Patents by Inventor Pathi L. Srinivas

Pathi L. Srinivas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF IRBESARTAN HYDROCHLORIDE
    Publication number: 20090137648
    Abstract: The present invention is concerned with a process for the preparation of 2n-butyl-4-spirocyclopentane-1-[(2?-(tetrazol-5-yl)biphenyl-4-yl)methyl]-2-imidazolin-5-one hydrochloride, irbesartan hydrochloride, novel hydrated and anhydrous crystalline forms thereof, amorphous irbesartan hydrochloride, formulations containing the same, therapeutic uses thereof and methods of treatment employing the same. The process of the present invention is a one-pot process which comprises reacting intermediate compounds 2n-butyl-1,3-diazaspiro[4,4]non-1-en-4-one and 5-(4?-bromomethyl-biphenyl-2-yl)-1-trityl-1H-tetrazole.
    Type: Application
    Filed: October 26, 2005
    Publication date: May 28, 2009
    Inventors: Pathi L. Srinivas, Jayamadhava P. Relekar, Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
  • Pharmaceutical process and compounds prepared thereby
    Patent number: 7439367
    Abstract: The present invention relates to an improved process for the preparation of a sulfinyl compound of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, from a sulfide compound of formula (II), wherein in both formulae (I) and (II) R1 and R3 are selected from the group consisting of hydrogen, methyl or C1-4alkoxy, R2 is selected from the group consisting of substituted or unsubstituted C1-4alkoxy and R4 is selected from the group consisting of hydrogen or substituted or unsubstituted C1-4alkoxy.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: October 21, 2008
    Assignee: CIPLA Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Pathi L. Srinivas