Patents by Inventor Patrick Anglard

Patrick Anglard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for use in modulating expression of matrix metalloproteinase genes
    Patent number: 6184256
    Abstract: The present invention relates to methods for identifying and selecting compositions useful in differentially modulating the expression of two or more mammalian genes, particularly matrix metalloproteinase (MMP) genes such as those encoding interstitial collagenase (and other genes comprising an AP1-binding site) and stromelysin-3 (and other genes comprising a retinoic acid response element (RARE)). In addition, the invention relates to methods of treating a mammal (such as a human) suffering from or predisposed to a physical disorder, using pharmaceutical compositions comprising the compositions identified or selected by the above-described methods. The methods of the present invention are useful in treating a variety of physical disorders in mammals including cancers (particularly carcinomas), inflammatory disorders, fibrotic disorders, ocular disorders and osteoporosis.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: February 6, 2001
    Assignees: Institut National de la Santé de la Recherche Médicale, Centre National de la Recherche Scientifique, Université Louis Pasteur, Bristol-Myers Squibb Company
    Inventors: Paul Basset, Patrick Anglard, Eric Guérin