Patents by Inventor Patrick Brest

Patrick Brest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing and treating a pathology associated with a synonymous mutation occuring within a gene of interest
    Patent number: 8771937
    Abstract: The present invention relates to a method for diagnosing and/or prognosing a pathology (such as inflammatory disease, especially Crohn disease) associated with a synonymous mutation occurring within a gene of interest (such as IRGM, NOD2 or BSN) in a subject and to a method for treating such pathology in a subject.
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: July 8, 2014
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), The Nice Sophia Antipolis University
    Inventors: Patrick Brest, Paul Hofman, Baharia Mograbi
  • METHODS FOR DIAGNOSING AND TREATING A PATHOLOGY ASSOCIATED WITH A SYNONYMOUS MUTATION OCCURING WITHIN A GENE OF INTEREST
    Publication number: 20120289582
    Abstract: The present invention relates to a method for diagnosing and/or prognosing a pathology (such as inflammatory dis-ease, especially Crohn disease) associated with a synonymous mutation occurring within a gene of interest (such as IRGM, NOD2 or BSN) in a subject and to a method for treating such pathology in a subject.
    Type: Application
    Filed: October 13, 2010
    Publication date: November 15, 2012
    Inventors: Patrick Brest, Paul Hofman, Baharia Mograbi
  • Therapeutic Combination
    Publication number: 20090036368
    Abstract: A combination of component (i) which is HAMLET or a biologically active modification thereof, or a biologically active fragment of either of these, and component (ii) which is a histone deacetylase (HDAC) inhibitor. This combination shows synergistic effects in the treatment of for example proliferative diseases such as those which produce tumours.
    Type: Application
    Filed: September 14, 2006
    Publication date: February 5, 2009
    Applicant: HAMLET PHARMA AB
    Inventors: Patrick Brest, Catharina Svanborg