Patents by Inventor Pasquale Casale

Pasquale Casale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Focused Ultrasound Apparatus and Methods of Use
    Publication number: 20200078608
    Abstract: Methods for diagnosing a pathologic tissue membrane, as well as a focused ultrasound apparatus and methods of treatment are disclosed to perform ureterocele puncture noninvasively using focused ultrasound-generated cavitation or boiling bubbles to controllably erode a hole through the tissue. An example ultrasound apparatus may include (a) a therapy transducer having a treatment surface, wherein the therapy transducer comprises a plurality of electrically isolated sections, (b) at least one concave acoustic lens defining a therapy aperture in the treatment surface of the therapy transducer, (c) an imaging aperture defined by either the treatment surface of the therapy transducer or by the at least one concave acoustic lens and (d) an ultrasound imaging probe axially aligned with a central axis of the therapy aperture.
    Type: Application
    Filed: June 20, 2019
    Publication date: March 12, 2020
    Applicants: University of Washington through its Center for Commercialization, The Trustees of Columbia University in the City of New York
    Inventors: Adam Maxwell, Ryan Hsi, Thomas Lendvay, Pasquale Casale, Michael Bailey
  • Focused ultrasound apparatus and methods of use
    Patent number: 10350439
    Abstract: Methods for diagnosing a pathologic tissue membrane, as well as a focused ultrasound apparatus and methods of treatment are disclosed to perform ureterocele puncture noninvasively using focused ultrasound-generated cavitation or boiling bubbles to controllably erode a hole through the tissue. An example ultrasound apparatus may include (a) a therapy transducer having a treatment surface, wherein the therapy transducer comprises a plurality of electrically isolated sections, (b) at least one concave acoustic lens defining a therapy aperture in the treatment surface of the therapy transducer, (c) an imaging aperture defined by either the treatment surface of the therapy transducer or by the at least one concave acoustic lens and (d) an ultrasound imaging probe axially aligned with a central axis of the therapy aperture.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: July 16, 2019
    Assignees: University of Washington through its Center for Commercialization, The Trustees of Columbia University in the City of New York
    Inventors: Adam Maxwell, Ryan Hsi, Thomas Lendvay, Pasquale Casale, Michael Bailey
  • Focused Ultrasound Apparatus and Methods of Use
    Publication number: 20160287909
    Abstract: Methods for diagnosing a pathologic tissue membrane, as well as a focused ultrasound apparatus and methods of treatment are disclosed to perform ureterocele puncture noninvasively using focused ultrasound-generated cavitation or boiling bubbles to controllably erode a hole through the tissue. An example ultrasound apparatus may include (a) a therapy transducer having a treatment surface, wherein the therapy transducer comprises a plurality of electrically isolated sections, (b) at least one concave acoustic lens defining a therapy aperture in the treatment surface of the therapy transducer, (c) an imaging aperture defined by either the treatment surface of the therapy transducer or by the at least one concave acoustic lens and (d) an ultrasound imaging probe axially aligned with a central axis of the therapy aperture.
    Type: Application
    Filed: March 28, 2014
    Publication date: October 6, 2016
    Inventors: Adam Maxwell, Ryan Hsi, Thomas Lendvay, Pasquale Casale, Michael Bailey