Abstract: A user of a wireless device, such as a mobile phone, can make purchases or obtain information via a network, such as the Internet, using both voice and non-verbal methods. Users can submit voice queries and receive non-verbal replies, submit non-verbal queries and receive voice replies, or perform similar operations that marry the voice and data capabilities of modern mobile communication devices. The user may provide notification criteria indicating under what conditions a notification should be sent to the user's wireless device. When purchasing opportunities matching the selected notification criteria become available, the user is notified. The user can respond to the notification, and immediately take advantage of the purchasing opportunity if he so desires. Mixed-mode interactions can also be used by sellers to more advantageously control the marketing of distressed, time sensitive, or other merchandise/services.

Abstract: The present invention provides a targeted multi-layered drug delivery system for the delivery of cytotoxic agents to B-cells

Abstract: Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein R represents H, C1-6 alkyl, SO2R1, SO2NR1R2, or COR1; R1 and R2 independently represent C1-6 alkyl; and Ring A represents a phenyl ring or a pyridinyl ring; may be useful in the treatment of anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhoea (primary and secondary), endometriosis, emesis (including motion sickness), intrauterine growth retardation, inflammation (including rheumatoid arthritis), mittlesmerchz, preclampsia, premature ejaculation, premature (preterm) labor and Raynaud's disease.

Abstract: A manual tong is disclosed which includes a continuous composite continuous belt, a handle assembly, and a jaw assembly, where the continuous composite continuous belt is designed to take the place of the convention linked chains used currently in manual tongs. The continuous composite continuous belt is held in place by a set of pins associated with the handle and jaw assemblies. Replacement of the linked chains with the continuous composite continuous belts improve tong safety, improve ease of use, lower cost, make adjustment easier and make continuous belt replacement easier reducing down time and increasing tong utility (one tong can be used for different pipe diameters with a simply adjustment of the continuous belt or a simple replacement of the continuous belt with a different size continuous belt.

Abstract: Compounds of formula (I): or a pharmaceutically acceptable derivative thereof, wherein R represents C1-6alkyl (optionally substituted by C1-6alkyloxy or Het) or C1-6alkyloxy; R1 and R2 independently represent hydrogen, halo or C1-6alkyl, ring A represents Het1; X represents O or NR3; R3 represents hydrogen or C1-6alkyl; ring B represents a phenyl group or Het2, either of which may be optionally substituted with one or more groups selected from halo, CN, C1-6alkyloxy, CF3, C1-6alkyl, NH2 and NO2; Het and Het1 independently represent a 5- or 6-membered saturated, partially unsaturated or aromatic heterocyclic group comprising either (a) 1 to 4 nitrogen atoms, (b) one oxygen or one sulphur atom or (c) 1 oxygen atom or 1 sulphur atoms and 1 or 2 nitrogen atoms are useful for treating anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhoea (primary and secondary), endometriosis, emesis (including motion sickness), intrauterine growth ret

Abstract: Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein: Het represents 2-pyridinyl or 2-pyrimidinyl; R1 represents H, C1-3 alkyl or a nitrogen-containing heterocyclic ring having 5 or 6 ring atoms; R2 represents H, benzyl or C1-3 alkyl; and R3 represents H, methyl, methoxy or chloro; are useful for treating anxiety, cardiovascular disease (including angina, atherosclerosis, hypertension, heart failure, edema, hypernatremia), dysmenorrhoea (primary and secondary), endometriosis, emesis (motion sickness), intrauterine growth retardation, inflammation (including rheumatoid arthritis), mittlesmerchz, preclampsia, premature ejaculation, premature (preterm) labor and Raynaud's disease.

Abstract: A method for facilitating a wireless transaction includes receiving, by a transaction management system, a transaction request and a spoken authentication code from a transaction requester. After authenticating the spoken authentication code, a transaction code is communicated from the transaction management system to a wireless communication device. The transaction code is then optically scanned from a visual display of the wireless communication device.

Abstract: Compounds of formula (I), or a pharmaceutically acceptable derivative thereof, wherein R1 and R3 independently represent H, C1-6alkyl, C3-8cycloalkyl, or halogen; R2 represents C1-6alkyl, CF3 or aryl; a represents 1 or 2; R4, R5, R7 and R8 independently represent H, C1-6alkyl, C1-6alkyloxy, CN or halogen, or R4 and R5, or R7 and R8, together with the ring to which they are attached form an aryl or heterocyclic fused ring system; X represents C or N; Y represents CH2 or O; R6 represents H, CN or halo provided that, when X represents N, R6 is absent. The compounds are useful for treating endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.

Abstract: A method for facilitating a wireless transaction includes receiving, by a transaction fulfillment system, a transaction request from a transaction requester and verifying an identity of the transaction requester. After verifying the identity of the transaction requester, a transaction code is communicated from the transaction fulfillment system to a wireless communication device. After receiving the transaction code, the transaction code is optically scanned from a visual display of the wireless communication device by the transaction fulfillment system.

Abstract: The present invention is directed to methods for immobilizing molecules on siliceous and metallic surfaces. Molecules are immobilized on siliceous or metallic surfaces by stable covalent linkages that are capable of withstanding prolonged use and elevated temperatures. Further, the methods of the present invention describe less-complicated chemistries for the immobilization of molecules that will benefit the reproducibility, efficiency and effectiveness of applications in sensing, chromatography, medical diagnostics and related areas where specific recognition between immobilized and free molecules provides diagnostic information or serves as part of a purification or separations process.

