Patent number: 6602897
Abstract: A compound of formula I or of formula II
wherein:
R1 is F, Cl, Br, CH2F, CF2H, or CF3;
R2 is NR6R7, where R6 is Me, Et, Pr, or iPr, and R7 is Me, Et or Pr; and
R3, R4, and R5 independently of one another each are H, Me, F, Cl, Br, CH2F, CF2H, or CF3,
and if R4 is Me, F, Cl, Br, CH2F, CF2H, or CF3, then R1 is additionally H or Me,
or a pharmacologically acceptable salt thereof. In addition, pharmaceutical compositions comprising an effective amount of these compounds, methods for the treatment or prophylaxis of urinary incontinence and diseases of the bladder using these compounds, and methods for making these compounds are disclosed.
Type:
Grant
Filed:
October 12, 2001
Date of Patent:
August 5, 2003
Assignee:
Boehringer Ingelheim Pharma KG
Inventors:
Franz Esser, Pascale Pouzet, Hisato Kitagawa, Kenji Sakai, Ikunobu Muramatsu
