Patents by Inventor Patricia Gizecki

Patricia Gizecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enantioselective preparation of sulphoxide derivatives
    Patent number: 7528251
    Abstract: The present invention concerns enantioselective preparation of sulphoxide derivatives or their salts. The method consist in performing an enantioselective oxidation of a sulphur of general formula (I) A —CH2—SB, wherein: A is a diversely substituted pyridinyl ring and B is a heterocyclic radical comprising an imidazo-pyridinyl ring, using an oxidizing agent in the presence of a titanium (IV)-based catalyst and a chiral ligand consisting of a cyclic beta or gamma-amino-alcohol, in an organic solvent, followed, if required, by salt formation with a base. The invention is useful for preparing sulphoxides useful in therapeutics.
    Type: Grant
    Filed: October 5, 2005
    Date of Patent: May 5, 2009
    Assignee: Sidem Pharma SA
    Inventors: Avraham Cohen, Suzy Charbit, François Schutze, Frédéric Martinet, Patricia Gizecki
  • Method For Enantioselective Preparation Of Sulphoxide Derivatives
    Publication number: 20070299261
    Abstract: The present invention concerns enantioselective preparation of sulphoxide derivatives or their salts. The method consist in performing an enantioselective oxidation of a sulphur of general formula (I) A-CH2—SB, wherein: A is a diversely substituted pyridinyl ring and B is a heterocyclic radical comprising an imidazo-pyridinyl ring, using an oxidizing agent in the presence of a titanium (IV)-based catalyst and a chiral ligand consisting of a cyclic beta or gamma-amino-alcohol, in an organic solvent, followed, if required, by salt formation with a base. The invention is useful for preparing sulphoxides useful in therapeutics.
    Type: Application
    Filed: October 5, 2005
    Publication date: December 27, 2007
    Applicant: SIDEM PHARMA SA
    Inventors: Avraham Cohen, Suzy Charbit, Francois Schutze, Frederic Martinet, Patricia Gizecki