Patents by Inventor Pascual Ferrara
Pascual Ferrara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8318910Abstract: This invention relates to monoclonal and polyclonal antibodies capable of specifically recognizing IL-13 receptor ? and uses thereof.Type: GrantFiled: February 15, 2011Date of Patent: November 27, 2012Assignee: SanofiInventors: Daniel Caput, Pascual Ferrara, Patrick Laurent, Natalio Vita
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Publication number: 20110201029Abstract: This invention relates to monoclonal and polyclonal antibodies capable of specifically recognizing IL-13 receptor ? and uses thereof.Type: ApplicationFiled: February 15, 2011Publication date: August 18, 2011Applicant: SANOFI-AVENTISInventors: Daniel CAPUT, Pascual FERRARA, Patrick LAURENT, Natalio VITA
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Patent number: 7928073Abstract: This invention relates to a purified polypeptide comprising an amino acid sequence chosen from the sequence SEQ ID NO:4 or biologically active amino acid sequences derived from SEQ ID NO:4.Type: GrantFiled: July 15, 2005Date of Patent: April 19, 2011Assignee: Sanofi-AventisInventors: Daniel Caput, Pascual Ferrara, Patrick Laurent, Natalio Vita
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Publication number: 20110020951Abstract: The invention relates to new nucleic acid sequences of the family of tumor-suppressing genes related to the gene for the p53 protein, and to corresponding protein sequences.Type: ApplicationFiled: September 20, 2010Publication date: January 27, 2011Applicant: SANOFI-AVENTISInventors: Daniel CAPUT, Pascual FERRARA, Ahmed Mourad KAGHAD
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Patent number: 7838648Abstract: The invention relates to new nucleic acid sequences of the family of tumor-suppressing genes related to the gene for the p53 protein, and to corresponding protein sequences.Type: GrantFiled: May 12, 2009Date of Patent: November 23, 2010Assignee: Sanofi AventisInventors: Daniel Caput, Pascual Ferrara, Ahmed Mourad Kaghad
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Publication number: 20090258409Abstract: The invention relates to new nucleic acid sequences of the family of tumor-suppressing genes related to the gene for the p53 protein, and to corresponding protein sequences.Type: ApplicationFiled: May 12, 2009Publication date: October 15, 2009Applicant: SANOFI-AVENTISInventors: Daniel CAPUT, Pascual FERRARA, Ahmed Mourad KAGHAD
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Patent number: 7557187Abstract: The invention relates to new nucleic acid sequences of the family of tumour-suppressing genes related to the gene for the p53 protein, and to the corresponding protein sequences.Type: GrantFiled: May 5, 2005Date of Patent: July 7, 2009Assignee: sanofi-aventisInventors: Daniel Caput, Pascual Ferrara, Ahmed Mourad Kaghad
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Publication number: 20060035855Abstract: This invention relates to a purified polypeptide comprising an amino acid sequence chosen from the sequence SEQ ID NO:4 or biologically active amino acid sequences derived from SEQ ID NO:4.Type: ApplicationFiled: July 15, 2005Publication date: February 16, 2006Applicant: sanofi-aventisInventors: Daniel Caput, Pascual Ferrara, Patrick Laurent, Natalio Vita
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Publication number: 20060035856Abstract: This invention relates to monoclonal and polyclonal antibodies capable of specifically recognizing IL-13 receptor ? and/or IL13 receptor ? and uses thereof.Type: ApplicationFiled: July 15, 2005Publication date: February 16, 2006Applicant: sanofi-aventisInventors: Daniel Caput, Pascual Ferrara, Patrick Laurent, Natalio Vita
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Publication number: 20050282216Abstract: This invention relates to a purified polypeptide, comprising an amino acid sequence chosen from: a) the sequence SEQ ID No. 2, b) any biologically active sequence derived from SEQ ID No. 2.Type: ApplicationFiled: July 18, 2005Publication date: December 22, 2005Applicant: sanofi-aventisInventors: Daniel Caput, Pascual Ferrara, Patrick Laurent, Natalio Vita
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Publication number: 20050202016Abstract: The invention relates to new nucleic acid sequences of the family of tumour-suppressing genes related to the gene for the p53 protein, and to the corresponding protein sequences.Type: ApplicationFiled: May 5, 2005Publication date: September 15, 2005Applicant: sanofi-aventisInventors: Daniel Caput, Pascual Ferrara, Ahmed Kaghad
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Patent number: 6274333Abstract: This invention relates to a purified polypeptide which constitutes the type-2 neurotensin receptor (NT-R2), as well as the nucleotide sequence encoding this polypeptide.Type: GrantFiled: December 28, 1999Date of Patent: August 14, 2001Assignee: Sanofi-SynthelaboInventors: Daniel Caput, Pascale Chalon, Pascual Ferrara, Natalio Vita
