Patents by Inventor Patricia C. Brzostowicz

Patricia C. Brzostowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7105296
    Abstract: Genes have been isolated from a variety of bacteria encoding Baeyer-Villiger monooxygenase activity. The genes and their products are useful for the conversion of ketones to the corresponding esters. A series of motifs, common to all genes, has been identified as diagnostic for genes encoding proteins of this activity.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: September 12, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Michael G. Bramucci, Patricia C. Brzostowicz, Kristy N Kostichka, Vasantha Nagarajan, Pierre E. Rouviere, Stuart M. Thomas
  • Patent number: 7087403
    Abstract: Mutant phytoene desaturase genes are provided encoding polypeptides having the ability to convert a phytoene desaturase substrate to tetradehydrolycopene. Both in vivo and in vitro methods are provided using the present phytoene desaturases for tetradehydrolycopene production.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: August 8, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Patricia C. Brzostowicz, Pierre E. Rouviere, Dana M. Walters Pollak
  • Patent number: 7034140
    Abstract: Genes have been isolated from Rhodococcus erythropolis AN12 strain encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Rhodococcus strain. The genes and gene products of the present invention may be used in a variety of ways for the production of isoprenoid compounds in a variety of organisms.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: April 25, 2006
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Michael G. Bramucci, Patricia C. Brzostowicz, Qiong Cheng, Kristy N Kostichka, Pierre E. Rouviere, Vasantha Nagarajan, Luan Tao, Stuart M. Thomas
  • Patent number: 6969595
    Abstract: A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: November 29, 2005
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Deana DiCosimo, Mattheos Koffas, Edward S. Miller, James M. Odom, Stephen K. Picataggio, Pierre E. Rouviere
  • Publication number: 20040267001
    Abstract: Genes have been isolated from a variety of bacteria encoding Baeyer-Villiger monooxygenase activity. The genes and their products are useful for the conversion of ketones to the corresponding esters. A series of motifs, common to all genes, has been identified as diagnostic for genes encoding proteins of this activity.
    Type: Application
    Filed: July 7, 2004
    Publication date: December 30, 2004
    Inventors: Michael G. Bramucci, Patricia C. Brzostowicz, Kristy N. Kostichka, Vasantha Nagarajan, Pierre E. Rouviere, Stuart M. Thomas
  • Patent number: 6790645
    Abstract: Two gene clusters have been isolated from an Brevibacterium sp HCU that encode the enzymes expected to convert cyclohexanol to adipic acid. Individual open reading frames (ORF's) on each gene cluster are useful for the production of intermediates in the adipic acid biosynthetic pathway or of related molecules. All the ORF's have been sequenced. Identification of gene function has been made on the basis of sequence comparison and biochemical analysis.
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: September 14, 2004
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Patricia C. Brzostowicz, Pierre E. Rouviere
  • Publication number: 20040077068
    Abstract: A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields.
    Type: Application
    Filed: September 4, 2003
    Publication date: April 22, 2004
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Deana J. Dicosimo, Mattheos Koffas, Edward S. Miller, James Martin Odom, Stephen K. Picataggio, Pierre E. Rouviere
  • Publication number: 20030170847
    Abstract: Genes have been isolated from Rhodococcus erythropolis AN12 strain encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Rhodococcus strain. The genes and gene products of the present invention may be used in a variety of ways for the production of isoprenoid compounds in a variety of organisms.
    Type: Application
    Filed: April 22, 2002
    Publication date: September 11, 2003
    Inventors: Michael G. Bramucci, Patricia C. Brzostowicz, Qiong Cheng, Kristy N. Kostichka, Pierre E. Rouviere, Vasantha Nagarajan, Luan Tao, Stuart M. Thomas
  • Publication number: 20030148319
    Abstract: Genes have been isolated from Pantoea stewartii encoding geranylgeranyl pyrophosphate (GGPP) synthase (crtE), phytoene synthase (crtB), phytoene desaturase(crtI), lycopene cyclase(crtY), &bgr;-carotene hydroxylase(crtZ), and zeaxanthin glucosyl transferase (crtX) activity. The genes and their products are useful for the conversion of phytoene to the carotenoids. Vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes and &bgr;-carotene by recombinant DNA technology in transformed host organisms are disclosed.
    Type: Application
    Filed: August 13, 2002
    Publication date: August 7, 2003
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Stephen K. Picataggio, Pierre E. Rouviere
  • Publication number: 20030124695
    Abstract: Genes have been isolated from a variety of bacteria encoding Baeyer-Villiger monooxygenase activity. The genes and their products are useful for the conversion of ketones to the corresponding esters. A series of motifs, common to all genes, has been identified as diagnostic for genes encoding proteins of this activity.
    Type: Application
    Filed: August 28, 2002
    Publication date: July 3, 2003
    Inventors: Michael G. Bramucci, Patricia C. Brzostowicz, Kristy N. Kostichka, Vasantha Nagarajan, Pierre E. Rouviere, Stuart M. Thomas
  • Publication number: 20030113886
    Abstract: Two gene clusters have been isolated from an Brevibacterium sp HCU that encode the enzymes expected to convert cyclohexanol to adipic acid. Individual open reading frames (ORF's) on each gene cluster are useful for the production of intermediates in the adipic acid biosynthetic pathway or of related molecules. All the ORF's have been sequenced. Identification of gene function has been made on the basis of sequence comparison and biochemical analysis.
    Type: Application
    Filed: August 29, 2002
    Publication date: June 19, 2003
    Inventors: Patricia C. Brzostowicz, Pierre E. Rouviere
  • Publication number: 20030003528
    Abstract: A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields.
    Type: Application
    Filed: August 29, 2001
    Publication date: January 2, 2003
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Deana Dicosimo, Mattheos Koffas, Edward S. Miller, James M. Odom, Stephen K. Picataggio, Pierre E. Rouviere
  • Patent number: 6465224
    Abstract: Two gene clusters have been isolated from an Brevibacterium sp HCU that encode the enzymes expected to convert cyclohexanol to adipic acid. Individual open reading frames (ORF's) on each gene cluster are useful for the production of intermediates in the adipic acid biosynthetic pathway or of related molecules. All the ORF's have been sequenced. Identification of gene function has been made on the basis of sequence comparison and biochemical analysis.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: October 15, 2002
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Patricia C. Brzostowicz, Pierre E. Rouviere
  • Publication number: 20020127666
    Abstract: Two gene clusters have been isolated from an Brevibacterium sp HCU that encode the enzymes expected to convert cyclohexanol to adipic acid. Individual open reading frames (ORF's) on each gene cluster are useful for the production of intermediates in the adipic acid biosynthetic pathway or of related molecules. All the ORF's have been sequenced. Identification of gene function has been made on the basis of sequence comparison and biochemical analysis.
    Type: Application
    Filed: September 17, 2001
    Publication date: September 12, 2002
    Inventors: Patricia C. Brzostowicz, Pierre E. Rouviere
  • Patent number: 6365376
    Abstract: Two gene clusters have been isolated from an Brevibacterium sp HCU that encode the enzymes expected to convert cyclohexanol to adipic acid. Individual open reading frames (ORF's) on each gene cluster are useful for the production of intermediates in the adipic acid biosynthetic pathway or of related molecules. All the ORF's have been sequenced. Identification of gene function has been made on the basis of sequence comparison and biochemical analysis.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: April 2, 2002
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Patricia C. Brzostowicz, Pierre E. Rouviere