Patents by Inventor Pascale RIALLAND

Pascale RIALLAND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED ANTIBODY CONSTANT REGION
    Publication number: 20200181258
    Abstract: The present invention relates to a canine IgG Fc domain, the amino acid sequence of which comprising at least one mutation selected among:—the substitution of amino acid 15.1 of CH2 domain according to the IMGT numbering system for C-domain with tyrosine;—the substitution of amino acid 16 of CH2 domain according to the IMGT numbering system for C-domain with threonine; and—the substitution of amino acid 18 of CH2 domain according to the IMGT numbering system for C-domain with glutamic acid. The present invention also relates to an Fc-fusion protein, comprising the canine IgG Fc domain, that is genetically linked to a peptide or a protein or an engineered ligand-binding proteins or a VHH domain, and to an antibody comprising the canine IgG Fc domain.
    Type: Application
    Filed: October 16, 2017
    Publication date: June 11, 2020
    Inventors: Olivier LEGER, Pascale RIALLAND, Richard MORSE