Patents by Inventor Patricia T. W. Cohen

Patricia T. W. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein phosphatase 1 binding protein, R5
    Patent number: 6297359
    Abstract: Human PPP1R5 polypeptides and DNA (RNA) encoding such PPP1R5 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such PPP1R5, or compounds which inhibit or stimulate PPP1R5 for dysfunctions or diseases which involve resistance to the action of insulin on glycogen synthesis are also disclosed. Agonist and antagonists of these PPP1R5 proteins and methods of their use are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the PPP1R5 and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: October 2, 2001
    Assignee: SmithKline Beecham Corporation, et al.
    Inventors: Peter R. Young, Patricia T. W. Cohen, Phillip Cohen
  • Protein phosphatase 1 binding protein, R5
    Patent number: 5939284
    Abstract: Human PPP1R5 polypeptides and DNA (RNA) encoding such PPP1R5 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such PPP1R5, or compounds which inhibit or stimulate PPP1R5 for dysfunctions or diseases which involve resistance to the action of insulin on glycogen synthesis are also disclosed. Agonist and antagonists of these PPP1R5 proteins and methods of their use are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the PPP1R5 and for detecting altered levels of the polypeptide in a host.
    Type: Grant
    Filed: December 5, 1996
    Date of Patent: August 17, 1999
    Assignee: Smithkline Beecham Corporation
    Inventors: Patricia T. W. Cohen, Phillip Cohen, Peter R. Young