Abstract: A veno-arterial extracorporeal membrane oxygenation system includes a dual lumen drainage cannula configured for withdrawing blood from a patient's vasculature in a manner that provides a perfusion of oxygenated blood with reduced carbon dioxide content while unloading the left ventricle, with two points of access to the patient's vasculature. The dual lumen drainage cannula has a first drainage tube and a second drainage tube co-axially aligned with the first drain-age tube. The first and second drainage tubes are fluidly coupled to a connector. A blood pump having a pump inlet is configured for fluidly connecting with the connector, while an oxygenator having an oxygenator inlet is configured for fluidly connecting with a pump outlet. An infusion cannula is configured for fluidly connecting with an oxygenator outlet for infusing oxygenated blood into a patient's bloodstream.

Abstract: A computer-implemented method may include analyzing a resource site based on a plurality of data inputs associated with operation of the resource site. The method may include predicting availability of power for the resource site from a renewable power generation source based on data from the data inputs and determining an operational target for the resource site for a determined future time period, where the operational target may include a power consumption target determined based on the predicted availability of power for the resource site from a renewable power generation source during the determined future time period. The computer-implemented method may further include performing real-time controls of power consumption at the resource site to meet the determined power consumption target for the determined future time period, where the real-time controls may include at least temporarily curtailing or modifying power usage of the resource site during the determined future time period.

Abstract: A computer-implemented method may include analyzing a resource site based on a plurality of data inputs associated with operation of the resource site. The method may include predicting availability of power for the resource site from a renewable power generation source based on data from the data inputs and determining an operational target for the resource site for a determined future time period, where the operational target may include a power consumption target determined based on the predicted availability of power for the resource site from a renewable power generation source during the determined future time period. The computer-implemented method may further include performing real-time controls of power consumption at the resource site to meet the determined power consumption target for the determined future time period, where the real-time controls may include at least temporarily curtailing or modifying power usage of the resource site during the determined future time period.

Abstract: A veno-arterial extracorporeal membrane oxygenation system includes a dual lumen drainage cannula configured for withdrawing blood from a patient's vasculature in a manner that provides a perfusion of oxygenated blood with reduced carbon dioxide content while unloading the left ventricle, with two points of access to the patient's vasculature. The dual lumen drainage cannula has a first drainage tube and a second drainage tube co-axially aligned with the first drainage tube. The first and second drainage tubes are fluidly coupled to a connector. A blood pump having a pump inlet is configured for fluidly connecting with the connector, while an oxygenator having an oxygenator inlet is configured for fluidly connecting with a pump outlet. An infusion cannula is configured for fluidly connecting with an oxygenator outlet for infusing oxygenated blood into a patient's bloodstream.

Abstract: A system for assisting a patient's heart has a pump, an oxygenator, a holder having a pump receiving portion for removably receiving the pump and an oxygenator receiving portion for removably receiving the oxygenator, and a harness configured to surround at least a portion of a patient's torso. The holder is connected to the harness. The system further has a brace connected to at least a portion of the harness. The brace is configured to extend behind a back portion of a user's head and to support tubing connected to at least one of the pump and the oxygenator. A priming tray and wet-to-wet connector connecting the cardiac assist system to the cannula so are also disclosed.

Abstract: Systems and methods are provided for real-time, scalable, systematic, event-based, model-driven operational value optimization for resource sites, such as a data center. A system can receive a plethora of real-time information that impacts the optimization of operations at the resource site. The system can apply some or all of this real-time data to powerful decision-making logic which analyzes various factors gleaned from the real-time information in order to determine a dynamic value optimization for operating the resource site. Methods and systems also provide the ability to adaptively command operation of the resource site (e.g., full curtailment of power and/or compute load, partial curtailment of power and/or compute load, etc.) in a manner that dynamically and in real time optimizes operations. Furthermore, the methods and systems provide a solution that has modularly designed logic and a horizontally designed framework to efficiently support a plethora of applications, even at large-scale.

