Patents by Inventor Patrice Renaut

Patrice Renaut has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5883132
    Abstract: The present invention relates to compounds selected from the group consisting of:(i) the compounds of the formula ##STR1## in which: R is a hydrogen atom, a group OH, a group OCH.sub.3 or a group CH.sub.2 OH,*C, in the case where R is not a hydrogen atom, is an asymmetric carbon atom of (R,S), (R) or (S) configuration, and**C is an asymmetric carbon atom of (R,S) or (R) configuration; and(ii) their addition salts.It further relates to the method of preparing these compounds, to their use in therapeutics and in the field of analysis, and to intermediates.
    Type: Grant
    Filed: October 10, 1996
    Date of Patent: March 16, 1999
    Assignee: Fournier Industrie Et Sante
    Inventors: Luc Lebreton, Patrice Renaut, Philippe Durand
  • Patent number: 5733928
    Abstract: The present invention relates to a novel compound selected from the group consisting of:(i) the compounds of the formula ##STR1## in which: A is a group --CO--NH-- or a group --NH--CO--,R is a hydrogen atom or a methyl group, and*C, if R is not the hydrogen atom, is an asymmetric carbon of (R,S) or (R) configuration; and(ii) their addition salts.It further relates to the method of preparing this compound and to its use in therapeutics.
    Type: Grant
    Filed: May 15, 1996
    Date of Patent: March 31, 1998
    Assignee: Fournier Industrie et Sante
    Inventors: Luc Lebreton, Patrice Renaut, Christine Dumas
  • Patent number: 5637613
    Abstract: The present invention relates, by way of novel industrial products, to compounds which are structurally related to 15-deoxyspergualin and which have the formula ##STR1## in which: A is a single bond, a group --CH.sub.2 --, a group --CH.sub.2 O--, a group --CH.sub.2 NH--, a group --CH(OH)--, a group --CHF-- or a group --CH(OCH.sub.3)--, andn is equal to 6 or 8,and their addition salts.These novel compounds are useful especially as immunosuppressants. The invention further relates to the method of preparing said compounds.
    Type: Grant
    Filed: February 23, 1995
    Date of Patent: June 10, 1997
    Assignee: Fournier Industrie et Sante
    Inventors: Patrice Renaut, Luc Lebreton, Patrick Dutartre, Soth Samreth, Catherine Derrepas, Jean M. Rognon
  • Patent number: 5580881
    Abstract: 1,2,3,5,6,7,8,8a-Octahydro-5,5,8a-trimethyl-(8a.beta.)-isoquinolineamines of formula (I), wherein groups R.sup.1 -R.sup.3 are as defined in the description, a method for preparing same, and therapeutical uses thereof as agents for inhibiting the biosynthesis of cholesterol, particularly epoxysqualene cyclase, which are useful as cholesterol and lipid lowering drugs, antiatheromatic and antifungal agents.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: December 3, 1996
    Assignee: Fournier Industrie Et Sante
    Inventors: Jean Binet, Soth Samreth, Daniel De Fornel, Thierry Boucher, Patrice Renaut
  • Patent number: 5476870
    Abstract: The present invention relates, by way of novel industrial products, to compounds which are structurally related to 15-deoxyspergualin. These novel compounds have the formula ##STR1## in which: n is equal to 6 or 8 andA is a single bond, CH.sub.2, CHF, CH(OH), CH(OCH.sub.3), CH.sub.2 NH or CH.sub.2 O,and their addition salts.
