Patents by Inventor Pasquale Degiorgio

Pasquale Degiorgio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagent composition for the analysis of residual white blood cells in leuko-reduced blood banking products
    Patent number: 7745219
    Abstract: The enumeration and analysis of residual white blood cells in a sample of leukocyte-reduced blood products is conducted by forming a suspension of the leukocyte-reduced blood products with a sufficient amount of a lysing reagent. The lysing reagent comprises a buffer with a low molar concentration, and a non-ionic surfactant. The suspension of leukocyte-reduced blood products and the lysing reagent is incubated for a sufficient time at a temperature sufficient to selectively lyse the platelets and red blood cells without damaging the white blood cells. The white blood cells of the lysed blood products are then contacted with a suitable dye to stain the white blood cells and the number of stained white blood cells is measured. The lysing reagent is free of harsh organic solvents which can damage the plastic components of automated clinical analyzers.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: June 29, 2010
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Michael J. Sommer, Pasquale Degiorgio, Bronislaw P. Czech, Gena Fischer, E. Sabrinah Chapman, David Zelmanovic, Jolanta Kunicka
  • Reagent composition for the analysis of residual white blood cells in leuko-reduced blood banking products
    Publication number: 20050026240
    Abstract: The enumeration and analysis of residual white blood cells in a sample of leukocyte-reduced blood products is conducted by forming a suspension of the leukocyte-reduced blood products with a sufficient amount of a lysing reagent. The lysing reagent comprises a buffer with a low molar concentration, and a non-ionic surfactant. The suspension of leukocyte-reduced blood products and the lysing reagent is incubated for a sufficient time at a temperature sufficient to selectively lyse the platelets and red blood cells without damaging the white blood cells. The white blood cells of the lysed blood products are then contacted with a suitable dye to stain the white blood cells and the number of stained white blood cells is measured. The lysing reagent is free of harsh organic solvents which can damage the plastic components of automated clinical analyzers.
    Type: Application
    Filed: July 21, 2004
    Publication date: February 3, 2005
    Inventors: Michael Sommer, Pasquale Degiorgio, Bronislaw Czech, Gena Fischer, E. Chapman, David Zelmanovic, Jolanta Kunicka