Abstract: Systems and methods may include receiving real-time inputs associated with events impacting at least one of a plurality of operating parameters of a resource site. The systems and methods may analyze changes in at least one of the plurality of operating parameters in real time based on the real-time inputs and based on a feedback loop, and may dynamically determine an optimization for the resource site, which may include analyzing the operating parameters to determine a dynamic value optimization for operating the resource site in real time. The systems and methods may include performing real-time control of power, compute load, or resource-site infrastructure in accordance with a profitability analysis to achieve and maintain a target operational state. Real-time controls may include continuously adjusting resource site controls to alter power usage and achieve and maintain the determined target operational state in real time to reach the determined dynamic value optimization.

Abstract: Systems and methods may include receiving real-time inputs associated with operational efficiency or profitability of a resource site. The systems and methods may analyze changes in the operational efficiency or profitability in real-time based on the inputs. Implementations may include dynamically determining an operational value optimization for the site, where the operational value optimization may include a profitability analysis based on power cost and revenue generated from compute operations. Moreover, implementations may include determining whether a notice to curtail site operations is received from an external party, and if so, curtailing operations of the resource site accordingly. Also, implementations may include prior to receiving such a notice from a third party, performing real-time controls of power consumption or compute load at the site based on the profitability analysis, where the real-time controls may include at least temporarily curtailing or modifying site power usage.

Abstract: Systems and methods may include receiving real-time inputs associated with events impacting at least one of a plurality of operating parameters of a resource site. The systems and methods may analyze changes in at least one of the plurality of operating parameters in real time based on the real-time inputs and based on a feedback loop, and may dynamically determine an optimization for the resource site, which may include analyzing the operating parameters to determine a dynamic value optimization for operating the resource site in real time. The systems and methods may include performing real-time control of power, compute load, or resource-site infrastructure in accordance with a profitability analysis to achieve and maintain a target operational state. Real-time controls may include continuously adjusting resource site controls to alter power usage and achieve and maintain the determined target operational state in real time to reach the determined dynamic value optimization.

Abstract: Systems and methods are provided for real-time, scalable, systematic, event-based, model-driven operational value optimization for resource sites, such as a data center. A system can receive a plethora of real-time information that impacts the optimization of operations at the resource site. The system can apply some or all of this real-time data to powerful decision-making logic which analyzes various factors gleaned from the real-time information in order to determine a dynamic value optimization for operating the resource site. Methods and systems also provide the ability to adaptively command operation of the resource site (e.g., full curtailment of power and/or compute load, partial curtailment of power and/or compute load, etc.) in a manner that dynamically and in real time optimizes operations. Furthermore, the methods and systems provide a solution that has modularly designed logic and a horizontally designed framework to efficiently support a plethora of applications, even at large-scale.

Abstract: Systems and methods may include receiving real-time inputs associated with operational efficiency or profitability of a resource site. The systems and methods may analyze changes in the operational efficiency or profitability in real-time based on the inputs. Implementations may include dynamically determining an operational value optimization for the site, where the operational value optimization may include a profitability analysis based on power cost and revenue generated from compute operations. Moreover, implementations may include determining whether a notice to curtail site operations is received from an external party, and if so, curtailing operations of the resource site accordingly. Also, implementations may include prior to receiving such a notice from a third party, performing real-time controls of power consumption or compute load at the site based on the profitability analysis, where the real-time controls may include at least temporarily curtailing or modifying site power usage.

Abstract: A dual lumen coaxial cannula assembly includes a first infusion tube having a first elongate body defining a first lumen therethrough and a second drainage tube co-axially aligned with the first infusion tube and having a second elongate body with a second lumen defined by a space between the first infusion tube and second drainage tube. A connector is removably attached to the first infusion tube and the second drainage tube for coupling the dual lumen coaxial cannula to an extracorporeal blood circuit. The first infusion tube and the second drainage tube include a plurality of infusion and drainage apertures, respectively, provided at the distal end and extending through the sidewall of the first infusion tube and the drainage tube, respectively.

Abstract: A dual lumen coaxial cannula, assembly includes a first infusion tube having a first elongate body defining a first lumen therethrough and a second drainage tube co-axially aligned with the first infusion tube and having a second elongate body with a second lumen defined by a space between the first infusion tube and second drainage tube. A connector is removably attached to the first infusion tube and the second drainage tube for coupling the dual lumen coaxial cannula to an extracorporeal blood circuit. The first infusion tube and the second drainage tube include a plurality of infusion and drainage apertures, respectively, provided at the distal end and extending through the sidewall of the first infusion tube and the drainage tube, respectively.

