Abstract: A P2Et treatment using a casein nanoencapsulation method for significantly delaying tumor growth. The nanoencapeulation leads to higher doses of effective P2Et being delivered, improving bioavailability and biological activity and as such, provides a novel perspective on the delivery of these functional ingredients.

Abstract: The present invention relates to a novel class of pyridine-sulfonamide compounds and to compositions comprising the same. The compounds and compositions are useful as medicaments in the treatment of diseases responsive to inhibition of IL-1?, such as non-alcoholic steatohepatitis (NASH) and idiopathic pulmonary fibrosis (IPF).

Abstract: A method is provided for changing and recovering personalization data of a trusted software in a secure element and changing and restoring diversified data. The method includes the steps of providing an update agent in the secure element; storing personalization data in the installed software; performing a Full Reflash to recover or update a software or operating system comprising the steps of first securing personalization data to a memory of the update agent before, in following step, recovering or loading a software image into the secure element. The method includes as a final step personalizing the software image by the personalization data secured during the first step of the Full Reflash.

Abstract: A method for the treatment of wastewaters including a cyanide compound and a metallic compound, wherein the wastewaters are subjected to a single oxidation step during which cyanides compounds are converted into carbon dioxide and nitrogen, this oxidation step including the mixing of wastewaters with a chlorine solution and an alkaline agent so as to obtain a mixture, the alkaline agent being added in such a quantity so as to maintain the pH of said mixture between 8.8 and 9.5 and the chlorine solution being added in such a quantity so as to maintain the oxydo-reduction potential of the mixture between 150 and 450 mV.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: A hob device includes a plate unit including a plate main body, which has a plate side with an at least substantially smooth surface in a surface portion, a first layer unit arranged in a first sub-region of the surface portion and being at least substantially non-transparent, and a second layer unit arranged in a second sub-region of the surface portion and designed to scatter light.

Abstract: A hob apparatus includes a heating region for placement and heating of a cooking container. A dynamic display unit provides an identification of the heating region in an operating mode, and a control unit selects an identifying property of the identification of the heating region in the operating mode, depending on an operating parameter.

Abstract: The present invention relates to a novel class of pyridine-sulfonamide compounds and to compositions comprising the same. The compounds and compositions are useful as medicaments in the treatment of diseases responsive to inhibition of IL-1?, such as non-alcoholic steatohepatitis (NASH) and idiopathic pulmonary fibrosis (IPF).

Abstract: A cooking device includes a light unit and an insulation unit configured to electrically insulate the light unit. The insulation unit includes a first insulation element and a second insulation element, with the light unit being at least partially arranged between the first insulation element and the second insulation element.

Abstract: A method for the treatment of wastewaters including a cyanide compound and a metallic compound, wherein the-wastewaters are subjected to a single oxidation step during which cyanides compounds are converted into carbon dioxide and nitrogen, this oxidation step including the mixing of wastewaters with a chlorine solution and an alkaline agent so as to obtain a mixture, the alkaline agent being added in such a quantity so as to maintain the pH of said mixture between 8.8 and 9.5 and the chlorine solution being added in such a quantity so as to maintain the oxydo-reduction potential of the mixture between 150 and 450 mV.

Abstract: The invention relates to an unspecific peroxygenase of the Agrocybe aegerita fungus, obtained by means of directed molecular evolution to facilitate the functional expression thereof in an active, soluble and stable form. The peroxygenase described in the invention shows a significant improvement in the functional expression thereof, improved monooxygenase activity and reduced peroxidase activity, in relation to the monooxygenase and peroxidase activities showed by the unspecific wild-type peroxygenase of A. aegerita. The peroxygenase of the invention is useful in chemical processes, including industrial transformations such as the selective oxyfunctionalisation of carbon-hydrogen bonds of various organic compounds.

Abstract: The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

Abstract: A cooking device includes a light unit and an insulation unit configured to electrically insulate the light unit. The insulation unit includes a first insulation element and a second insulation element, with the light unit being at least partially arranged between the first insulation element and the second insulation element.

Abstract: The invention relates to an unspecific peroxygenase of the Agrocybe aegerita fungus, obtained by means of directed molecular evolution to facilitate the functional expression thereof in an active, soluble and stable form. The peroxygenase described in the invention shows a significant improvement in the functional expression thereof, improved monooxygenase activity and reduced peroxidase activity, in relation to the monooxygenase and peroxidase activities showed by the unspecific wild-type peroxygenase of A. aegerita. The peroxygenase of the invention is useful in chemical processes, including industrial transformations such as the selective oxyfunctionalisation of carbon-hydrogen bonds of various organic compounds.

Abstract: A hob apparatus includes a heating region for placement and heating of a cooking container. A dynamic display unit provides an identification of the heating region in an operating mode, and a control unit selects an identifying property of the identification of the heating region in the operating mode, depending on an operating parameter.

Abstract: p38 and JNK mitogen activated protein (MAP) kinase al losteric inhibitors are useful for treatment and/or prophylaxis of degenerative diseases of the nervous system. Compounds are used in a method for treatment and/or prophylaxis of the diseases and for use in therapy in general. The compounds bind to the region composed of amino acids at positions 170-199 of Mitogen-activated protein kinase 14 (Uniprot accession nr Q16539 or SEQ ID No 1) and/or Mitogen-activated protein kinase 11 (Uniprot accession nr Q15759 or SEQ ID No 2), SEQ ID NO.1 and SEQ ID NO.2 being the amino acid sequences of MAPK14 (?38?) and MAPK11 (?38?), respectively. The specific region composed of amino acids at positions 170-199 is herein disclosed as SEQ ID HO.4 for Mitogen-activated protein kinase 14 and SEQ ID NO.5 for Mitogen-activated protein kinase 11 and are believed to be new inhibitory binding sites.

Abstract: A new and distinct cultivar of Aechmea plant named ‘Del Cielo’, characterized by its upright and outwardly arching growth habit; creamy white, light green and green variegated leaves with green-colored margins and creamy white and yellow green-colored longitudinal stripes; inflorescences held upright and above the foliar plane on strong red-colored scapes; tightly branched inflorescences with dark violet blue-colored petals and lighter violet blue-colored sepals; and long-lasting inflorescences.

Abstract: A new and distinct cultivar of Aechmea plant named ‘Patricia's Secret’, characterized by its upright and outwardly arching growth habit; unique yellow green and green variegated leaves with green-colored margins and yellow green-colored longitudinal stripes with a rosy pink-colored blush; inflorescences held upright and above the foliar plane on strong orange-colored scapes; tightly branched inflorescences with greyed orange-colored flower bracts with greyed yellow-colored sepals; and long-lasting inflorescences.

Abstract: A new and distinct cultivar of Aechmea plant named ‘Del Cielo’, characterized by its upright and outwardly arching growth habit; creamy white, light green and green variegated leaves with green-colored margins and creamy white and yellow green-colored longitudinal stripes; inflorescences held upright and above the foliar plane on strong red-colored scapes; tightly branched inflorescences with dark violet blue-colored petals and lighter violet blue-colored sepals; and long-lasting inflorescences.