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Patent number: 6235791Abstract: The present invention relates to the use of compounds capable of displacing tritiated cis-N-cyclohexyl-N-ethyl [3-(3-chloro-4-cyclohexylphenyl)-allyl]amine from its receptors for the preparation of pharmaceutical compositions intended to combat cell proliferation.Type: GrantFiled: April 12, 1999Date of Patent: May 22, 2001Assignee: Sanofi-SynthelaboInventors: Jean Claude Breliere, Pascual Ferrara, Christine Lebouteiller, Raymond Paul, Jorge Rosenfeld, Didier Van Broeck
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Patent number: 6022856Abstract: This invention relates to a purified polypeptide which constitutes the type-2 neurotensin receptor (NT-R2), as well as the nucleotide sequence encoding this polypeptide.Type: GrantFiled: May 19, 1997Date of Patent: February 8, 2000Assignee: SanofiInventors: Daniel Caput, Pascale Chalon, Pascual Ferrara, Natalio Vita
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Chemokine NC28 (monocyte chemotactic protein-3, MCP-3) polypeptides and their recombinant production
Patent number: 6001649Abstract: A new chemotactic cytokine, NC28 or Monocyte Chemotactic Protein-3 (MCP-3), is provided. Fragments of the cytokine comprising its 13 C-terminal amino acids also exhibit chemotactic activity. The polypeptides may be used as anticancer agents or immunomodulators. DNA encoding the NC28/MCP-3 polypeptides, as well as corresponding vectors and recombinant expression systems, are also provided.Type: GrantFiled: September 29, 1992Date of Patent: December 14, 1999Assignee: Societe Anonyme: Elf SanofiInventors: Daniel Caput, Pascual Ferrara, Brigitte Miloux, Adrian Minty, Natalio Vita -
Patent number: 5652123Abstract: The subject of the present invention is a protein having cytokine type activity, or a precursor of this protein, which comprises the following amino acid sequence (a1): ##STR1## in which Xaa represents Asp or Gly.Type: GrantFiled: January 11, 1995Date of Patent: July 29, 1997Assignee: Elf SanofiInventors: Daniel Caput, Pascual Ferrara, Jean-Claude Guillemot, Mourad Kaghad, Christine Labit-Le Bouteiller, Pascal Leplatois, Marilyn Magazin, Adrian Minty
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Patent number: 5541098Abstract: The invention concerns a new urate oxidase activity protein which has the following sequence (SEQ ID NO:1): ##STR1## optionally preceded by a methionine, or in that it may present a degree of substantial homology with this sequence.The invention is also aimed at medicines containing this protein as well as the genetic engineering implements to obtain it.Type: GrantFiled: September 28, 1994Date of Patent: July 30, 1996Assignee: SanofiInventors: Daniel Caput, Pascual Ferrara, Jean-Claude Guillemot, Mourad Kaghad, Richard LeGoux, G erard Loison, Elisabeth Larbre, Johannes Lupker, Pascal Leplatois, Marc Salome, Patrick Laurent
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Patent number: 5417970Abstract: An interleukin-2 preparation suitable for pharmaceutical purposes, consisting essentially of disialilated glycosylated interleukin-2, monosialilated glycosylated interleukin-2, or a mixture thereof, and substantially free of organic solvents, is isolated from recombinant CHO cells transformed with a vector containing a DNA sequence coding for a natural precursor of human interleukin-2, and is purified by a multi-step process.Type: GrantFiled: November 16, 1993Date of Patent: May 23, 1995Assignee: SanofiInventors: Willem Roskam, deceased, Bertrand Basuyaux, Pascual Ferrara, Martine Laporte, Thierry Maureaud, Natalio Vita, Alain Bayol, Genevieve Perry
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Patent number: 5382518Abstract: The invention concerns a new urate oxidase activity protein which has the following sequence:______________________________________ Ser Ala Val Lys Ala Ala Arg Tyr Gly Lys Asp Asn Val Arg Val Tyr Lys Val His Lys Asp Glu Lys Thr Gly Val Gln Thr Val Tyr Glu Met Thr Val Cys Val Leu Leu Glu Gly Glu Ile Glu Thr Ser Tyr Thr Lys Ala Asp Asn Ser Val Ile Val Ala Thr Asp Ser Ile Lys Asn Thr Ile Tyr Ile Thr Ala Lys Gln Asn Pro Val Thr Pro Pro Glu Leu Phe Gly Ser Ile Leu Gly Thr His Phe Ile Glu Lys Tyr Asn His Ile His Ala Ala His Val Asn Ile Val Cys His Arg Trp Thr Arg Met Asp Ile Asp Gly Lys Pro His Pro His Ser Phe Ile Arg Asp Ser Glu Glu Lys Arg Asn Val Gln Val Asp Val Val Glu Gly Lys Gly Ile Asp Ile Lys Ser Ser Leu Ser Gly Leu Thr Val Leu Lys Ser Thr Asn Ser Gln Phe Trp Gly Phe Leu Arg Asp Glu Tyr Thr Thr Leu Lys Glu Thr Trp Asp Arg Ile Leu Ser Thr Asp Val Asp Ala Thr Trp Gln Trp Lys Asn Phe Ser Gly Leu Gln Glu Val Arg Ser His Val Pro Lys Phe Asp Ala Thr Trp Ala Thr Ala Arg Glu Val Thr Leu Lys Thr Phe Ala Glu Asp AsnType: GrantFiled: July 28, 1992Date of Patent: January 17, 1995Assignee: SanofiInventors: Daniel Caput, Pascual Ferrara, Jean-Claude Guillemot, Mourad Kaghad, Richard Legoux, Gerard Loison, Elisabeth Larbre, Johannes Lupker, Pascal Leplatois, Marc Salome, Patrick Laurent