Abstract: A dental handpiece is provided with a collar that moves along an outer surface of the handpiece. A contact is secured to the collar. The collar interfaces with an electrical circuit that extends within the dental handpiece. The contact is removable from the collar and the contact defines an electrical connection between a cutting tool used with the dental handpiece and the electrical circuit that extends within the dental handpiece.

Abstract: A compound of formula (I), or a pharmaceutically acceptable derivative, wherein A, B, V, W, X, Y, and Z are as defined herein; pharmaceutical compositions thereof; and uses thereof.

Abstract: A user of a wireless device, such as a mobile phone, can make purchases or obtain information via a network, such as the Internet, using both voice and non-verbal methods. Users can submit voice queries and receive non-verbal replies, submit non-verbal queries and receive voice replies, or perform similar operations that marry the voice and data capabilities of modern mobile communication devices. The user may provide notification criteria indicating under what conditions a notification should be sent to the user's wireless device. When purchasing opportunities matching the selected notification criteria become available, the user is notified. The user can respond to the notification, and immediately take advantage of the purchasing opportunity if he so desires. Mixed-mode interactions can also be used by sellers to more advantageously control the marketing of distressed, time sensitive, or other merchandise/services.

Abstract: A compact package for a garment made from a delicate material includes a container body having a volume of less than 10 in3 (164 cm3), a delicate material garment, a cover member and a cap. The cover member is inserted into the container body atop the garment, followed by the cap. Preferably, a buffer material is arranged between the garment and the cover member within the container body to protect the garment from damage during the packing process. The package is preferably produced by directing the garment and buffer material into a pre-loading tube, followed by shifting of a plunger member to load the container body with the garment, buffer material and the cover member. Subsequently, the cap is snap-fit upon the container body.

Abstract: A user of a wireless device, such as a mobile phone, can make purchases or obtain information via a network, such as the Internet, using both voice and non-verbal methods. Users can submit voice queries and receive non-verbal replies, submit non-verbal queries and receive voice replies, or perform similar operations that marry the voice and data capabilities of modern mobile communication devices. The user may provide notification criteria indicating under what conditions a notification should be sent to the user's wireless device. When purchasing opportunities matching the selected notification criteria become available, the user is notified. The user can respond to the notification, and immediately take advantage of the purchasing opportunity if he so desires. Mixed-mode interactions can also be used by sellers to more advantageously control the marketing of distressed, time sensitive, or other merchandise/services.

Abstract: Compounds of formula (I), or pharmaceutically acceptable derivatives thereof, wherein: X represents —[CH2]a—R or —[CH2]a—O—[CH2]b—R; a represents a number selected from 0 to 6; b represents a number selected from 0 to 6; R represents H, CF3 or Het; Het represents an optionally substituted 5- or 6-membered saturated, partially saturated or aromatic heterocyclic ring; Y represents one or more substituents independently selected from —[O]c—[CH2]d—R1, which may be the same or different at each occurrence; c at each occurrence independently represents a number selected from 0 or 1; d at each occurrence independently represents a number selected from 0 to 6; R1 at each occurrence independently represents H, halo, CF3, CN or Het1; Het1 at each occurrence independently represents a 5- or 6-membered unsaturated heterocyclic ring; V represents a direct link or —O—; Ring A represents an optionally substituted 5- to 7-membered saturated heterocyclic ring, or a phenylene group; Q represents a direct link or

Abstract: A dental apparatus is provided with an ozone irrigation system. Ozonated water is produced in the irrigation system and supplied to the dental apparatus. The dental apparatus can have a handpiece that drives a cannulated instrument, such as a cannulated file. The ozonated water can be supplied to an axial passage formed in the instrument. Radial ports are provided through the instrument such that the ozonated water can spray radially outward into a treatment zone during movement of the instrument. The ozonated water thereby can lubricate and cool the treatment zone while also providing advantageous cleaning of the zone.

Abstract: A manual tong is disclosed which includes a composite belt, a handle assembly, and a jaw assembly, where the composite belt is designed to take the place of the conventional linked chains used currently in manual tongs. The composite belt is held in place by a set of pins associated with the handle and jaw assemblies. Replacement of the linked chains with the composite belts improve tong safety, improve ease of use, lower cost, make adjustment easier and make belt replacement easier reducing down time and increasing tong utility so that one tong can be used for different pipe diameters by simply adjusting a length of the belt or a simple replacement of the belt with a different size belt.

Abstract: A compact package for a garment made from a delicate material includes a container body having a volume of less than 10 in3 (164 cm3), a delicate material garment, a cover member and a cap. The cover member is inserted into the container body atop the garment, followed by the cap. Preferably, a buffer material is arranged between the garment and the cover member within the container body to protect the garment from damage during the packing process. The package is preferably produced by directing the garment and buffer material into a pre-loading tube, followed by shifting of a plunger member to load the container body with the garment, buffer material and the cover member. Subsequently, the cap is snap-fit upon the container body.

Abstract: The present invention relates to devices and methods for controlling molecular reactions involving nucleic acids, such as transcription, by controlling the conformation of nucleic acids bound to a solid support. This is accomplished by applying an electrical bias to a conductor surface which gives rise to a nonspecific attraction or repulsion between the bound nucleic acids and the conductor surface resulting in increased or reduced adsorption of the nucleic acid on the conductor surface. When the nucleic acids are adsorbed onto the conductor surface, their backbone is less accessible to the binding of factors, such as transcription factors, conversely, when the nucleic acids are released from the conductor surface (preferably leaving some interaction with the support) their backbone becomes more accessible to the binding of factors.