    Type: Grant
    Filed: December 2, 1993
    Date of Patent: December 19, 1995
    Assignee: Fournier Industrie ET Sante
    Inventors: Patrice Renaut, Luc Lebreton, Patrick Dutartre, Philippe Derrepas, Soth Samreth
  • Patent number: 5169838
    Abstract: The present invention relates, by way of novel industrial products which are useful in therapy, to the benzopyranone-.beta.-D-thioxyloside compounds of the formula ##STR1## in which: one of the substituents R or R' is an oxygen atom double-bonded to the corresponding cyclic carbon atom and the other is a group R.sub.1,the symbol represents a double bond conjugated to the CO group provided by one of the substituents R or R',X is a sulfur atom or an oxygen atom,R.sub.1 and R.sub.2, which are identical or different, are each a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group, a halogen atom, a trifluoromethyl group or a phenyl group, it being possible for R.sub.1 and R.sub.2, taken together, to form a 7,8,9,10-tetrahydrodibenzo[b,d]pyran-6-one group or a 1,2,3,4-tetrahydro-9H-xanthen-9-one group with the benzopyranone group to which they are bonded, andY is the hydrogen atom or an aliphatic acyl group.
    Type: Grant
    Filed: September 10, 1990
    Date of Patent: December 8, 1992
    Assignee: Fournier Industrie et Sante
    Inventors: Soth Samreth, Veronique Barberousse, Patrice Renaut, Francois Bellamy, Jean Millet
  • Patent number: 5100913
    Abstract: The present invention relates, by way of novel industrial products, to the sulfonylphenyl-.beta.-D-thioxyloside compounds of the formula ##STR1## in which: X is a sulfur atom or an oxygen atom;R is a C.sub.1 -C.sub.4 alkyl group, a substituted amino group NR.sub.1 R.sub.2 (where R.sub.1 and R.sub.2, which are identical or different, are each a C.sub.1 -C.sub.4 alkyl group, it being possible for R.sub.1 and R.sub.2, taken together, to form a piperidinyl or morpholinyl group with the nitrogen atom to which they are bonded) or a phenyl group which is unsubstituted or substituted in the para position by a cyano group or by a halogen atom; andY is the hydrogen atom or an aliphatic acyl group.These compounds are useful in therapeutics, especially as venous antithrombotics.
    Type: Grant
    Filed: March 25, 1991
    Date of Patent: March 31, 1992
    Assignee: Fournier Industrie et Sante
    Inventors: Soth Samreth, Patrice Renaut, Jerzy Bajgrowicz, Jean Millet
  • Patent number: 5101048
    Abstract: The present invention relates, by way of novel industrial products, to the .beta.-D-phenylthioxyloside compounds of the formula ##STR1## in which: X represents a sulfur atom or an oxygen atom;R.sub.1, R.sub.2 and R.sub.3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group --CO--R (in which R represents a C.sub.1 -C.sub.4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH.sub.3), a C.sub.1 -C.sub.4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for R.sub.1 and R.sub.2, taken together, to form, with the phenyl group to which they are bonded, a .beta.-naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; andY represents the hydrogen atom or an aliphatic acyl group.These compounds are useful as therapeutic agents, especially as venous antithrombotics.
    Type: Grant
    Filed: October 18, 1989
    Date of Patent: March 31, 1992
    Assignee: Fournier Industrie et Sante
    Inventors: Jerzy Bajgrowicz, Patrice Renaut, Veronique Barberousse, Soth Samreth, Jean Millet, Francois Bellamy
  • Patent number: 4897409
    Abstract: A mixture of the 4 stereoisomers of formula (I) below, each of the pairs of corresponding racemic diastereoisomers and each of the enantiomers corresponding to each pair, that is to say each of said stereoisomers: ##STR1## in which R.sub.1 represents: a hydrogen atom,an alkoxy group comprising from 1 to 4 carbon atoms,a trifluoromethyl group, orone or two halogen atoms;and the pair (R.sub.2, R.sub.3) has one of the following meanings: (H, H), (H, C.sub.1 -C.sub.4 alkyl), (C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkyl), as well as their organic and inorganic acid addition salts.The compounds of formula (I) are therapeutically useful.
    Type: Grant
    Filed: September 2, 1987
    Date of Patent: January 30, 1990
    Assignee: Delalande S.A.
    Inventors: Michel Langlois, Alain-Rene Schoofs, Jean-Francois Rumigny, Philippe Dostert, Margherita Strolin-Benedetti, Patrice Renaut