Abstract: Provided herein are devices and methods for isolation and detection of an analyte from a sample. In some embodiments, provided herein are devices and methods of use thereof for vertical flow-based isolation and detection of analytes in a liquid sample, such as a urine sample.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-readable storage media, for speech recognition using attention-based sequence-to-sequence models. In some implementations, audio data indicating acoustic characteristics of an utterance is received. A sequence of feature vectors indicative of the acoustic characteristics of the utterance is generated. The sequence of feature vectors is processed using a speech recognition model that has been trained using a loss function that uses a set of speech recognition hypothesis samples, the speech recognition model including an encoder, an attention module, and a decoder. The encoder and decoder each include one or more recurrent neural network layers. A sequence of output vectors representing distributions over a predetermined set of linguistic units is obtained. A transcription for the utterance is obtained based on the sequence of output vectors. Data indicating the transcription of the utterance is provided.

Abstract: The invention provides methods and systems of determining biopolymer profiles and correlations between structural units (residues) of a biopolymer based on sampling of the conformational space available to the molecule. The correlations between these structural units can further be used to find networks within a biopolymer such as the coupled residue networks in a protein. The invention also provides for designing and engineering biopolymers including polypeptides, nucleic acids and carbohydrates using the information derived from the conformation clustering and subsequent methods described herein.

Abstract: The purpose of the “Dissolvable on-command Implant” is to act as a pressure equalizer tube in the eardrum, which has the unique characteristic that the tube can be dissolved with a specially formulated drop solution on-command. This tube can have various shapes and sizes, although the tube is usually a cylindrical tube with a hollow center, which maintains a ventilatory port for the middle ear space. With this design, the ear tube promotes drainage of middle ear fluid, lets air enter the middle ear, and allows for instillation of antibiotic drops.

Abstract: A system and a method are disclosed for efficiently executing database queries using a computing device that includes a central processing unit (CPU) and a processing unit based on single instruction multiple thread (SIMT) architecture, for example, a GPU. A query engine determines a target processing unit to execute a database query based on factors including the type and amount of data processed by the query, the complexity of the query, and the current load on the processing units. An intermediate executable representation generator generates an intermediate executable representation for executing a query on a database virtual machine. If the query engine determines that the database query should be executed on an SIMT based processing unit, a native code generator generates native code from the intermediate executable representation. The native code is optimized for execution using a particular processing unit.

Abstract: The invention provides methods and systems of determining biopolymer profiles and correlations between structural units (residues) of a biopolymer based on sampling of the conformational space available to the molecule. The correlations between these structural units can further be used to find networks within a biopolymer such as the coupled residue networks in a protein. The invention also provides for designing and engineering biopolymers including polypeptides, nucleic acids and carbohydrates using the information derived from the conformation clustering and subsequent methods described herein.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: The invention provides methods and systems of determining biopolymer profiles and correlations between structural units (residues) of a biopolymer based on sampling of the conformational space available to the molecule. The correlations between these structural units can further be used to find networks within a biopolymer such as the coupled residue networks in a protein. The invention also provides for designing and engineering biopolymers including polypeptides, nucleic acids and carbohydrates using the information derived from the conformation clustering and subsequent methods described herein.

Abstract: A system and a method are disclosed for efficiently executing database queries using a computing device that includes a central processing unit (CPU) and a processing unit based on single instruction multiple thread (SIMT) architecture, for example, a GPU. A query engine determines a target processing unit to execute a database query based on factors including the type and amount of data processed by the query, the complexity of the query, and the current load on the processing units. An intermediate executable representation generator generates an intermediate executable representation for executing a query on a database virtual machine. If the query engine determines that the database query should be executed on an SIMT based processing unit, a native code generator generates native code from the intermediate executable representation. The native code is optimized for execution using a particular processing unit.

Abstract: A system and a method are disclosed for efficiently executing database queries using a computing device that includes a central processing unit (CPU) and a processing unit based on single instruction multiple thread (SIMT) architecture, for example, a GPU. A query engine determines a target processing unit to execute a database query based on factors including the type and amount of data processed by the query, the complexity of the query, and the current load on the processing units. An intermediate executable representation generator generates an intermediate executable representation for executing a query on a database virtual machine. If the query engine determines that the database query should be executed on an SIMT based processing unit, a native code generator generates native code from the intermediate executable representation. The native code is optimized for execution using a particular processing unit.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: The purpose of the “Dissolvable on-command Implant” is to act as a pressure equalizer tube in the eardrum, which has the unique characteristic that the tube can be dissolved with a specially formulated drop solution on-command. This tube can have various shapes and sizes, although the tube is usually a cylindrical tube with a hollow center, which maintains a ventilatory port for the middle ear space. With this design, the ear tube promotes drainage of middle ear fluid, lets air enter the middle ear, and allows for instillation of antibiotic drops.

Abstract: A system and a method are disclosed for efficiently executing database queries using a computing device that includes a central processing unit (CPU) and a processing unit based on single instruction multiple thread (SIMT) architecture, for example, a GPU. A query engine determines a target processing unit to execute a database query based on factors including the type and amount of data processed by the query, the complexity of the query, and the current load on the processing units. An intermediate executable representation generator generates an intermediate executable representation for executing a query on a database virtual machine. If the query engine determines that the database query should be executed on an SIMT based processing unit, a native code generator generates native code from the intermediate executable representation. The native code is optimized for execution using a particular processing unit.

Abstract: A system and a method are disclosed for efficiently executing database queries using a computing device that includes a central processing unit (CPU) and a processing unit based on single instruction multiple thread (SIMT) architecture, for example, a GPU. A query engine determines a target processing unit to execute a database query based on factors including the type and amount of data processed by the query, the complexity of the query, and the current load on the processing units. An intermediate executable representation generator generates an intermediate executable representation for executing a query on a database virtual machine. If the query engine determines that the database query should be executed on an SIMT based processing unit, a native code generator generates native code from the intermediate executable representation. The native code is optimized for execution using a particular processing unit.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: A system and a method are disclosed for effectively displaying database records on a device having a display area that is small compared to the underlying data being represented. A simulated catalogue is displayed with cards associated with database records. Detailed information is presented for a record on a card obscuring information related to other records. A user is allowed to swipe on the catalogue causing simulated movement of the cards thereby displaying information associated with a database record previously obscured. The catalogue is moved with an initial velocity determined by the speed of swiping and decelerated based on a drag factor until it comes to a stop and displays information for the record reached. The ability to determine the final record displayed when the catalogue stops allows pre-fetching of the data associated with the record.

Abstract: The invention provides methods and systems of determining biopolymer profiles and correlations between structural units (residues) of a biopolymer based on sampling of the conformational space available to the molecule. The correlations between these structural units can further be used to find networks within a biopolymer such as the coupled residue networks in a protein. The invention also provides for designing and engineering biopolymers including polypeptides, nucleic acids and carbohydrates using the information derived from the conformation clustering and subsequent methods described herein.