Abstract: A dual lumen coaxial cannula assembly including a first infusion tube having a proximal end, a distal end, and a sidewall extending circumferentially therebetween, as well as a second drainage tube co-axially aligned with the first infusion tube, the second drainage tube having a proximal end, a distal end, and a sidewall extending circumferentially therebetween. The assembly also includes a connector assembly, which has an inlet portion through which a portion of the first infusion tube is configured to extend and an outlet portion through which a portion of the second drainage tube is configured to extend. The connector assembly is configured to enable selective axial displacement of the first infusion tube through the second drainage tube.

Abstract: An extracorporeal blood treatment system including a blood oxygenator having an inlet for receiving deoxygenated blood and an outlet for expelling oxygenated blood. The system also includes a recirculation flow path for recirculating a portion of the oxygenated blood exiting the oxygenator outlet back into the oxygenator inlet. The system may also include a dual-lumen cannula coupled to the oxygenator. The cannula includes a manifold with a first blood pathway communicating with the oxygenator outlet, a second blood pathway communicating with the oxygenator inlet, and a third blood pathway connecting the first blood pathway to the second blood pathway. The manifold passes oxygenated blood received from the oxygenator through the first blood pathway, passes deoxygenated blood received from the patient through the second blood pathway, and passes a portion of the oxygenated blood from the first blood pathway through the third blood pathway to be combined with deoxygenated blood in the second blood pathway.

Abstract: A system for assisting a patient's heart has a pump, an oxygenator, a holder having a pump receiving portion for removably receiving the pump and an oxygenator receiving portion for removably receiving the oxygenator, and a harness configured to surround at least a portion of a patient's torso. The holder is connected to the harness. The system further has a brace connected to at least a portion of the harness. The brace is configured to extend behind a back portion of a user's head and to support tubing connected to at least one of the pump and the oxygenator. A priming tray and wet-to-wet connector connecting the cardiac assist system to the cannula so are also disclosed.

Abstract: A dual lumen coaxial cannula assembly including a first infusion tube having a proximal end, a distal end, and a sidewall extending circumferentially therebetween, as well as a second drainage tube co-axially aligned with the first infusion tube, the second drainage tube having a proximal end, a distal end, and a sidewall extending circumferentially therebetween. The assembly also includes a connector assembly, which has an inlet portion through which a portion of the first infusion tube is configured to extend and an outlet portion through which a portion of the second drainage tube is configured to extend. The connector assembly is configured to enable selective axial displacement of the first infusion tube through the second drainage tube.

Abstract: A system for assisting a patient's heart has a pump, an oxygenator, a holder having a pump receiving portion for removably receiving the pump and an oxygenator receiving portion for removably receiving the oxygenator, and a harness configured to surround at least a portion of a patient's torso. The holder is connected to the harness. The system further has a brace connected to at least a portion of the harness. The brace is configured to extend behind a back portion of a user's head and to support tubing connected to at least one of the pump and the oxygenator. A priming tray and wet-to-wet connector connecting the cardiac assist system to the cannula so are also disclosed.

Abstract: A dual lumen drainage cannula configured for use in a veno-arterial extracorporeal membrane oxygenation (VA ECMO) system includes a first drainage tube having a proximal end, a distal end, and at least one aperture defined in the distal end. The dual lumen drainage cannula further includes a second drainage tube having a proximal end, a distal end, and at least one aperture defined in the distal end. The dual lumen drainage cannula further includes an outlet fitting in fluid communication with the first drainage tube and the second drainage tube. The distal end of the second drainage tube is joined to a portion of the first drainage tube between the proximal and distal ends of the first drainage tube.

Abstract: A dual lumen coaxial cannula assembly includes a first infusion tube having a first elongate body defining a first lumen therethrough and a second drainage tube co-axially aligned with the first infusion tube and having a second elongate body with a second lumen defined by a space between the first infusion tube and second drainage tube. A connector is removably attached to the first infusion tube and the second drainage tube for coupling the dual lumen coaxial cannula to an extracorporeal blood circuit. The first infusion tube and the second drainage tube include a plurality of infusion and drainage apertures, respectively, provided at the distal end and extending through the sidewall of the first infusion tube and the drainage tube, respectively.