Abstract: Implementations described and claimed herein provide systems and methods for patient device management. In one implementation, interrogation data is received from a cardiac implantable electronic device corresponding to an interrogation for a patient. The interrogation data includes device data for the cardiac implantable electronic device and patient specific data for the patient. The interrogation data is normalized into manufacturer independent interrogation data. The manufacturer independent interrogation data is associated with a permitted user. A processing status is assigned to the interrogation using the manufacturer independent interrogation data. The interrogation is aggregated into a category based on the processing status, and the category is associated with an action by the permitted user.

Abstract: Disclosed are methods of using inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1), e.g., in the treatment of subjects in need thereof.

Abstract: Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Abstract: Disclosed are compounds and pharmaceutically acceptable salts thereof that may be used in the treatment of subjects in need thereof. The compounds disclosed herein may be inhibitors of tyrosine and threonine-specific cdc2-inhibitory kinase (Myt1). Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.

Abstract: Implementations described and claimed herein provide systems and methods for patient device management. In one implementation, interrogation data is received from a cardiac implantable electronic device corresponding to an interrogation for a patient. The interrogation data includes device data for the cardiac implantable electronic device and patient specific data for the patient. The interrogation data is normalized into manufacturer independent interrogation data. The manufacturer independent interrogation data is associated with a permitted user. A processing status is assigned to the interrogation using the manufacturer independent interrogation data. The interrogation is aggregated into a category based on the processing status, and the category is associated with an action by the permitted user.

Abstract: Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.

Abstract: Implementations described and claimed herein provide systems and methods for patient device management. In one implementation, interrogation data is received from a cardiac implantable electronic device corresponding to an interrogation for a patient. The interrogation data includes device data for the cardiac implantable electronic device and patient specific data for the patient. The interrogation data is normalized into manufacturer independent interrogation data. The manufacturer independent interrogation data is associated with a permitted user. A processing status is assigned to the interrogation using the manufacturer independent interrogation data. The interrogation is aggregated into a category based on the processing status, and the category is associated with an action by the permitted user.

Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.

Abstract: Reducing false negatives and finding new classes in object detectors is disclosed. Also disclosed is a method that includes grouping together a plurality of cropped image portions from region proposals based on image properties. The method also includes receiving first user input that either establishes that the grouped together, cropped image portions relate to uninteresting objects or establishes that the grouped together, cropped image portions relate to an object class of interesting objects. The method also includes obtaining, only when the grouped together, cropped image portions relate to the object class of interesting objects, second user input that includes an object label corresponding to the object class of interesting objects.

Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.

Abstract: Implementations described and claimed herein provide systems and methods for patient device management. In one implementation, interrogation data is received from a cardiac implantable electronic device corresponding to an interrogation for a patient. The interrogation data includes device data for the cardiac implantable electronic device and patient specific data for the patient. The interrogation data is normalized into manufacturer independent interrogation data. The manufacturer independent interrogation data is associated with a permitted user. A processing status is assigned to the interrogation using the manufacturer independent interrogation data. The interrogation is aggregated into a category based on the processing status, and the category is associated with an action by the permitted user.

Abstract: A physical security system is described comprising a simplified method for selection of a compute node from a cluster of compute nodes with which to assign a role or acquire a service. The method determines a scalar priority value for compute nodes in the cluster, and allows selection of a compute node by simply choosing the highest priority scalar value. Scalar priority values may be determined by one or more of: a compute node license type, capacity limits, a hardware capability, a software capability, and a current node load.

Abstract: Example medical device data platforms are disclosed herein. In an example, the platform may include at least one integration device to access information originating from a plurality of implantable medical devices manufactured by a plurality of manufacturers and implanted in a plurality of patients. The system may also include an information processor to process the accessed information to generate at least one of patient-oriented information and provider-oriented information. The system may also include at least one communication device providing at least one of a patient portal and a provider portal to provide the patient-oriented information and the provider-oriented information, respectively.

Abstract: A system including a sensor, a mobile device, and a computer system is disclosed. The sensor is configured to detect physiologic data from the body of the patient. The mobile device includes a patient data input device. The computer system, communicatively coupled to the mobile device, includes a patient record indicating: patient data comprising a plurality of patient activities, and detected physiological data received from the sensor via the mobile device. The computer system is configured to identify an unhealthy physiological data value from the detected physiological data of the patient record, correlate the unhealthy physiological data value to a patient activity of the patient data, select a therapeutic recommendation to address the unhealthy physiological data value, and transmit the selected therapeutic recommendation to the patient, via the mobile device, at a future time associated with the patient activity correlated to the unhealthy physiological data value.