Patents by Inventor Patricia Sansilvestri-Morel

Patricia Sansilvestri-Morel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10654878
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, —N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: May 19, 2020
    Assignee: LES LABORATOIRES SERVIER
    Inventors: Philippe Gloanec, Arnaud-Pierre Schaffner, Patricia Sansilvestri-Morel, Alain Rupin, Philippe Mennecier, Marie-Odile Vallez
  • Publication number: 20190031693
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Application
    Filed: October 4, 2018
    Publication date: January 31, 2019
    Inventors: Philippe GLOANEC, Arnaud-Pierre SCHAFFNER, Patricia SANSILVESTRI-MOREL, Alain RUPIN, Philippe MENNECIER, Marie-Odile VALLEZ
  • Patent number: 10138260
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, —N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: November 27, 2018
    Assignee: LES LABORATOIRES SERVIER
    Inventors: Philippe Gloanec, Arnaud-Pierre Schaffner, Patricia Sansilvestri-Morel, Alain Rupin, Philippe Mennecier, Marie-Odile Vallez
  • Publication number: 20180016288
    Abstract: Compounds of formula (I) wherein: Ak1 represents an alkyl chain, X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)—, —N(R)—CH2— or —CH2—N(R)—CH2—, m and R are as defined in the description, R1 and R2 each represent H when X represents —(CH2)m—, —CH(R)—, —N(R)—, —CH2—N(R)— or —N(R)—CH2—, or together form a bond when X represents —CH2—N(R)—CH2—, R3 represents NH2, Cy-NH2, Cy-Ak3-NH2 or piperidin-4-yl, Cy and Ak3 are as defined in the description, R4 and R5, which may be identical or different, each represent H or F, their optical isomers, and addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating conditions requiring a TAFIa inhibitor.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 18, 2018
    Inventors: Philippe GLOANEC, Arnaud-Pierre SCHAFFNER, Patricia SANSILVESTRI-MOREL, Alain RUPIN, Philippe MENNECIER, Marie-Odile VALLEZ
  • Patent number: 8404742
    Abstract: Compounds of formula (I): wherein R1, R2 and R3, which may be the same or different, each represent a hydrogen atom or the group of formula (A): Medicinal products containing the same which are useful in the prevention and/or treatment of venous diseases and other conditions.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: March 26, 2013
    Assignee: Les Laboratories Server
    Inventors: Michel Wierzbicki, Marie-Francoise Boussard, Tony Verbeuren, Patricia Sansilvestri-Morel, Alain Rupin, Jérôme Paysant, François Lefoulon
  • Publication number: 20120208777
    Abstract: Compounds of formula (I): wherein R1, R2 and R3, which may be the same or different, each represent a hydrogen atom or the group of formula (A): Medicinal products containing the same which are useful in the prevention and/or treatment of venous diseases and other conditions.
    Type: Application
    Filed: February 14, 2012
    Publication date: August 16, 2012
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Michel WIERZBICKI, Marie-Françoise BOUSSARD, Tony VERBEUREN, Patricia SANSILVESTRI-MOREL, Alain RUPIN, Jérôme PAYSANT, François LEFOULON
  • Patent number: 8138223
    Abstract: Compounds of formula (I): wherein R1, R2 and R3, which may be the same or different, each represent a hydrogen atom or the group of formula (A): Medicinal products containing the same which are useful in the prevention and/or treatment of venous diseases and other conditions.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: March 20, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Michel Wierzbicki, Marie-Françoise Boussard, Tony Verbeuren, Patricia Sansilvestri-Morel, Alain Rupin, Jérôme Paysant, François Lefoulon
  • Publication number: 20090247621
    Abstract: Compounds of formula (I): wherein R1, R2 and R3, which may be the same or different, each represent a hydrogen atom or the group of formula (A): Medicinal products containing the same which are useful in the prevention and/or treatment of venous diseases and other conditions.
    Type: Application
    Filed: March 30, 2009
    Publication date: October 1, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Michel Wierzbicki, Marie-Francoise Boussard, Tony Verbeuren, Patricia Sansilvestri-Morel, Alain Rupin, Jerome Paysant, Francois Lefoulon
  • Publication number: 20090075976
    Abstract: The present invention relates to the association of an anti-atherothrombotic and an angiotensin-converting enzyme inhibitor (ACEI), and also to pharmaceutical compositions containing them, and to methods of treating vascular complications associated with diabetes, with atherothrombotic diseases, with hyperlipidaemia, with hypertension, with chronic venous diseases, with inflammation, with metabolic syndrome associated with obesity, or with cancer, with such association.
    Type: Application
    Filed: September 8, 2008
    Publication date: March 19, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Tony Verbeuren, Patricia Sansilvestri-Morel, Alain Rupin, Marie-Odile Vallez, Marie-Dominique Fratacci, Laurence Lerond, Gilbert Lavielle
  • Publication number: 20080176934
    Abstract: Use of diosmetin compounds in obtaining pharmaceutical compositions intended for the prevention and/or treatment of thrombotic pathologies and pathologies with a risk of thrombosis.
    Type: Application
    Filed: February 28, 2006
    Publication date: July 24, 2008
    Applicant: Les Laboratoires Servier
    Inventors: Tony Verbeuren, Alain Rupin, Patricia Sansilvestri-Morel, Marie-Odile Vallez, Marie-Francoise Boussard, Michel Wierzbicki