Abstract: Ophthalmic viewing systems for visualizing structures on and in an eye of a medical patient include an ophthalmic microscope, a gonioscopy device configured to work with the ophthalmic microscope to provide an image of an interior of the patient's eye, and a robotic arm configured to hold the gonioscopy device in a position in relation to the ophthalmic microscope and the patient's eye to provide the image of the eye's interior.

Abstract: A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.

Abstract: A medical device includes an elongate hollow shaft having a shaft proximal end, a shaft distal end, and a lumen extending along the elongate hollow shaft. A handle is disposed at the shaft proximal end. A connector assembly having a connector assembly proximal end and a connector assembly distal end, the connector assembly proximal and distal ends being opposite ends of the connector assembly. An expandable frame is detachably disposed at the connector assembly distal end, the expandable frame including a plurality of interconnected members formed of an electrically conductive material, wherein the interconnected members in a first portion of the expandable frame are coated with a dielectric layer, and wherein the interconnected members in a second portion of the expandable frame are uncoated and configured as an electrode region of the expandable frame.

Abstract: A system includes an actuator, one or more items of diagnostic equipment configured to perform ophthalmic measurement, and one or more items of treatment equipment configured to facilitate performance of an ophthalmic treatment with respect to an eye of a patient. A controller is coupled to the actuator and is configured to cause the actuator to transfer the one or more items of diagnostic equipment and the one or more items of treatment equipment into and out of a region in front of an eye of the patient. The ophthalmic treatment may be a LASIK or SMILE treatment using refractive error and/or eye geometry measured using the diagnostic equipment.

Abstract: Earmuffs with a joint are provided to create a biased pressure distribution about a perimeter of the cup. The earmuffs may include a pivot joint. The pressure distribution creates a wedging pressure (e.g., on a top edge) on the cups that hold the earmuffs on the user's head, for example, when the user rotates the headband behind the head. The bias pressure is also used to adjust the seal formed between the pad and the user's head. Adjustments to the moment created by separating the joints from the cup's apex enable a user to selectively adjust the seal according to the user's preference. A cam is added to the headband to change the hoop stress distributed at the joints and further adjust the compressive forces generated to hold the earmuffs against the user's head.

Abstract: A battery pack assembly includes a cell stack having a plurality of battery cells, a thermal barrier adjacent the cell stack, and deflector hoods included within the thermal barrier. Each deflector hood configured to move from a closed position to an open position in response to a flow of vent byproducts against the deflector hood.

Abstract: The present disclosure provides for a modular design and build architecture, comprising: one or more integrated system module (ISMs) that are configured to be shipped and assembled on-site to construct an operational infrastructure for one or more application environments, wherein each of the ISMs comprises two or more different functional components that are integrated onto and/or supported by a common structural floor.

Abstract: A system and method for assisting a surgeon performing an ophthalmic procedure on an eye of a patient, the system including a lubrication assembly. The lubrication assembly may be disposed on a proximal end of a robotic arm, a proximal end of a surgical microscope, or a proximal end of a mobile stand or frame. Dispersal of lubricant from the lubrication assembly may be upon receipt of a direct input from a surgeon, according to a predetermined schedule, or according to an image processing protocol. The lubrication assembly may be moved into position over the eye of the patient manually by the surgeon or through the indirect command of a motion controller which is operable to move the robotic arm or the surgical microscope so as to extend the lubrication assembly into a desired position.

Abstract: Methods, systems, and devices for techniques for data transfer between tiered memory devices are described. A memory system may include a data transfer engine to manage data transfers between different tiers of memory devices within the memory system. The data transfer engine may receive a command which includes a set of source addresses of each of a set of data sets and a set of destination addresses to which the data sets are to be transferred. The data transfer engine may schedule and perform a transfer operation to transfer each of the set of data sets from the respective source address to the respective destination address. The command may further include an indication of an interrupt policy of a set of interrupt policies supported by the data transfer engine. The set of interrupt policies may determine how the data transfer engine may handle interruptions to the data transfer operation.

Abstract: The present invention relates to a method for increasing the activity and/or the yield of a recombinant vitamin K-dependent protein expressed in cell culture. The present invention further relates to uses and compositions of matter.

Abstract: An antenna system comprises a driven antenna element connected to a printed circuit board (PCB), and a plurality of PCB extenders provided by electrical conductors connected to a PCB ground plane for cooperation with the driven antenna element in signal communication. In an eyewear device that incorporates the antenna system, the plurality of PCB extenders are provided by conductive structural elements incorporated in an eyewear frame.

