Patents by Inventor Patricia Burke

Patricia Burke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANCER STEM CELLS AND METHODS OF USING THE SAME
    Publication number: 20150168375
    Abstract: Provided are methods of culturing cancer stem cells in vitro, where the cancer stem cells have been obtained from the peripheral blood of a patient, and methods of using the cultured cancer stem cells in a xenograft model of cancer and for in vivo and in vitro screening of test compounds. Also provided is an enriched population of cancer stem cells obtained from the peripheral blood of a patient.
    Type: Application
    Filed: March 12, 2013
    Publication date: June 18, 2015
    Applicant: MEDIMMUNE, LLC
    Inventors: Haifeng Bao, Xiaoru Chen, Patricia Burke, Xiaoqing Shi, Sanjoo Jalla
  • METHODS TO MOLECULARLY CHARACTERIZE CIRCULATING TUMOR CELLS
    Publication number: 20110256155
    Abstract: The invention relates to a rapid, sensitive method to obtain a gene expression profile from a target cell population in a blood sample. The target cells can be circulating tumor cells. Disclosed are methods and kits for obtaining such profiles.
    Type: Application
    Filed: April 18, 2011
    Publication date: October 20, 2011
    Applicant: MEDIMMUNE, LLC
    Inventors: Jiaqi Huang, Haifeng Bao, Philip Brohawn, Patricia Burke, Xiaoru Chen, Theresa Lavallee, Yihong Yao
  • Method of treating tumors
    Publication number: 20060153770
    Abstract: A method of treating tumors, such as prostate tumors, breast tumors, non-Hodgkin's lymphoma, and the like, includes the sequential steps of administering to the patient at least one dose of an antiangiogenic cyclo-arginine-glycine-aspartic acid-containing pentapeptide (cRGD pentapeptide); administering to the patient an anti-tumor effective amount of a radioimmunotherapeutic agent (RIT); and then administering to the patient at least one additional dose of cRGD pentapeptide. The cRGD pentapeptide is preferably cyclo-(Arg-Gly-Asp-D-Phe-[N-Me]-Val), and the RIT is preferably a radionuclide-labeled chelating agent-ligand complex in which chelating agent is chemically bonded to a tumor-targeting molecule, such as a monoclonal antibody.
    Type: Application
    Filed: March 17, 2006
    Publication date: July 13, 2006
    Inventors: Sally DeNardo, Patricia Burke, Gerald DeNardo, Simon Goodman, Siegfried Matzku, Kerstin Matzku
  • Method of treating tumors
    Patent number: 7029652
    Abstract: A method of treating tumors, such as prostate tumors, breast tumors, non-Hodgkin's lymphoma, and the like, includes the sequential steps of administering to the patient at least one dose of an antiangiogenic cyclo-arginine-glycine-aspartic acid-containing pentapeptide (cRGD pentapeptide); administering to the patient an anti-tumor effective amount of a radioimmunotherapeutic agent (RIT); and then administering to the patient at least one additional dose of cRGD pentapeptide. The cRGD pentapeptide is preferably cyclo-(Arg-Gly-Asp-D-Phe-[N-Me]-Val), and the RIT is preferably a radionuclide-labeled chelating agent-ligand complex in which chelating agent is chemically bonded to a tumor-targeting molecule, such as a monoclonal antibody.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: April 18, 2006
    Assignees: The Regents of the University of California, Merck Patent GmbH
    Inventors: Sally J. DeNardo, Patricia A. Burke, Gerald L. DeNardo, Simon Goodman, Kerstin Matzku, legal representative, Siegfried Matzku, deceased
  • Method of treating tumors
    Publication number: 20030143157
    Abstract: A method of treating tumors, such as prostate tumors, breast tumors, non-Hodgkin's lymphoma, and the like, includes the sequential steps of administering to the patient at least one dose of an antiangiogenic cyclo-arginine-glycine-aspartic acid-containing pentapeptide (cRGD pentapeptide); administering to the patient an anti-tumor effective amount of a radioimmunotherapeutic agent (RIT); and then administering to the patient at least one additional dose of cRGD pentapeptide. The cRGD pentapeptide is preferably cyclo-(Arg-Gly-Asp-D-Phe-[N-Me]-Val), and the RIT is preferably a radionuclide-labeled chelating agent-ligand complex in which chelating agent is chemically bonded to a tumor-targeting molecule, such as a monoclonal antibody.
    Type: Application
    Filed: July 31, 2002
    Publication date: July 31, 2003
    Inventors: Sally J. DeNardo, Patricia A. Burke, Gerald L. DeNardo, Simon Goodman, Siegfried Matzku
  • Decorative mouse cover
    Patent number: D420339
    Type: Grant
    Filed: April 1, 1998
    Date of Patent: February 8, 2000
    Inventor: Patricia A. Burke