Patents by Inventor Patricia MacLeod

Patricia MacLeod has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and intermediates for preparing integrase inhibitors
    Patent number: 8877931
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: November 4, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Dominika Pcion, Carrie Tomasi, Mark Charles Whitcomb, Eric D. Dowdy, Wenyi Fu, Patricia MacLeod
  • PROCESS AND INTERMEDIATES FOR PREPARING INTEGRASE INHIBITORS
    Publication number: 20140039194
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Dominika PCION, Carrie TOMASI, Mark Charles WHITCOMB, Eric D. DOWDY, Wenyi FU, Patricia MACLEOD
  • Chiral ligands, their preparation and uses thereof in asymmetric reactions
    Patent number: 8232399
    Abstract: A novel class of chiral ligands represented by a structure of Formula I: wherein R1, R2, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C1-10 alkoxy, C(O)R6, C(O)NHR6, Si(R6)3, benzyl and aryl; X is selected from the group consisting of OH, OR7, O-Prot and P(R7)2 where Prot represents a protecting group; and R6 and R7 are selected from the group consisting of hydrogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C1-10 alkoxy, phenyl, and aryl is disclosed herein.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: July 31, 2012
    Inventors: Chao-Jun Li, Patricia MacLeod, Zhiping Li, Jianqing Feng
  • CHIRAL LIGANDS, THEIR PREPARATION AND USES THEREOF IN ASYMMETRIC REACTIONS
    Publication number: 20090306390
    Abstract: A novel class of chiral ligands represented by a structure of Formula (I): wherein R1, R2, R3, R4 and R5 are independently selected from the group consisting of hydrogen, halogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C1-10 alkoxy, C(O)R6, C(O)NHR6, Si(R6)3, benzyl and aryl; X is selected from the group consisting of OH, OR7, O-Prot and P(R7)2 where Prot represents a protecting group; and R6 and R7 are selected from the group consisting of hydrogen, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, C1-10 alkoxy, phenyl, and aryl is disclosed herein.
    Type: Application
    Filed: March 2, 2007
    Publication date: December 10, 2009
    Applicant: Chao-Jun Li
    Inventors: Chao-Jun Li, Patricia MacLeod, Zhiping Li, Jianqing Feng