Patents by Inventor Patricia Vrinten
Patricia Vrinten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11952581Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: GrantFiled: November 22, 2021Date of Patent: April 9, 2024Assignee: BASF PLANT SCIENCE GMBHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20230293615Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.Type: ApplicationFiled: January 31, 2023Publication date: September 21, 2023Inventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
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Publication number: 20230183728Abstract: The present invention is concerned with materials and methods for the production of genetically modified plants, particularly where the plants are for the production of at least one unsaturated or polyunsaturated fatty acid. The invention is also concerned with identification of genes conveying an unsaturated fatty acid metabolic property to a plant or plant cell, and generally relates to the field of phosphotidylcholine:diacylglycerol cholinephosphotransferase (PDCT).Type: ApplicationFiled: September 6, 2019Publication date: June 15, 2023Inventors: Toralf Senger, Hui Yang, Carl Andre, Patricia Vrinten
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Patent number: 11613761Abstract: T-DNA for expression of a target gene in a plant, wherein the T-DNA comprises a left and a right border element and at least one expression cassette comprising a promoter, operatively linked thereto a target gene, and downstream thereof a terminator, wherein the length of the T-DNA, measured from left to right border element and comprising the target gene, has a length of at least 30000 bp.Type: GrantFiled: November 13, 2015Date of Patent: March 28, 2023Assignees: Bioriginal Food & Science Corporation, BASF Plant Science Company GmbHInventors: Toralf Senger, Laurent Marty, Irene Kunze, Heiko Haertel, Steven Craig Bremmer, Steven D. Breazeale, Joerg Bauer, Patricia Vrinten, Sten Stymne, Jenny Lindberg Yilmaz, John A. McElver, Dietrich Rein, Carl Andre
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Publication number: 20220162629Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: November 22, 2021Publication date: May 26, 2022Inventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20220025391Abstract: The present invention is concerned with materials and methods for the production of genetically modified plants, particularly where the plants are for the production of at least one unsaturated or polyunsaturated fatty acid. The invention is also concerned with identification of genes conveying an unsaturated fatty acid metabolic property to a plant or plant cell, and generally relates to the field of phosphotidylcholine:diacylglycerol cholinephosphotransferase (PDCT).Type: ApplicationFiled: September 6, 2019Publication date: January 27, 2022Inventors: Toralf Senger, Hui Yang, Patricia Vrinten, Carl Andre
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Patent number: 11180769Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: GrantFiled: July 11, 2019Date of Patent: November 23, 2021Assignee: BASF PLANT SCIENCE GMBHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Schmidt, Helene Kirsch
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Publication number: 20210317467Abstract: The present invention is concerned with materials and methods for the production of genetically modified plants, particularly where the plants are for the production of at least one unsaturated or polyunsaturated fatty acid. The invention is also concerned with identification of genes conveying an unsaturated fatty acid metabolic property to a plant or plant cell, and generally relates to the field of phosphotidylcholine:diacylglycerol cholinephosphotransferase (PDCT).Type: ApplicationFiled: September 6, 2019Publication date: October 14, 2021Inventors: Toralf Senger, Hui Yang, Carl Andre, Patricia Vrinten
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Patent number: 11046937Abstract: The present invention relates to methods for the conversion of the substrate specificity of desaturases. Specifically, the present invention pertains to a method for the conversion of the substrate specificity of a ?5 and/or ?6 desaturase to the substrate specificity of a ?4 desaturase, the method comprising: identifying regions and/or amino acid residues which control the substrate specificity of (i) the ?5 and/or ?6 desaturase and (ii) the ?4 desaturase; and replacing in the amino acid sequence of the mentioned ?5 and/or ?6 desaturase, the regions and/or amino acid residues which control the substrate specificity of the ?5 and/or ?6 desaturase, by the corresponding regions and/or amino acid residues which control the substrate specificity of the ?4 desaturase, thereby converting the substrate specificity of the ?5 and/or ?6 desaturase to the substrate specificity of the ?4 desaturase.Type: GrantFiled: May 16, 2019Date of Patent: June 29, 2021Assignees: BASF PLANT SCIENCE COMPANY GMBH, Bioriginal Food & Science Corp.Inventors: Toralf Senger, Patricia Vrinten, Ze Long Lim
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Publication number: 20190323024Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: July 11, 2019Publication date: October 24, 2019Inventors: Thorsten ZANK, Jörg BAUER, Petra CIRPUS, Amine ABBADI, Ernst HEINZ, Xiao QIU, Patricia VRINTEN, Petra SPERLING, Frederic DOMERGUE, Astrid SCHMIDT, Helene KIRSCH
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Publication number: 20190270972Abstract: The present invention relates to methods for the conversion of the substrate specificity of desaturases. Specifically, the present invention pertains to a method for the conversion of the substrate specificity of a ?5 and/or ?6 desaturase to the substrate specificity of a ?4 desaturase, the method comprising: identifying regions and/or amino acid residues which control the substrate specificity of (i) the ?5 and/or ?6 desaturase and (ii) the ?4 desaturase; and replacing in the amino acid sequence of the mentioned ?5 and/or ?6 desaturase, the regions and/or amino acid residues which control the substrate specificity of the ?5 and/or ?6 desaturase, by the corresponding regions and/or amino acid residues which control the substrate specificity of the ?4 desaturase, thereby converting the substrate specificity of the ?5 and/or ?6 desaturase to the substrate specificity of the ?4 desaturase.Type: ApplicationFiled: May 16, 2019Publication date: September 5, 2019Inventors: Toralf Senger, Patricia Vrinten, Ze Long Lim
