Abstract: A microscope system includes: at least one microscope component with electrically adjustable component parameters; a controller for generating electrical signals and transmitting the electrical signals to the at least one microscope component to set the electrically adjustable component parameters; and a computer having at least one display unit, the computer generating an input unit having a graphical user interface on the at least one display unit, at least three setting parameters being adjustable by the graphical user interface. The input unit has an input pointer that is positionable in an input area so as to set a respective value for the at least three setting parameters. A coordinate axis is defined in the input area for each of the at least three setting parameters, with at least one coordinate axis not being perpendicular to another coordinate axis. Values of the at least three setting parameters are determined by the coordinates.

Abstract: An optical imaging device for a microscope comprises a first optical system configured to form a first optical image corresponding to a first region of a sample in accordance with a first imaging mode, a second optical system configured to form a second optical image corresponding to a second region of said sample, wherein said first and second regions spatially coincide in a target region of said sample and said first and second imaging modes are different from each other, a memory storing first distortion correction data suitable for correcting a first optical distortion caused by said first optical system in said first optical image, second distortion correction data suitable for correcting a second optical distortion caused by said second optical system in said second optical image, and transformation data suitable for correcting positional misalignment between said first and second optical images, and a processor which is configured to process first image data representing said first optical image based

Abstract: A computer-implemented method for determining a value for at least three setting parameters by means of an input unit in the form of a graphical user interface with an input cursor positionable in an input area is provided. At least two of the at least three setting parameters can be set independently of one another. The method includes determining a position of the input cursor within the input area; determining a coordinate of the position of the input cursor for each particular setting parameter of the at least three setting parameters as a function of a distance in each case of the position of the input cursor from at least one coordinate origin allocated to the particular setting parameter; and determining a value for each particular setting parameter of the at least three setting parameters as a function of the coordinate determined for each particular setting parameter.

Abstract: An image annotation system for annotating a microscopic image of a sample includes an output unit configured to display the image of the sample, and an input unit configured to capture a first and second user input sequence including a first and second movement of a cursor over the image, the first and second movement defining a first and second closed path. The image annotation system also includes a processor configured to determine a first image area, determine whether the second closed path includes at least one proximity section, when the second closed path does not include the proximity section, to determine a second image area, and when the second closed path does include the proximity section, to determine the second image area and at least one area between the border of the first image area and the at least one proximity section.

Abstract: An image annotation system for annotating a microscopic image of a sample is provided. The image annotation system includes an output unit configured to display the image of the sample, and an input unit configured to capture a first and second user input sequence including a first and second movement of a cursor over a first and second selection area of the displayed image. The image annotation system also includes a processor configured to determine at least one image area of the image of the sample by determining a first image area based on the first selection area, based on the second movement beginning within the first selection area, redetermine the first image area based on the first and second selection areas, and based on the second movement beginning outside the first selection area, determining a second image area based on the second selection area.

Abstract: A controller for providing an operational setting of an imaging device is configured to provide a user with a preferred operational setting for acquiring an image. The controller is also configured to receive a user input and generate a response information based on the user input, the response information indicating whether or not the image generated by the imaging device is accepted by the user. The controller is further configured to update the preferred operational setting using a machine learning algorithm based on the response information.

Abstract: A device for receiving samples in a microscope is provided. The device comprises a microtiter plate. The microtiter plate comprises an inner part with cavities for the samples and with an optically transparent bottom plate, which seals the cavities underneath and a frame which defines a supporting surface and is configured to hold the inner part at least in a first position. The bottom plate is arranged above the supporting surface in the first position of the inner part. The inner part is movable relative to the frame along a direction (A) perpendicular to the supporting surface.

Abstract: A method for image generation by means of a microscope includes: locating a sample to be imaged in an object space of the microscope for the image generation using specified image generation parameters; firstly detecting a movement or an intended movement of the sample; and thereupon automatically changing at least one image generation parameter during the movement of the sample depending on a movement variable.

Abstract: A microscope system includes: at least one microscope component with electrically adjustable component parameters; a controller for generating electrical signals and transmitting the electrical signals to the at least one microscope component to set the electrically adjustable component parameters; and a computer having at least one display unit, the computer generating an input unit having a graphical user interface on the at least one display unit, at least three setting parameters being adjustable by the graphical user interface. The input unit has an input pointer that is positionable in an input area so as to set a respective value for the at least three setting parameters. A coordinate axis is defined in the input area for each of the at least three setting parameters, with at least one coordinate axis not being perpendicular to another coordinate axis. Values of the at least three setting parameters are determined by the coordinates.

Abstract: An apparatus for displaying and/or printing images of a specimen, including a first and second fluorophores and a second fluorophore, comprises an image acquisition unit configured to acquire first and second raw images captured by detecting first and second fluorescence light, having different spectral compositions, emitted by the first and second fluorophores, respectively. Each of the raw images comprises pixels each having a brightness value. The image processor is configured to: select first and second hues, that are different from each other, from a predetermined sequence of hues; generate a first false color image by assigning the first hue to each pixel of the first raw image; and generate a second false color image by assigning the second hue to each pixel of the second raw image. The output unit is configured to display and/or print the first and second false color images.

Abstract: An optical imaging device for a microscope comprises a first optical system configured to form a first optical image corresponding to a first region of a sample in accordance with a first imaging mode, a second optical system configured to form a second optical image corresponding to a second region of said sample, wherein said first and second regions spatially coincide in a target region of said sample and said first and second imaging modes are different from each other, a memory storing first distortion correction data suitable for correcting a first optical distortion caused by said first optical system in said first optical image, second distortion correction data suitable for correcting a second optical distortion caused by said second optical system in said second optical image, and transformation data suitable for correcting positional misalignment between said first and second optical images, and a processor which is configured to process first image data representing said first optical image based