Abstract: A tripping and filtration object to manage a borehole operation, including a volume of material that is landable upon a seat in a borehole to create a pressure drop such that a function of the borehole subsystem is obtainable. In a second condition, the volume is passable through the seat. In a third condition the volume becomes a filtration media. A method for managing a borehole operation, including conveying an object to a landing seat in a borehole system, functioning the landing seat through application of pressure against the object on the landing seat, passing at least a portion of the object through the landing seat, and changing the at least a portion of the object into a filtration media after passing through the landing seat. A borehole system, including a borehole in a subsurface formation, a string in the borehole, and an object disposed within the string.

Abstract: The present invention relates to compounds which are active against parasitic infections, such as protozoan parasite infections (including flagellate parasite infections, ciliate parasite infections, amoeba parasite infections and apicomplexan parasite infections) and helminth infections. The present invention also relates to compositions comprising the compounds, and methods of treating or preventing parasitic infections, such as protozoan parasite infections (including flagellate parasite infections, ciliate parasite infections, amoeba parasite infections and apicomplexan parasite infections) and helminth infections, using the compounds.

Abstract: Methods for treating a bacterial infection and for suppressing antibiotic resistance in a patient are described herein. Certain such methods generally involve administering an antibiotic and an adjuvant compound to a patient with a bacterial infection caused by Staphylococcus aureus, wherein the adjuvant compound comprises a fused tricyclic ring system with at least one halogen substituent. Compositions and kits containing such components are also described.

Abstract: A system and process may be used to test water samples to measure ATP and/or estimate a microbial population, for example using an adenosine triphosphate (ATP) based assay. The system includes a device that is use in combination with single-use or disposable cartridges. The cartridge receives the water sample and is pre-loaded with one or more reagents. The device receives the cartridge and contains physical, electronic and/or mechatronic devices that interact with cartridge. One or more actions such as metering, mixing and conveying are performed automatically by elements of the device and/or cartridge. A sensor in the device measures light produced in the cartridge from a reaction with ATP in the water sample. Optionally, the cartridge also contains a pre-loaded amount of ATP, which is used to provide an internal reference or calibration measurement.

Abstract: The present disclosure relates to compounds according to Formula I (I) or a pharmaceutically acceptable salt and/or solvate thereof, as well as compositions including such compounds and uses thereof, where R1 is an unsubstituted C1-C12 alkyl; and R2, R3, and R4 are each independently H or —C(O)—(unsubstituted C1-C12 alkyl). Among other things, the present disclosure evidences that the significant upregulation of CD20 by the inhibition of a-mannosidase enzymes by compounds of the present technology potentiates the activity of anti-CD20 mAbs and importantly sensitize cell lines that are resistant to the action of these antibodies.

Abstract: A pressure regulator includes a fluid transfer chamber defining one or more apertures. A flow control element is disposed within the fluid transfer chamber and is movable with respect to the fluid transfer chamber. An actuator is secured to the flow control element and is operable to move the flow control element with respect to the fluid transfer chamber to control fluid flow through the apertures in the fluid transfer chamber.

Abstract: Apparatuses, methods and storage medium associated with compensating for a sensor deficiency in a heterogeneous sensor array are disclosed herein. In embodiments, an apparatus may include a compute device to aggregate perception data from individual perception pipelines, each of which is associated with respective one of different types of sensors of a heterogeneous sensor set, to identify a characteristic associated with a space to be monitored by the heterogeneous sensor set; detect a sensor deficiency associated with a first sensor of the sensors; and in response to a detection of the sensor deficiency, derive next perception data for more than one of the individual perception pipelines from sensor data originating from at least one second sensor of the sensors. Other embodiments may be disclosed or claimed.

Abstract: A downhole system includes a lower completion having at least one tubular including a first end and a second end terminating at a shoe. The at least one tubular defining a flow path. A packer is arranged at the first end. A fluid loss control valve (FLCV) is arranged between the packer and the shoe. A screen system is arranged between the FLCV and the shoe. The screen system includes a screen and a non-mechanically operated flow control valve that selectively isolates the flow path from formation fluids passing through the screen. A wellbore clean out string is insertable into the lower completion. The wellbore clean out string includes a selectively activated casing cleaner and a setting tool. The selectively activated casing cleaner is spaced from the setting tool.

Abstract: The present disclosure relates to compounds according to Formula I (I) or a pharmaceutically acceptable salt and/or solvate thereof, as well as compositions including such compounds and uses thereof, where R1 is an unsubstituted C1-C12 alkyl; and R2, R3, and R4 are each independently H or —C(O)—(unsubstituted C1-C12 alkyl). Among other things, the present disclosure evidences that the significant upregulation of CD20 by the inhibition of a-mannosidase enzymes by compounds of the present technology potentiates the activity of anti-CD20 mAbs and importantly sensitize cell lines that are resistant to the action of these antibodies.

