Abstract: A painless injection apparatus includes a first injector having a first storage chamber storing a numbing agent, a first needle, and a first plunger, and a second injector having a second storage chamber storing a medication, a second needle, and a second plunger. The injection apparatus further includes a plunger actuation device coupled to the first and second plungers and the second storage chamber. The plunger actuation device is adapted to sequentially advance the first plunger, the second storage chamber, and then the second plunger to inject the numbing agent and then the medication painlessly into a patient's tissues at the desired depths. The needles and medicine storage chambers are enclosed in a disposable portion of the injection apparatus which can be disposed of properly.