Patents by Inventor Patricia A. Basford

Patricia A. Basford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparation of 1-(2s,3s)-2-benzhydryl-n-(5- tert-butyl-2-methoxybenzyl)quinuclidin-3-amine
    Publication number: 20090099364
    Abstract: This invention relates to an improved process for the preparation of (2S,3S)-2-benzhydryl-N-(5-tent-butyl-2-methoxybenzyl)quinuclidin-3-amine, (hereinafter “compound of Formula I”) and its pharmaceutically acceptable salts. In particular, the invention is directed to an improved synthesis of the monohydrate citrate salt of the compound of Formula (Ia).
    Type: Application
    Filed: January 26, 2005
    Publication date: April 16, 2009
    Inventors: Patricia A. Basford, Ronald J. Post, Julina D. Smith, Geraldine P. Taber
  • Tropane derivatives useful in therapy
    Publication number: 20070185157
    Abstract: The present invention provides compounds of formula (I) wherein X, Y, R1, R2 and R3 are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
    Type: Application
    Filed: April 4, 2007
    Publication date: August 9, 2007
    Inventors: Patricia Basford, Peter Stephenson, Stefan Taylor, Anthony Wood
  • Tropane derivatives useful in therapy
    Publication number: 20050107424
    Abstract: The present invention provides compounds of formula (I) wherein X, Y, R1, R2 and R3 are as defined hereinabove. The compounds of the present invention are modulators, especially antagonists, of the activity of chemokine CCR5 receptors. Modulators of the CCR5 receptor may be useful in the treatment of various inflammatory diseases and conditions, and in the treatment of infection by HIV and genetically related retroviruses.
    Type: Application
    Filed: December 15, 2004
    Publication date: May 19, 2005
    Inventors: Patricia Basford, Peter Stephenson, Stefan Taylor, Anthony Wood