Patents by Inventor Patrick Alexander Baeuerle

Patrick Alexander Baeuerle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR AUTOIMMUNITY REGULATION
    Publication number: 20230338421
    Abstract: Provided herein are recombinant nucleic acids encoding T cell receptor (TCR) fusion proteins (TFPs), modified human immune cells expressing the encoded molecules, and methods of use thereof for the treatment of diseases, including autoinmmune diseases.
    Type: Application
    Filed: January 8, 2021
    Publication date: October 26, 2023
    Inventors: Daniel GETTS, Robert HOFMEISTER, Patrick Alexander BAEUERLE, Dario GUTIERREZ, Dana GILMORE
  • COMPOSITIONS AND METHODS FOR GAMMA DELTA TCR REPROGRAMMING USING FUSION PROTEINS
    Publication number: 20230069322
    Abstract: Provided herein are recombinant nucleic acids encoding T cell receptor (TCR) fusion proteins (TFPs), modified ?? T cells expressing the encoded molecules, and methods of use thereof for the treatment of diseases, including cancer.
    Type: Application
    Filed: December 23, 2020
    Publication date: March 2, 2023
    Inventors: Jian DING, Robert HOFMEISTER, Patrick Alexander BAEUERLE, Dario GUTIERREZ, Robert TIGHE, Julio GOMEZ RODRIGUEZ
  • COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING FUSION PROTEINS
    Publication number: 20220362295
    Abstract: Provided herein are recombinant nucleic acids encoding T cell receptor (TCR) fusion proteins (TFPs), modified human immune cells expressing the encoded molecules, and methods of use thereof for the treatment of diseases, including cancer.
    Type: Application
    Filed: April 22, 2020
    Publication date: November 17, 2022
    Inventors: Philippe KIEFFER-KWON, Ella LIBERZON, Robert HOFMEISTER, Patrick Alexander BAEUERLE, Daniel GETTS
  • COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING FUSION PROTEINS
    Publication number: 20210361704
    Abstract: Provided herein are recombinant nucleic acids encoding T cell receptor (TCR) fusion proteins (TFPs) and a TCR constant domain, modified T cells expressing the encoded molecules, and methods of use thereof for the treatment of diseases, including cancer.
    Type: Application
    Filed: March 8, 2019
    Publication date: November 25, 2021
    Inventors: Patrick Alexander BAEUERLE, Robert HOFMEISTER, Daniel GETTS, Philippe KIEFFER-KWON, Julie DONAGHEY
  • COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING TARGET SPECIFIC FUSION PROTEINS
    Publication number: 20210315933
    Abstract: Provided herein are T cell receptor (TCR) fusion proteins (TFPs), T cells engineered to express one or more MUC16 or IL 13R?2 or MSLN TFPs, and methods of use thereof for the treatment of diseases, including cancer.
    Type: Application
    Filed: July 26, 2019
    Publication date: October 14, 2021
    Inventors: Patrick Alexander Baeuerle, Robert Hofmeister, Daniel Getts, Vania Ashminova, Jian Ding
  • COMPOSITIONS AND METHODS FOR TCR REPROGRAMMING USING FUSION PROTEINS
    Publication number: 20210253666
    Abstract: Provided herein are T cell receptor (TCR) fusion proteins (TFPs) having specificity for more than one tumor cell associated antigen, T cells engineered to express one or more TFP, and methods of use thereof for the treatment of diseases, including cancer.
    Type: Application
    Filed: August 30, 2019
    Publication date: August 19, 2021
    Inventors: Patrick Alexander Baeuerle, Robert Hofmeister, Jian Ding, Vania Ashminova, Michael Lofgren