Abstract: One example of an IP KVM device includes a USB port, a display port, a communication port, a network port, and a processor communicatively coupled to the USB port, display port, communication port, and network port. The USB port may be communicatively coupled to a host device to receive first USB signals from the host device. The display port may be communicatively coupled to the host device to receive first display signals from the host device. The communication port may be communicatively coupled to a secondary IP KVM device to receive second USB signals from the host device and second display signals from the host device. The network port may be communicatively coupled to a network. The processor is to aggregate the first and second USB signals and the first and second display signals and output the aggregated USB signals and display signals via the network port.

Abstract: A coupling system for safety headwear is provided. Various embodiments of safety headwear accessories, such as a brim guard, are adjustable to couple to various configurations of safety headwear. The brim guard includes a mechanism to detachably couple accessories, such as a face shield, to the safety headwear.

Abstract: Methods for treating a bacterial infection and for suppressing antibiotic resistance in a patient are described herein. Certain such methods generally involve administering an antibiotic and an adjuvant compound to a patient with a bacterial infection caused by Staphylococcus aureus, wherein the adjuvant compound comprises a fused tricyclic ring system with at least one halogen substituent. Compositions and kits containing such components are also described.

Abstract: A system and process may be used to test water samples to measure ATP and/or estimate a microbial population, for example using an adenosine triphosphate (ATP) based assay. The system includes a device that is use in combination with single-use or disposable cartridges. The cartridge receives the water sample and is pre-loaded with one or more reagents. The device receives the cartridge and contains physical, electronic and/or mechatronic devices that interact with cartridge. One or more actions such as metering, mixing and conveying are performed automatically by elements of the device and/or cartridge. A sensor in the device measures light produced in the cartridge from a reaction with ATP in the water sample. Optionally, the cartridge also contains a pre-loaded amount of ATP, which is used to provide an internal reference or calibration measurement.

Abstract: The present disclosure relates to compounds according to Formula I (I) or a pharmaceutically acceptable salt and/or solvate thereof, as well as compositions including such compounds and uses thereof, where R1 is an unsubstituted C1-C12 alkyl; and R2, R3, and R4 are each independently H or —C(O)—(unsubstituted C1-C12 alkyl). Among other things, the present disclosure evidences that the significant upregulation of CD20 by the inhibition of a-mannosidase enzymes by compounds of the present technology potentiates the activity of anti-CD20 mAbs and importantly sensitize cell lines that are resistant to the action of these antibodies.

Abstract: A pressure regulator includes a fluid transfer chamber defining one or more apertures. A flow control element is disposed within the fluid transfer chamber and is movable with respect to the fluid transfer chamber. An actuator is secured to the flow control element and is operable to move the flow control element with respect to the fluid transfer chamber to control fluid flow through the apertures in the fluid transfer chamber.

Abstract: Apparatuses, methods and storage medium associated with compensating for a sensor deficiency in a heterogeneous sensor array are disclosed herein. In embodiments, an apparatus may include a compute device to aggregate perception data from individual perception pipelines, each of which is associated with respective one of different types of sensors of a heterogeneous sensor set, to identify a characteristic associated with a space to be monitored by the heterogeneous sensor set; detect a sensor deficiency associated with a first sensor of the sensors; and in response to a detection of the sensor deficiency, derive next perception data for more than one of the individual perception pipelines from sensor data originating from at least one second sensor of the sensors. Other embodiments may be disclosed or claimed.

Abstract: A downhole system includes a lower completion having at least one tubular including a first end and a second end terminating at a shoe. The at least one tubular defining a flow path. A packer is arranged at the first end. A fluid loss control valve (FLCV) is arranged between the packer and the shoe. A screen system is arranged between the FLCV and the shoe. The screen system includes a screen and a non-mechanically operated flow control valve that selectively isolates the flow path from formation fluids passing through the screen. A wellbore clean out string is insertable into the lower completion. The wellbore clean out string includes a selectively activated casing cleaner and a setting tool. The selectively activated casing cleaner is spaced from the setting tool.

Abstract: The present disclosure relates to compounds according to Formula I (I) or a pharmaceutically acceptable salt and/or solvate thereof, as well as compositions including such compounds and uses thereof, where R1 is an unsubstituted C1-C12 alkyl; and R2, R3, and R4 are each independently H or —C(O)—(unsubstituted C1-C12 alkyl). Among other things, the present disclosure evidences that the significant upregulation of CD20 by the inhibition of a-mannosidase enzymes by compounds of the present technology potentiates the activity of anti-CD20 mAbs and importantly sensitize cell lines that are resistant to the action of these antibodies.