Patents by Inventor Patricia A. Kasila

Patricia A. Kasila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme assay using a solid phase substrate
    Patent number: 5972595
    Abstract: This invention relates to a hydrophobic layer formed on a solid support, the hydrophobic layer incorporating by hydrophobic interactions an amphipathic enzyme substrate labeled with a reporter on its hydrophilic region, and the use of the same to conduct various enzyme assays without extraction steps.
    Type: Grant
    Filed: December 16, 1998
    Date of Patent: October 26, 1999
    Assignee: NEN Life Science Products, Inc.
    Inventors: Patricia Kasila, Thomas R. Mullinax, Michael E. Bembenek, Mark N. Bobrow
  • Assay device and immunoassay
    Patent number: 5391478
    Abstract: This invention relates to an improved assay device and assay for detecting or quantitating the presence or absence of a substance in a sample. The device has multiple layers comprising a permeable layer (a) having a capture reagent attached to less than the entire membrane, a selectively permeable layer (b) which does not allow assay reagents to pass through (b) and an absorbent layer (c). Layer (b) is in communication with layers (a) and (c). Layer (b) has at least one hole extending therethrough and the hole or holes are directly below the capture reagent in layer (a). The area of the hole or the combined area of the holes is less than the area covered by the capture reagent. This invention also relates to a method of reducing background color development in an absorbent layer of an assay device.
    Type: Grant
    Filed: February 21, 1992
    Date of Patent: February 21, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Richard A. Greene, Patricia A. Kasila
  • Assay device and immunoassay
    Patent number: 5137804
    Abstract: This invention relates to an improved assay device and assay for detecting or quantitating the presence or absence of a substance in a sample. The device has multiple layers comprising a permeable layer (a) having a capture reagent attached to less than the entire membrane, a selectively permeable layer (b) which does not allow assay reagents to pass through (b) and an absorbent layer (c). Layer (b) is in communication with layers (a) and (c). Layer (b) has at least one hole extending therethrough and the hole or holes are directly below the capture reagent in layer (a). The area of the hole or the combined area of the holes is less than the area covered by the capture reagent. This invention also relates to a method of reducing background color development in an absorbent layer of an assay device.
    Type: Grant
    Filed: May 10, 1988
    Date of Patent: August 11, 1992
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Richard A. Greene, Patricia A. Kasila