Patents by Inventor Patrick Arnold
Patrick Arnold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230231167Abstract: An apparatus for splitting the power of fuel cell systems in a vehicle comprises: a first fuel cell system and at least one further fuel cell system, which are configured to convert hydrogen and oxygen into water in order to generate electrical energy therefrom, and a controller unit, which is configured to actuate the first fuel cell system and the further fuel cell system with an electrical signal. The apparatus is configured to actuate the first fuel cell system and the further fuel cell system with the electrical signal in time offset fashion.Type: ApplicationFiled: July 15, 2021Publication date: July 20, 2023Inventors: Markus RUF, Martin ARENDT, Hannah STAUB, Patrick ARNOLD
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Publication number: 20220124251Abstract: A blind spot monitoring device includes a housing, a chipset, a power source, a plurality of focused-beam illuminating units, a camera unit, and at least one sensor. The chipset is internally mounted within the housing, and the power source is integrated onto the housing. The plurality of focused-beam illuminating units is mounted onto the housing and functions a spotlight for the camera unit that is mounted onto the housing. The sensor is mounted onto the housing and continuously monitor the surveillances area. The chipset, the plurality of focused-beam illuminating units, the camera unit, and the sensor are electrically connected to the power source so that the blind spot monitoring device can be powered from the power source. The plurality of focused-beam illuminating units, the camera unit, and the sensor are electronically connected to the chipset so that the blind spot monitoring device can be programed and operated.Type: ApplicationFiled: December 29, 2021Publication date: April 21, 2022Inventor: Patrick Arnold
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Publication number: 20220005333Abstract: Disclosed is a smart security monitoring device and system.Type: ApplicationFiled: July 2, 2021Publication date: January 6, 2022Inventor: Patrick Arnold
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Publication number: 20210161850Abstract: The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and A?-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two.Type: ApplicationFiled: November 23, 2020Publication date: June 3, 2021Inventors: Dominic Paul D'Agostino, Jay B. Dean, Raffaele Pilla, Patrick Arnold
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Patent number: 10842767Abstract: The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and A?-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two.Type: GrantFiled: November 12, 2013Date of Patent: November 24, 2020Assignee: University of South FloridaInventors: Dominic Paul D'Agostino, Jay B. Dean, Raffaele Pilla, Patrick Arnold
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Patent number: 10792259Abstract: ?-hydroxy butyric acid in combination with ?-hydroxybutyrate salts are useful to induce ketosis, achieving blood ketone levels of (0.5-6.0 mmol/L), with or without dietary restriction, and without inducing harmfully high mineral loads in the blood. The combination of ?-hydroxy butyric acid and salt results in substantial improvements in metabolic bookmakers related to insulin resistance, diabetes, weight loss, and physical performance & endurance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. These acid/salt mixtures are also useful for suppressing appetite, preventing epileptic seizures, and treating cancer.Type: GrantFiled: March 12, 2020Date of Patent: October 6, 2020Assignee: Savlnd, Inc.Inventor: Patrick Arnold
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Publication number: 20200268701Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: ApplicationFiled: May 11, 2020Publication date: August 27, 2020Inventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Publication number: 20200206168Abstract: ?-hydroxy butyric acid in combination with ?-hydroxybutyrate salts are useful to induce keto sis, achieving blood ketone levels of (0.5-6.0 mmol/L), with or without dietary restriction, and without inducing harmfully high mineral loads in the blood. The combination of ?-hydroxy butyric acid and salt results in substantial improvements in metabolic bookmakers related to insulin resistance, diabetes, weight loss, and physical performance & endurance in a short period of time. Further, use of these supplements to achieve keto sis yields a significant elevation of blood ketones and reduction of blood glucose levels. These acid/salt mixtures are also useful for suppressing appetite, preventing epileptic seizures, and treating cancer.Type: ApplicationFiled: March 12, 2020Publication date: July 2, 2020Inventor: Patrick Arnold
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Patent number: 10646462Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: GrantFiled: June 1, 2017Date of Patent: May 12, 2020Assignee: University of South FloridaInventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Patent number: 10588877Abstract: ?-hydroxybutyric acid in combination with ?-hydroxybutyrate salts are useful to induce ketosis, achieving blood ketone levels of (0.5-6.0 mmol/L), with or without dietary restriction, and without inducing harmfully high mineral loads in the blood. The combination of ?-hydroxybutyric acid and salt results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance & endurance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. These acid/salt mixtures are also useful for suppressing appetite, preventing epileptic seizures, and treating cancer.Type: GrantFiled: March 27, 2017Date of Patent: March 17, 2020Assignee: SavInd, Inc.Inventor: Patrick Arnold
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Publication number: 20180021274Abstract: ?-hydroxybutyric acid in combination with ?-hydroxybutyrate salts are useful to induce ketosis, achieving blood ketone levels of (0.5-6.0 mmol/L), with or without dietary restriction, and without inducing harmfully high mineral loads in the blood. The combination of ?-hydroxybutyric acid and salt results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance & endurance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. These acid/salt mixtures are also useful for suppressing appetite, preventing epileptic seizures, and treating cancer.Type: ApplicationFiled: March 27, 2017Publication date: January 25, 2018Inventor: Patrick Arnold
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Patent number: 9801903Abstract: A method of treating cancer using ketogenic diet, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.Type: GrantFiled: April 28, 2015Date of Patent: October 31, 2017Assignee: University of South FloridaInventors: Dominic Paul D'Agostino, Angela Marie Poff, Patrick Arnold
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Publication number: 20170266148Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: ApplicationFiled: June 1, 2017Publication date: September 21, 2017Applicant: University of South FloridaInventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Patent number: 9675577Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: GrantFiled: September 21, 2015Date of Patent: June 13, 2017Assignee: University of South FloridaInventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Publication number: 20160067207Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: ApplicationFiled: September 21, 2015Publication date: March 10, 2016Applicant: UNIVERSITY OF SOUTH FLORIDAInventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Patent number: 9138420Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: GrantFiled: August 8, 2014Date of Patent: September 22, 2015Assignee: University of South FloridaInventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Publication number: 20150231172Abstract: A method of treating cancer using ketogenic diet, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.Type: ApplicationFiled: April 28, 2015Publication date: August 20, 2015Applicant: UNIVERSITY OF SOUTH FLORIDAInventors: Dominic Paul D'Agostino, Angela Marie Poff, Patrick Arnold
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Publication number: 20140350105Abstract: Beta-hydroxybutyrate mineral salts in combination with medium chain fatty acids or an ester thereof such as medium chain triglycerides were used to induce ketosis, achieving blood ketone levels of (2-7 mmol/L), with or without dietary restriction. The combination results in substantial improvements in metabolic biomarkers related to insulin resistance, diabetes, weight loss, and physical performance in a short period of time. Further, use of these supplements to achieve ketosis yields a significant elevation of blood ketones and reduction of blood glucose levels. Use of these substances does not adversely affect lipid profiles. By initiating rapid ketosis and accelerating the rate of ketoadaptation, this invention is useful for the avoidance of glucose withdrawal symptoms commonly experienced by individuals initiating a ketogenic diet, and minimizes the loss of lean body mass during dietary restriction.Type: ApplicationFiled: August 8, 2014Publication date: November 27, 2014Applicant: University of South FloridaInventors: Dominic Paul D'Agostino, Patrick Arnold, Shannon Kesl
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Publication number: 20140073693Abstract: The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease and malignant brain cancer, which are associated with metabolic dysregulation. The administration of ketone esters resulted therapeutic ketosis and neuroprotection against seizures resulting from CNS oxygen toxicity. Supplemental ketones were also found to reduce superoxide production in cultured cortex neurons exposed to hyperbaric oxygen and A?-42, and to decrease proliferation and viability in U87 glioma cells. These observations support the therapeutic effect of ketones for seizure disorders, Alzheimer's disease and malignant brain cancer. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two.Type: ApplicationFiled: November 12, 2013Publication date: March 13, 2014Applicants: SAVIND, INC., UNIVERSITY OF SOUTH FLORIDAInventors: Dominic Paul D'Agostino, Jay B. Dean, Raffaele Pilla, Patrick Arnold
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Publication number: 20140072654Abstract: The present invention demonstrates the therapeutic use of ketone esters for seizure disorders, Alzheimer's disease malignant brain cancer, and other cancers, which are associated with metabolic dysregulation. The administration of a ketogenic diet, such as ketone esters, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment resulted in therapeutic ketosis. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The ketone esters may be derived from acetoacetate and can include R,S-1,3-butanediol acetoacetate monoester, R,S-1,3-butanediol acetoacetate diester, or a combination of the two. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.Type: ApplicationFiled: November 12, 2013Publication date: March 13, 2014Applicants: SAVIND, INC., UNIVERSITY OF SOUTH FLORIDAInventors: Dominic Paul D'Agostino, Patrick Arnold, Angela Marie Poff