Patents by Inventor Patrick Augustijns

Patrick Augustijns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for release of biologically active species from mesoporous oxide systems
    Patent number: 8258137
    Abstract: A process for the release of a biologically active species comprising the steps of: providing a mesoporous oxide-based material having structural order and at least one level of porosity; fixing or immobilizing said biologically active species in said ordered mesoporous oxide; and providing said ordered mesoporous oxide with said fixed or immobilized biologically active species in vivo thereby realizing intraluminally induced substantially pH-independent supersaturation of said biologically active species resulting in enhanced transepithelial transport; wherein said biologically active species is a poorly soluble therapeutic drug classified as belonging to Class II or Class IV of the Biopharmaceutical Classification System and said ordered mesoporous oxide has a pore size in the range of 4 to 14 nm.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: September 4, 2012
    Assignee: Katholieke Universiteit Leuven
    Inventors: Patrick Augustijns, Johan Adriaan Martens, Randy Mellaerts, Guy Van Den Mooter
  • PROCESS FOR RELEASE OF BIOLOGICALLY ACTIVE SPECIES
    Publication number: 20110060020
    Abstract: A process for the release of a biologically active species comprising the steps of: providing a mesoporous oxide-based material having structural order and at least one level of porosity; fixing or immobilizing said biologically active species in said ordered mesoporous oxide; and providing said ordered mesoporous oxide with said fixed or immobilized biologically active species in vivo thereby realizing intraluminally induced substantially pH-independent supersaturation of said biologically active species resulting in enhanced transepithelial transport; wherein said biologically active species is a poorly soluble therapeutic drug classified as belonging to Class II or Class IV of the Biopharmaceutical Classification System and said ordered mesoporous oxide has a pore size in the range of 4 to 14 nm.
    Type: Application
    Filed: January 28, 2009
    Publication date: March 10, 2011
    Applicant: Katholieke Universiteit Leuven K.U. Leuven R&D
    Inventors: Patrick AUGUSTIJNS, Johan Adriaan Martens, Randy Mellaerts, Guy Van Den Mooter
  • PROCESS FOR RELEASE OF BIOLOGICALLY ACTIVE SPECIES
    Publication number: 20090318519
    Abstract: A process for the release of a biologically active species comprising the steps of: providing a mesoporous oxide-based material having structural order and at least one level of porosity; fixing or immobilizing said biologically active species in said ordered mesoporous oxide; and providing said ordered mesoporous oxide with said fixed or immobilized biologically active species in vivo thereby realizing intraluminally induced substantially pH-independent supersaturation of said biologically active species resulting in enhanced transepithelial transport; wherein said biologically active species is a poorly soluble therapeutic drug classified as belonging to Class II or Class IV of the Biopharmaceutical Classification System and said ordered mesoporous oxide has a pore size in the range of 4 to 14 nm.
    Type: Application
    Filed: January 28, 2009
    Publication date: December 24, 2009
    Applicant: Katholieke Universiteit Leuven
    Inventors: Patrick AUGUSTIJNS, Johan Adriaan MARTENS, Randy MELLAERTS, Guy VAN DEN MOOTER
  • PROCESS FOR RELEASE OF BIOLOGICALLY ACTIVE SPECIES
    Publication number: 20090192205
    Abstract: A process for the release of a biologically active species comprising the steps of: providing a mesoporous oxide-based material having structural order and at least one level of porosity; fixing or immobilizing said biologically active species in said ordered mesoporous oxide; and providing said ordered mesoporous oxide with said fixed or immobilized biologically active species in vivo thereby realizing intraluminally induced substantially pH-independent supersaturation of said biologically active species resulting in enhanced transepithelial transport; wherein said biologically active species is a poorly soluble therapeutic drug classified as belonging to Class II or Class IV of the Biopharmaceutical Classification System and said ordered mesoporous oxide has a pore size in the range of 4 to 14 nm.
    Type: Application
    Filed: January 28, 2009
    Publication date: July 30, 2009
    Applicant: Katholieke Universiteit Leuven K.U. Leuven R&D
    Inventors: Patrick AUGUSTIJNS, Johan Adriaan Martens, Randy Mellaerts, Guy Van Den Mooter