Abstract: The present disclosure provides crystalline and amorphous forms of 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-(2-propanyl)-3-pyridinyl)-4-((2S)-2-methyl-4-(2-propenoyl)-1-piperazinyl)pyrido[2,3-d]pyrimidin-2(1H)-one, including several anhydrous, hydrate and solvate forms, and solid state forms thereof, pharmaceutical compositions, and methods of treating a disease mediated by KRAS G12C inhibition.

Abstract: A bottle contaminant remover comprising a curved shank, an extension member and a hook member. The extension member extends from one end of the curved shank at an obtuse angle. A hook member extends from the extension member at an acute angle. The distance between the extension member—hook member junction and the end of the hook member is less than the diameter of the bottle opening of the bottle containing the contaminant. The shank, the extension member and the hook member form a cup like structure for grasping the bottle contaminant. A handle is attached to the shank to permit a user to hold the device and to apply finger pressure to the shank. To use the device it is inserted into a bottle. The contaminant is grasped. The device and the contaminant are then removed from the bottle.

Abstract: The present invention generally relates to a container for an article and a process of use thereof. The article can include a body forming a pocket for receiving and displaying the article; and a coupler connected to the body. The coupler can be adapted to secure the container to a doorknob.

Abstract: This invention provides a method of preparing a silver halide photographic emulsion which comprises adding to the silver halide emulsion after precipitation and before or during sensitization a disulfide compound and a sulfinate compound, wherein the disulfide compound and the sulfinate compound are added simultaneously. It further provides a silver halide photographic emulsion prepared by the above method.