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Patent number: 10329541Abstract: The present invention relates to methods for the conversion of the substrate specificity of desaturases. Specifically, the present invention pertains to a method for the conversion of the substrate specificity of a ?5 and/or ?6 desaturase to the substrate specificity of a ?4 desaturase, the method comprising: identifying regions and/or amino acid residues which control the substrate specificity of (i) the ?5 and/or ?6 desaturase and (ii) the ?4 desaturase; and replacing in the amino acid sequence of the mentioned ?5 and/or ?6 desaturase, the regions and/or amino acid residues which control the substrate specificity of the ?5 and/or ?6 desaturase, by the corresponding regions and/or amino acid residues which control the substrate specificity of the ?4 desaturase, thereby converting the substrate specificity of the ?5 and/or ?6 desaturase to the substrate specificity of the ?4 desaturase.Type: GrantFiled: December 17, 2014Date of Patent: June 25, 2019Assignees: BASF PLANT SCIENCE COMPANY GMBH, BIORIGINAL FOOD & SCIENCE CORP.Inventors: Toralf Senger, Patricia Vrinten, Ze Long Lim
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Publication number: 20170298380Abstract: The present disclosure provides borage plants having increased resistance to imidazolinone herbicides. More particularly, provided herein are methods for generating herbicide resistant borage and testing of selected progeny for homozygosity. Nucleic acids encoding AHAS 1 and 2 genes that encode herbicide resistance in borage are provided.Type: ApplicationFiled: April 13, 2016Publication date: October 19, 2017Applicant: Bioriginal Food & Science Corp.Inventors: Guohai Wu, Dongyan Song, Patricia Vrinten, Xiao Qiu
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Publication number: 20170016015Abstract: The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with ?5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism. Especially advantageous are nucleic acids which encode ?6-desaturases, ?5-desaturases, ?4-desaturases and/or ?6-elongases. These desaturases and elongases are advantageously derived from Thalassiosira, Euglena or Ostreococcus. The invention furthermore relates to a process for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids, and oils and/or triacylglycerides thus obtained.Type: ApplicationFiled: August 16, 2016Publication date: January 19, 2017Inventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Publication number: 20160319249Abstract: The present invention relates to methods for the conversion of the substrate specificity of desaturases. Specifically, the present invention pertains to a method for the conversion of the substrate specificity of a ?5 and/or ?6 desaturase to the substrate specificity of a ?4 desaturase, the method comprising: identifying regions and/or amino acid residues which control the substrate specificity of (i) the ?5 and/or ?6 desaturase and (ii) the ?4 desaturase; and replacing in the amino acid sequence of the mentioned ?5 and/or ?6 desaturase, the regions and/or amino acid residues which control the substrate specificity of the ?5 and/or ?6 desaturase, by the corresponding regions and/or amino acid residues which control the substrate specificity of the ?4 desaturase, thereby converting the substrate specificity of the ?5 and/or ?6 desaturase to the substrate specificity of the ?4 desaturase.Type: ApplicationFiled: December 17, 2014Publication date: November 3, 2016Inventors: Toralf Senger, Patricia Vrinten, Ze Long Lim
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Patent number: 9433228Abstract: The invention relates to a method for the production of multiply-unsaturated fatty acids in an organism, into which nucleic acids have been introduced, which code for polypeptides with ?-5 elongase activity. Said nucleic acid sequences, optionally with further nucleic acid sequences, coding for polypeptides for the biosynthesis of fatty acids and lipid metabolism, are advantageously expressed in the organism. Nucleic acid sequences coding for a ?-6 desaturase, a ?-5 desaturase, ?-4 desaturase and/or ?-6 elongase activity are particularly advantageous and, advantageously, said saturases and elongases are derived from Thalassiosira, Euglena or Ostreococcus. The invention further relates to a method for the production of oils and/or triacylglycerides with an increased content of long-chain, multiply-unsaturated fatty acids.Type: GrantFiled: July 16, 2004Date of Patent: September 6, 2016Assignee: BASF Plant Science GmbHInventors: Thorsten Zank, Jörg Bauer, Petra Cirpus, Amine Abbadi, Ernst Heinz, Xiao Qiu, Patricia Vrinten, Petra Sperling, Frederic Domergue, Astrid Meyer, Jelena Kirsch
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Patent number: 9388436Abstract: The present invention relates to nucleic acids derived from Limonomyces roseipellis. The invention also relates to the individual coding sequences and to proteins encoded by these sequences as well to a process for converting oleic acid to linoleic acid to linoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant.Type: GrantFiled: November 23, 2010Date of Patent: July 12, 2016Assignee: BASF Plant Science Company GmbHInventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Patent number: 9347049Abstract: The present invention relates to nucleic acids derived from Sphaeroforma arctica. The invention also relates to the individual coding sequences and to proteins encoded by these sequences in combination with other sequences as well as to a process for converting oleic acid to linoleic acid to linoleic acid and the production of arachidonic acid, eicosapentaenoic acid and/or docosahexaenoic acid in a plant.Type: GrantFiled: November 23, 2010Date of Patent: May 24, 2016Assignee: BASF Plant Science Company GmbHInventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Patent number: 8901374Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid dehydratase family members. The invention also provides recombinant expression vectors containing dehydratase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., SDA, EPA and DHA.Type: GrantFiled: June 2, 2009Date of Patent: December 2, 2014Assignees: BASF Plant Science GmbH, Bioriginal Food & Science Corp.Inventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Patent number: 8318914Abstract: The present invention relates to polynucleotides from Pythium irregulare, Rhizopus oryzae and Euglena gracilis which code for elongases and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotides according to the invention, and to the polypeptides encoded by the polynucleotides. The invention furthermore relates to antibodies against the polypeptides according to the invention. Finally, the invention also relates to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.Type: GrantFiled: July 30, 2008Date of Patent: November 27, 2012Assignees: Bioriginal Food & Science Corp., BASF Plant Science GmbHInventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten