Patents by Inventor Patricia Sepulcri

Patricia Sepulcri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assaying the teichoic acids of grambacteria
    Patent number: 7320874
    Abstract: The invention relates to a method for assaying the teichoic acids present, most commonly in residual form, in a preparation of Gram+ bacterial antigens. This method requires, first of all, a controlled hydrolysis with hydrofluoric acid at a temperature of less than or equal to 40° C., in order to release the oligosaccharides specific for teichoic acids. The assaying of the specific oligosaccharides can then be carried out by various techniques, in particular by high performance chromatography coupled with pulsed amperometric detection (HPAEC-PAD). The method according to the invention can in particular be used to assay the residual amounts of teichoic acids present in preparations containing capsular polysaccharides of Streptococcus pneumoniae, which may be useful as vaccines.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: January 22, 2008
    Assignee: Aventis Pasteur SA
    Inventors: Philippe Talaga, Patricia Sepulcri, Sandrine Vialle-Blanc
  • Assaying the teichoic acids of gram+ bacteria
    Publication number: 20050009121
    Abstract: The invention relates to a method for assaying the teichoic acids present, most commonly in residual form, in a preparation of Gram+ bacterial antigens. This method requires, first of all, a controlled hydrolysis with hydrofluoric acid at a temperature of less than or equal to 40° C., in order to release the oligosaccharides specific for teichoic acids. The assaying of the specific oligosaccharides can then be carried out by various techniques, in particular by high performance chromatography coupled with pulsed amperometric detection (HPAEC-PAD). The method according to the invention can in particular be used to assay the residual amounts of teichoic acids present in preparations containing capsular polysaccharides of Streptococcus pneumoniae, which may be useful as vaccines.
    Type: Application
    Filed: July 6, 2004
    Publication date: January 13, 2005
    Inventors: Philippe Talaga, Patricia Sepulcri, Sandrine Vialle-Blanc