Patents by Inventor Pascale Grel

Pascale Grel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIANTS AND EXONS OF THE GLYT1 TRANSPORTER
    Publication number: 20080201789
    Abstract: The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies.
    Type: Application
    Filed: March 18, 2008
    Publication date: August 21, 2008
    Applicant: SERONO GENETICS INSTITUTE S.A.
    Inventors: Gilbert Thill, Philippe Jais, Pascale Grel, Sandrine Mace
  • Variants and exons of the GlyT1 transporter
    Patent number: 7358066
    Abstract: The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: April 15, 2008
    Assignee: Serono Genetics Institute S.A.
    Inventors: Gilbert Thill, Philippe Jais, Pascale Grel, Sandrine Mace
  • Use of pp2a phosphatase modulators in the treatment of mental disorders
    Publication number: 20060275758
    Abstract: The invention relates to the use of PP2A/B? and to the use of a PP2A phosphatase comprising the PP2A/B? subunit for screening for modulators thereof. The use of these modulators for treating mental disorders such as bipolar disorder, schizophrenia and depression, and drugs comprising these modulators are further disclosed. The invention also discloses biallelic markers located in the gene encoding PP2A/B? and their use for diagnosing mental disorders.
    Type: Application
    Filed: June 20, 2003
    Publication date: December 7, 2006
    Applicant: Serono Genetics Institute S.A.
    Inventors: Daniel Cohen, Iiya Chumakov, Marta Blumenfeld, Sanober Shaikh, Marta Palicio-Barron, Hadi Abderrahim, Pascale Grel
  • Novel variants and exons of the glyt1 transporter
    Publication number: 20050089855
    Abstract: The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies.
    Type: Application
    Filed: July 22, 2002
    Publication date: April 28, 2005
    Inventors: Gilbert ThilI, Philippe Jais, Pascale Grel, Sandrine Mace
  • Use of PP2A phosphatase modulators in the treatment of mental disorders
    Publication number: 20040203128
    Abstract: The invention relates to the use of PP2A/B&ggr; and to the use of a PP2A phosphatase comprising the PP2A/B&ggr; subunit for screening for modulators thereof. The use of these modulators for treating mental disorders such as bipolar disorder, schizophrenia and depression, and drugs comprising these modulators are further disclosed. The present invention further provides novel PP2A/B&ggr; subunits generated by alternative splicing events. The invention also discloses biallelic markers located in the gene encoding PP2A/B&ggr; and their use for diagnosing mental disorders.
    Type: Application
    Filed: December 23, 2003
    Publication date: October 14, 2004
    Applicant: Genset S.A.
    Inventors: Daniel Cohen, Ilya Chumakov, Marta Blumenfeld, Sanober Shaikh, Marta Palicio-Barron, Hadi Abderrahim, Pascale Grel, Laurent Cavarec