Patents by Inventor Patricia R. Segarini

Patricia R. Segarini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • &agr;2-macroglobulin receptor as a receptor for CTGF
    Patent number: 6555322
    Abstract: The invention provides a connective tissue growth factor (CTGF) receptor and biochemical and/or biological equivalents, homologs, derivatives, subunits, fragments, and complexes thereof. The CTGF receptor is useful in the treatment and diagnosis of CTGF-associated disorders and in methods of screening for agents that effect CTGF receptor expression and activity. The invention further provides nucleic acid sequences encoding the CTGF receptor, recombinant DNA molecules comprising these sequences, and transformed hosts carrying the recombinant DNA molecules, antisense sequences and antibodies directed against CTGF receptor, and pharmaceutical compositions for use in treatment of CTGF-associated disorders.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: April 29, 2003
    Assignee: FibroGen, Inc.
    Inventors: Patricia R. Segarini, James E. Nesbitt, David F. Carmichael
  • Uses of TGF-.beta. receptor fragment as a therapeutic agent
    Patent number: 5693607
    Abstract: A method of treating TGF-.beta. excess is disclosed. The treatment is parenteral, oral or topical administration of TGF-.beta. receptor fragment. Particularly effective is a soluble receptor fragment which resembles the extracellular portion of TGF-.beta. binding protein II.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: December 2, 1997
    Inventors: Patricia R. Segarini, James R. Dasch, David R. Olsen, Pedro A. Carrillo, Desmond Mascarenhas