Abstract: Systems and methods presented herein include sidewall coring tool assemblies used to return core plugs of rock from a sidewall of a wellbore as part of a data collection exercise for exploration and production of hydrocarbons. A coring bit and a coring shaft of the present disclosure allow space for cuttings to move away from the bit face when drilling into a formation. In addition, certain embodiments include a plurality of inlets disposed circumferentially on an external surface at a first axial end of the coring shaft, a plurality of internal grooves disposed on an internal surface of the coring shaft, and/or a plurality of fins disposed on the external surface to direct flow of drilling and debris away from the coring bit. In addition to providing more space for cuttings to move away from the coring bit, the torque needed to drive the bit is lessened as the surface area of the bit contacting or engaging the formation is reduced.

Abstract: h The present disclosure provides compositions, methods, and systems related to template-mediated genome editing and modification. In particular, the present disclosure provides novel genome modification technology involving site-specific chemical modification of a nucleotide to introduce a replication-blocking lesion. The compositions, methods, and systems described herein facilitate efficient site-specific genome modification of a DNA target, while minimizing the unintended edits and cellular toxicity associated with current genome editing approaches.

Abstract: The invention features a headset, and systems including the headset, equipped with electrical sensors. The headset is suitable for use by a child and suitable for use in a gaming system, e.g., to train attention.

Abstract: h The present disclosure provides compositions, methods, and systems related to template-mediated genome editing and modification. In particular, the present disclosure provides novel genome modification technology involving site-specific chemical modification of a nucleotide to introduce a replication-blocking lesion. The compositions, methods, and systems described herein facilitate efficient site-specific genome modification of a DNA target, while minimizing the unintended edits and cellular toxicity associated with current genome editing approaches.

Abstract: Systems and methods electronically obtain data regarding a plurality of sources and corresponding amounts of resources received from the sources for a plurality of relationship instances each associated with one or more respective domains of a plurality of domains. For each relationship instance of the plurality of relationship instances: the system electronically identifies a rate to calculate an amount of resource due to one or more respective domains associated with the relationship instance based on a source of a resource received for the relationship instance and the one or more respective domains and calculates an amount of resources due to at least one respective domain associated with the relationship instance based on the identified rate. For each domain of the plurality of domains, the system aggregates a total amount of resources due to the domain based on the calculated amount of resources due for each relationship instance associated with the domain.

Abstract: The present invention relates to RNAi constructs for reducing expression of the HSD17B13 gene. Methods of using such RNAi constructs to treat or prevent liver disease, nonalcoholic fatty liver disease (NAFLD) are also described.

Abstract: Systems and methods electronically obtain data regarding a plurality of sources and corresponding amounts of resources received from the sources for a plurality of relationship instances each associated with one or more respective domains of a plurality of domains. For each relationship instance of the plurality of relationship instances: the system electronically identifies a rate to calculate an amount of resource due to one or more respective domains associated with the relationship instance based on a source of a resource received for the relationship instance and the one or more respective domains and calculates an amount of resources due to at least one respective domain associated with the relationship instance based on the identified rate. For each domain of the plurality of domains, the system aggregates a total amount of resources due to the domain based on the calculated amount of resources due for each relationship instance associated with the domain.

Abstract: An apparatus (10) for lifting and moving an object that is underwater. The apparatus including a first (12) and a second (14) chamber, both chambers containing a first (16) and a second (18) fluid. There is a conduit (20, 21) in fluid communication with the first and second chambers, the first and second fluids moveable between the first and second chambers.

Abstract: A conveying device for conveying crop material from a pick-up mechanism to a baler comprises a conveying channel having a base comprising an upstream base part and a downstream base part. The downstream end of the upstream base part is supported on a pair of first resilient mounting members and the upstream end of the downstream base part is supported on a pair of second resilient support members. The first and second resilient support members, in response to the force with which crop material is being urged by the feed rotor against the upstream and downstream base parts exceeding respective first and second predefined values, yield. This results in downward displacement of the upstream base part and the downstream base part to permit crop material to pass through the conveying channel.

Abstract: Features are disclosed for an end effector for automated identification and handling of an object. The end effector includes an entangling structure that can be positioned over an entanglement point of an overpackage in which a desired object is location using sensors. Using the location information, the end effector can identify a path to the entanglement location and detect whether the overpackage is engaged by detecting environmental changes at the end effector.

Abstract: An adhesive formulation is provided that is a waterborne bonding adhesive for adhering sheet membranes that may incorporate a solid plasticizer. The formulation is fast-curing and develops bond strength rapidly after application to a substrate as the adhesive dries, when the sheet membrane is mated to the substrate. The fast-curing characteristic is important to ensure the membrane is not displaced from the surface in windy exterior applications. The adhesive is formulated to form the bond between sheet membranes to substrates that illustratively include, steel, wood, concrete, roof boards, insulation, and fiberglass mat roof boards.

Abstract: The present invention relates to frameworks and methodologies configured to enable support and delivery of a multimedia messaging interface, including (but not limited to) automated content generation and classification, content search and prioritisation, and data analytics. Some embodiments relate to frameworks and methodologies configured to enable generation of and management of content items, which are optionally made available via a messaging interface, via media artefact identification (for example based on contextual data, audio, text and/or object recognition). Examples include technology that enables automated generation and categorisation of sub-clips from one or more media source files.

Abstract: A diagnostic imaging system retrieves data (206) from a plurality of accessible data sources, the accessible data sources storing data including physiological data describing a subject to be imaged, a nature of a requested diagnostic image, image preferences of a clinician who requested the diagnostic image, and previously reconstructed images of the requested nature of the subject and/or other subjects, reconstruction parameters and/or sub-routines used to reconstruct the previously reconstructed images. The system analyzes (6, 12) the retrieved data to automatically generate reconstruction parameters and/or sub-steps specific to the nature of the requested diagnostic image, the subject, and the clinician image preferences. The system controls a display device (10, 216) to display the generated reconstruction parameters and/or sub-routines to the user for a user selection.

Abstract: An imaging system for an optical element, the imaging system comprising means for illuminating a targeted optical element with at least one incident light beam and means for directing at least two light beams returning from at least one surface of the illuminated optical element onto a detector; the detector adapted to measure relative light characteristics of the at least two returning light beams and to calculate at least one parameter of the optical element using the measured characteristics of the at least two returning light beams.

Abstract: The permeability of barrier layers formed from sodium bentonite clay may be significantly and unpredictably impacted upon contacting various ionic substances. Modifying agents may be admixed with sodium bentonite clay to lessen the impacts resulting from its contact with an ionic substance. Suitable modifying agents may comprise an anionic substance selected from the group consisting of a diutan, a polymer containing a 2-acrylamido-2-methylpropanesulfonic acid monomer, any salt thereof, and any combination thereof. Methods for forming a barrier layer may comprise: providing a barrier material comprising sodium bentonite clay and a modifying agent admixed with the sodium bentonite clay, the modifying agent comprising an anionic substance selected from the group consisting of a diutan, a polymer containing a 2-acrylamido-2-methylpropanesulfonic acid monomer, any salt thereof, and any combination thereof; and forming a barrier layer comprising the barrier material.