Abstract: In some embodiments, an image sensor structure receives light from a color filter array that includes multiple regions. A high resolution region includes a first bayer pattern of color filters that filter light for individual sensors of a sensor array while a lower resolution region includes second bayer pattern of color filters that filter light for groups of sensors of the sensor array. Images may be read from the image sensor in multiple resolutions, with images read in a highest resolution mode preserving maximum detail while images read in lower resolution modes may requires less hardware and computational resources and may exhibit better noise performance, in some embodiments. Various regions of the image sensor structure may correspond to different modes of operation or differing resolving capabilities of a corresponding lens assembly for the image sensor structure.