Abstract: A downhole system includes a lower completion having at least one tubular including a first end and a second end terminating at a shoe. The at least one tubular defining a flow path. A packer is arranged at the first end. A fluid loss control valve (FLCV) is arranged between the packer and the shoe. A screen system is arranged between the FLCV and the shoe. The screen system includes a screen and a non-mechanically operated flow control valve that selectively isolates the flow path from formation fluids passing through the screen. A wellbore clean out string is insertable into the lower completion. The wellbore clean out string includes a selectively activated casing cleaner and a setting tool. The selectively activated casing cleaner is spaced from the setting tool.

Abstract: Apparatuses, methods and storage medium associated with compensating for a sensor deficiency in a heterogeneous sensor array are disclosed herein. In embodiments, an apparatus may include a compute device to aggregate perception data from individual perception pipelines, each of which is associated with respective one of different types of sensors of a heterogeneous sensor set, to identify a characteristic associated with a space to be monitored by the heterogeneous sensor set; detect a sensor deficiency associated with a first sensor of the sensors; and in response to a detection of the sensor deficiency, derive next perception data for more than one of the individual perception pipelines from sensor data originating from at least one second sensor of the sensors. Other embodiments may be disclosed or claimed.

Abstract: A downhole system includes a lower completion having at least one tubular including a first end and a second end terminating at a shoe. The at least one tubular defining a flow path. A packer is arranged at the first end. A fluid loss control valve (FLCV) is arranged between the packer and the shoe. A screen system is arranged between the FLCV and the shoe. The screen system includes a screen and a non-mechanically operated flow control valve that selectively isolates the flow path from formation fluids passing through the screen. A wellbore clean out string is insertable into the lower completion. The wellbore clean out string includes a selectively activated casing cleaner and a setting tool. The selectively activated casing cleaner is spaced from the setting tool.

Abstract: A foldable elevator structure having a plurality of members is shown having each current member sequentially attached between a preceding member and a succeeding member. This connection schema continues until the last member is attached to the first member and a completed enclosed structure is formed such that all members have been attached. In this fashion, the foldable structure is foldable between each set of two adjacent members.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed that provide an apparatus to analyze vehicle perspectives, the apparatus comprising a profile generator to generate a first profile of an environment based on a profile template and first data generated by a first vehicle; a data analyzer to: determine a difference between the first profile and a second profile obtained from a first one of one or more nodes in the environment; and in response to a trigger event, update the first profile based on the difference; and a vehicle control system to: in response to the trigger event, update a first perspective of the environment based on one or more of second data from the first one of the one or more nodes or the updated first profile; update a path plan for the first vehicle based on the updated first perspective; and execute the updated path plan.

Abstract: Apparatuses, methods and storage medium associated with compensating for a sensor deficiency in a heterogeneous sensor array are disclosed herein. In embodiments, an apparatus may include a compute device to aggregate perception data from individual perception pipelines, each of which is associated with respective one of different types of sensors of a heterogeneous sensor set, to identify a characteristic associated with a space to be monitored by the heterogeneous sensor set; detect a sensor deficiency associated with a first sensor of the sensors; and in response to a detection of the sensor deficiency, derive next perception data for more than one of the individual perception pipelines from sensor data originating from at least one second sensor of the sensors. Other embodiments may be disclosed or claimed.

Abstract: A foldable elevator structure having a plurality of members is shown having each current member sequentially attached between a preceding member and a succeeding member. This connection schema continues until the last member is attached to the first member and a completed enclosed structure is formed such that all members have been attached. In this fashion, the foldable structure is foldable between each set of two adjacent members.

Abstract: A foldable elevator cabin and a foldable elevator shaft are disclosed. The foldable elevator cabin has a plurality of members attached at a centralized point for centralized folding using arms attached between each member. A ceiling and a base are attached to the top and bottom of the various members. Secondly, a foldable elevator structure having a plurality of members is shown having each member sequentially attached between a preceding member and a succeeding member until all members have been attached. In this fashion, the foldable structure is foldable between each set of two adjacent members.

Abstract: A downhole system includes a lower completion having at least one tubular including a first end and a second end terminating at a shoe. The at least one tubular defining a flow path. A packer is arranged at the first end. A fluid loss control valve (FLCV) is arranged between the packer and the shoe. A screen system is arranged between the FLCV and the shoe. The screen system includes a screen and a non-mechanically operated flow control valve that selectively isolates the flow path from formation fluids passing through the screen. A wellbore clean out string is insertable into the lower completion. The wellbore clean out string includes a selectively activated casing cleaner and a setting tool. The selectively activated casing cleaner is spaced from the setting tool.

Abstract: A decision support system and method can be used to control a water treatment or distribution system. The decision support system collects data from multiple water system operators and analyses the data for a selected water system according to one or more rules or algorithms. The system returns data, optionally including alerts or predictions, to the system operator. Optionally, the decision support system uses machine learning applied to (i) historical data from a selected water system and/or (ii) data from other water systems to modify the rules or algorithms used to analyze current data from a selected water system. In some embodiments, the data collected includes microbial population data such as ATP data, optionally including derivatives of microbial population data; microbial speciation information; or, metagenomic data.

Abstract: The present disclosure is directed toward systems and methods for providing message element in electronic communication threads. For example, systems and methods described herein identify message elements in electronic communication threads and add interactions between the message elements to the electronic communication thread.