horacio Comas, Dominique Swinnen, Vincent Pomel, Pascale Gaillard, Brian Hodous
  • Publication number: 20120238545
    Abstract: This invention relates to compounds of Formula (I*) as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other diseases like cancers.
    Type: Application
    Filed: November 12, 2010
    Publication date: September 20, 2012
    Applicant: MERCK SERONO SA
    Inventors: Pascale Gaillard, Isabelle Jeanclaude-Etter, Vincent Pomel, Eric Sebille, Seenisamy Jeyaprakashnarayanan, Mathilde Muzerelle
  • Publication number: 20110319410
    Abstract: The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 29, 2011
    Applicant: MERCK SERONO SA
    Inventors: PASCALE GAILLARD, Anna Quattropani, Vincent Pomel, Thomas Rueckle, Jasna Klicic, Dennis Church
  • Publication number: 20110312960
    Abstract: The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 22, 2011
    Applicant: MERCK SERONO SA
    Inventors: Pascale Gaillard, Anna Quattropani, Vincent Pomel, Thomas Rueckle, Jasna Klicic, Dennis Church
  • Patent number: 8071597
    Abstract: The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: December 6, 2011
    Assignee: Merck Serono SA
    Inventors: Pascale Gaillard, Anna Quattropani, Vincent Pomel, Thomas Rueckle, Jasna Klicic, Dennis Church
  • Publication number: 20110293564
    Abstract: This invention relates to compounds of Formula (I) as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other deseases like cancers.
    Type: Application
    Filed: February 4, 2010
    Publication date: December 1, 2011
    Applicant: MERCK SERONO S.A.
    Inventors: Cyril Montagne, Agnés Bombrun, Gwenaelle Desforges, Anna Quattropani, Pascale Gaillard
  • Publication number: 20110257170
    Abstract: This invention relates to compounds of Formula (I) as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other diseases like cancers.
    Type: Application
    Filed: September 30, 2009
    Publication date: October 20, 2011
    Applicant: MERCK SERONO SA
    Inventors: Vincent Pomel, Pascale Gaillard, Gwenaelle Desforges, Anna Quattropani, Cyril Montagne
  • Patent number: 7855212
    Abstract: The present invention is related to pyridinyl acetonitriles as well as to pharmaceutical formulations containing such pyridinyl acetonitriles. Said pyridinyl acetonitriles are modulators of the protein kinase signalling pathways, particularly the one involving Glycogen Kinase Synthase 3 or JNK. The present invention is furthermore related to methods of preparing pyridinyl acetonitriles. X is a substituted or unsubstituted pyridinyl. G is an unsubstituted or substituted pyrimidinyl or triazinyl.
    Type: Grant
    Filed: May 3, 2004
    Date of Patent: December 21, 2010
    Assignee: Merck Serono SA
    Inventors: Matthias Schwarz, Pascale Gaillard, Jean-Pierre Gotteland, Russell J. Thomas, Patrick Page