Patents by Inventor Patrick C. Seed

Patrick C. Seed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BACTERIAL ENZYMATIC CONVERSION OF ANTHRACYCLINE CHEMOTHERAPEUTICS TO REDUCE TOXICITY AND PROMOTE DIVERSITY AMONG THE INTESTINAL MICROBIOTA
    Publication number: 20220184147
    Abstract: Abstract: Disclosed are methods and compositions for treating a subject where the subject is undergoing or is about to undergo treatment with an anthracycline chemotherapeutic. In the disclosed methods, a subject may be administered an anthracycline chemotherapeutic and the subject further may be administered a detoxifying therapeutic agent that detoxifies the anthracycline chemotherapeutic, such as one or more enzymes that catalyze metabolism of the anthracycline chemotherapeutic or one or more probiotic organisms that express the one or more enzymes that catalyze metabolism of the anthracycline chemotherapeutic.
    Type: Application
    Filed: March 4, 2020
    Publication date: June 16, 2022
    Inventors: Ryan A. Blaustein, Patrick C. Seed, Erica M. Hartmann
  • Antimicrobial prochelators to target drug-resistant bacteria and methods of making and using the same
    Patent number: 10533018
    Abstract: The present disclosure provides antibacterial prodrugs and methods of making and using the same.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: January 14, 2020
    Assignee: Duke University
    Inventors: Katherine J. Franz, David M. Besse, Patrick C. Seed
  • ANTIMICROBIAL PROCHELATORS TO TARGET DRUG-RESISTANT BACTERIA AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20180194778
    Abstract: The present disclosure provides antibacterial prodrugs and methods of making and using the same.
    Type: Application
    Filed: June 28, 2016
    Publication date: July 12, 2018
    Inventors: Katherine J. Franz, David M. Besse, Patrick C. Seed
  • Ethoxyphenyl thienyl compounds and methods for the treatment of bacterial infections
    Patent number: 9688653
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: June 27, 2017
    Assignees: Duke University, University of Kansas, Southern Research Institute
    Inventors: Patrick C. Seed, Carlos C. Goller, Steven Rogers, Brooks Maki, Frank Schoenen, James Noah, E. Lucile White
  • Methods for the treatment of bacterial infections
    Patent number: 9593095
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Grant
    Filed: June 16, 2014
    Date of Patent: March 14, 2017
    Assignees: Duke University, University of Kansas, Southern Research Institute
    Inventors: Patrick C. Seed, Carlos C. Goller, Steven Rogers, Brooks Maki, Frank Schoenen, James Noah, E. Lucile White
  • ETHOXYPHENYL THIENYL COMPOUNDS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20150031658
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Application
    Filed: October 15, 2014
    Publication date: January 29, 2015
    Inventors: Patrick C. Seed, Carlos C. Goller, Apurba Dutta, Brooks Maki, Frank Schoenen, James Noah, Lucile White
  • METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS
    Publication number: 20140371194
    Abstract: This invention relates generally to the discovery of a method of inhibiting, preventing or treating bacterial infections. The invention also relates to a method of inhibiting bacterial capsule biogenesis.
    Type: Application
    Filed: June 16, 2014
    Publication date: December 18, 2014
    Inventors: Patrick C. Seed, Carlos C. Goller, Apurba Dutta, Brooks Maki, Frank Schoenen, James Noah, Lucile White