Patents by Inventor Patricia Ducy

Patricia Ducy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for control of bone formation via modulation of leptin activity
    Publication number: 20040202652
    Abstract: The invention relates to the method for treatment, diagnosis and prevention of bone disease and comprises methods including inhibiting or increasing leptin synthesis, leptin receptor synthesis, leptin binding to the leptin receptor, and leptin receptor activity. The invention also relates to screening assays to identify compounds that modulate leptin and/or leptin receptor activity. The invention further relates to gene therapy methods utilizing leptin and leptin-related sequences for the treatment and prevention of bone disease.
    Type: Application
    Filed: April 22, 2004
    Publication date: October 14, 2004
    Applicants: Baylor College of Medicine
    Inventors: Gerard Karsenty, Patricia Ducy, Michael Amling
  • Methods and compositions for control of bone formation via modulation of neuropeptide Y activity
    Publication number: 20040127440
    Abstract: The invention relates to the method for treatment, diagnosis and prevention of bone disease and comprises methods including inhibiting or increasing neuropeptide Y synthesis, neuropeptide Y receptor synthesis, neuropeptide Y binding to the neuropeptide Y receptor, and neuropeptide Y receptor activity. The invention also relates to screening assays to identify compounds that modulate neuropeptide Y and/or neuropeptide Y receptor activity. The invention further relates to gene therapy methods utilizing neuropeptide Y and neuropeptide Y-related sequences for the treatment and prevention of bone disease.
    Type: Application
    Filed: June 17, 2003
    Publication date: July 1, 2004
    Applicant: BAYLOR COLLEGE OF MEDICINE
    Inventors: Gerard Karsenty, Patricia Ducy, Michael Amling
  • Methods and compositions for control of bone formation via modulation of neuropeptide y activity
    Publication number: 20040053864
    Abstract: The invention relates to the method for treatment, diagnosis and prevention of bone disease and comprises methods including inhibiting or increasing neuropeptide Y synthesis, neuropeptide Y receptor synthesis, neuropeptide Y binding to the neuropeptide Y receptor, and neuropeptide Y receptor activity. The invention also relates to screening assays to identify compounds that modulate neuropeptide Y and/or neuropeptide Y receptor activity. The invention further relates to gene therapy methods utilizing neuropeptide Y and neuropeptide Y-related sequences for the treatment and prevention of bone disease.
    Type: Application
    Filed: November 13, 2002
    Publication date: March 18, 2004
    Inventors: Gerard Karsenty, Patricia Ducy, Michael Amling
  • Osf2/Cbfa1 nucleic acids and methods of use therefor
    Patent number: 6518063
    Abstract: Disclosed are methods and compositions comprising a novel osteoblast-specific transcription factor designated Osf2/Cbfa1. Also disclosed are nucleic acid segments encoding this polypeptide derived from human cell lines, and the use of these polynucleotides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of osteoblast differentiation, and identifying Osf2/Cbfa1 polynucleotides and polypeptides in a sample. Also disclosed are nucleic acid compositions comprising an Osf2 promoter, and the use of the promoter in heterologous and homologous gene transcription and protein production.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: February 11, 2003
    Assignee: Board of Regents, The University of Texas System
    Inventors: Patricia Ducy, Gérard Karsenty