Abstract: An accommodating intraocular lens is provided having optical parameters that are altered in-situ, wherein an optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens, responsive to forces applied to a haptic portion to the lens by contraction of the ciliary muscles. Forces applied to the haptic portion may result in fluid displacements from or to the haptic portion from the actuator. Displacement of fluid to the actuator may either increase or reduce the degree of deflection imposed on the lens element by the actuator.

Abstract: An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. Fluid-filled haptics disposed in fluid communication with the space vary the fluid volume in the space responsive to forces applied by the ciliary muscles, thereby causing the periphery of the lens element to deflect relative to the substrate and changing the optical power of the intraocular lens.

Abstract: An accommodating intraocular lens is provided having optical parameters that are altered in-situ, wherein an optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens, responsive to forces applied to a haptic portion to the lens by contraction of the ciliary muscles. Forces applied to the haptic portion may result in fluid displacements from or to the haptic portion from the actuator. Displacement of fluid to the actuator may either increase or reduce the degree of deflection imposed on the lens element by the actuator.

Abstract: An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. Fluid-filled haptics disposed in fluid communication with the space vary the fluid volume in the space responsive to forces applied by the ciliary muscles, thereby causing the periphery of the lens element to deflect relative to the substrate and changing the optical power of the intraocular lens.

Abstract: An accommodating intraocular lens is provided having optical parameters that are altered in-situ, wherein an optic portion of the lens includes a lens piston that alters the shape of a lens element of the lens to alter the optical power of the lens, responsive to forces applied to a haptic portion to the lens by contraction of the ciliary muscles. Forces applied to the haptic portion are transferred hydraulically to cause the lens to become more or less accommodated. The haptic portion is retained in a fixed unaccommodated state during an initial healing period following implantation to facilitate affixation of the haptic portion to the capsule.

Abstract: An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. Fluid-filled haptics disposed in fluid communication with the space vary the fluid volume in the space responsive to forces applied by the ciliary muscles, thereby causing the periphery of the lens element to deflect relative to the substrate and changing the optical power of the intraocular lens.

Abstract: An accommodating intraocular lens is provided having optical parameters that are altered in-situ, wherein an optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens, responsive to forces applied to a haptic portion to the lens by contraction of the ciliary muscles. Forces applied to the haptic portion may result in fluid displacements from or to the haptic portion from the actuator. Displacement of fluid to the actuator may either increase or reduce the degree of deflection imposed on the lens element by the actuator.

Abstract: Apparatus for instilling a medicament into an eye includes a housing having a longitudinal axis and a chamber disposed in the housing for containing a medicament. A nozzle is provided for instilling a dose of medicament into an eye and an actuator meters doses of medicament from the chamber to the nozzle and forces each metered dose through the nozzle upon axial displacement of the actuator along housing longitudinal axis. A spring causes the axial displacement of the actuator upon release of the spring from a compressed state. A collar disposed for rotation about the housing longitudinal axis is provided by compressing the spring by twisting the collar about the housing longitudinal axis and a trigger disposed in a housing is provided for releasing the compressed spring.