Patents by Inventor Patricia Vusio

Patricia Vusio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-15RALPHA SUSHI DOMAIN - IL-15 FUSION PROTEINS
    Publication number: 20200109184
    Abstract: The present invention relates to the stimulation of the IL-15Rbeta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells. Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.
    Type: Application
    Filed: June 13, 2019
    Publication date: April 9, 2020
    Inventors: Yannick Jacques, Ariane Plet, Erwan Mortier, Agnès Quemener, Patricia Vusio
  • IL-15Ralpha sushi domain—IL-15 fusion proteins
    Patent number: 10358477
    Abstract: The present invention relates to the stimulation of the IL-15Rbeta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells. Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: July 23, 2019
    Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Yannick Jacques, Ariane Plet, Erwan Mortier, Agnes Quemener, Patricia Vusio
  • IL-15RALPHA SUSHI DOMAIN AS A SELECTIVE AND POTENT ENHANCER OF IL-15 ACTION THROUGH IL-15BETA/GAMMA, AND HYPERAGONIST (IL-15RALPHA SUSHI - IL-15) FUSION PROTEINS
    Publication number: 20090238791
    Abstract: The present invention relates to the stimulation of the IL-15R beta/gamma signalling pathway, to thereby induce and/or stimulate the activation and/or proliferation of IL-15Rbeta/gamma-positive cells, such as NK and/or T cells. Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.
    Type: Application
    Filed: October 6, 2006
    Publication date: September 24, 2009
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Yannick Jacques, Ariane Plet, Erwan Mortier, Agnes Quemener, Patricia Vusio