Patents by Inventor Patrick Curmi

Patrick Curmi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10591486
    Abstract: A method for detecting an interaction between one or more protein bait and one or more candidate prey in a eukaryotic cell, comprising the steps of: a) providing an eukaryotic cell expressing (i) one or more protein bait, and (ii) one or more candidate prey, wherein said protein bait comprises a bait moiety and a polymerized-tubulin binding moiety. b) determining the occurence of an interaction between said one or more protein bait and said one or more candidate prey in the eukaryotic cell, wherein said protein bait is bound to polymerized tubulin in the eukaryotic cell, thereby localizing said one or more candidate prey along said polymerized tubulin, thereby detecting said interaction.
    Type: Grant
    Filed: July 21, 2015
    Date of Patent: March 17, 2020
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE D'EVRY — VAL D-ESSONNE
    Inventors: David Pastre, Michel Cailleret, Patrick Curmi, Mirela Boca
  • Publication number: 20170242026
    Abstract: A method for detecting an interaction between one or more protein bait and one or more candidate prey in a eukaryotic cell, comprising the steps of: a) providing an eukaryotic cell expressing (i) one or more protein bait, and (ii) one or more candidate prey, wherein said protein bait comprises a bait moiety and a polymerized-tubulin binding moiety. b) determining the occurence of an interaction between said one or more protein bait and said one or more candidate prey in the eukaryotic cell, wherein said protein bait is bound to polymerized tubulin in the eukaryotic cell, thereby localizing said one or more candidate prey along said polymerized tubulin, thereby detecting said interaction.
    Type: Application
    Filed: July 21, 2015
    Publication date: August 24, 2017
    Inventors: David PASTRE, Michel CAILLERET, Patrick CURMI, Mirela BOCA
  • Publication number: 20150104804
    Abstract: A method for manufacturing cubic diamond nanocrystals (10) comprising the following successive steps: (a) providing crystalline diamond powder where the maximum particle size of the powder is equal or more than 2 ?m and equal or less than 1 mm; (b) milling said crystalline micron diamond powder using nitrogen jet milling micronization so as to manufacture a fine powder; (c) nanomilling the fine powder of step b) using a planetary tungsten carbide ball mill; (d) acid treating the nanomilled powder of step c); (e) extracting the cubic diamond nanocrystals (10) by centrifugation. Advantageously round-shaped cubic diamond nanocrystals are manufactured.
    Type: Application
    Filed: December 18, 2014
    Publication date: April 16, 2015
    Inventors: Patrick Curmi, Jean-Paul Boudou, Alain Thorel, Fedor Jelezko, Mohamed Sennour
  • Patent number: 8932553
    Abstract: A method for manufacturing cubic diamond nanocrystals (10) comprising the following successive steps: (a) providing crystalline diamond powder where the maximum particle size of the powder is equal or more than 2 um and equal or less than 1 mm; (b) milling said crystalline micron diamond powder using nitrogen jet milling micronization so as to manufacture a fine powder; (c) nanomilling the fine powder of step b) using a planetary tungsten carbide ball mill; (d) acid treating the nanomilled powder of step c); (e) extracting the cubic diamond nanocrystals (10) by centrifugation. Advantageously round-shaped cubic diamond nanocrystals are manufactured.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: January 13, 2015
    Assignees: Institut National de la Sante et de la Recherche Medical (INSERM), Armines, Universitaet Stuttgart, Centre National de la Recherche Scientifique
    Inventors: Patrick Curmi, Jean-Paul Boudou, Alain Thorel, Fedor Jelezko, Mohamed Sennour
  • Patent number: 8932554
    Abstract: Method to produce diamonds containing Nitrogen-Vacancy centers from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising: —Irradiating (12) said diamonds by an electron beam such that the irradiation dose is comprised between 1017 and 1019 electrons per square centimeter; —annealing (14) the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700° C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: January 13, 2015
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universitat Stuttgart, Armines
    Inventors: Jean-Paul Boudou, Patrick Curmi
  • Publication number: 20140065424
    Abstract: Method to produce diamonds containing Nitrogen-Vacancy centres from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising:—Irradiating (12) said diamonds by an electron beam such that the irradiation dose is comprised between 1017 and 1019 electrons per square centimeter;—annealing (14) the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700° C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 6, 2014
    Applicant: INSERM (Institut National de al Santa et de la Recherche Medicale)
    Inventors: Jean-Paul Boudou, Patrick Curmi
  • Patent number: 8574536
    Abstract: Method to produce diamonds containing Nitrogen-Vacancy centers from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising: —Irradiating (12) said diamonds by an electron beam such that the irradiation dose is comprised between 1017 and 1019 electrons per square centimeter; —annealing (14) the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700° C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV.
    Type: Grant
    Filed: May 7, 2008
    Date of Patent: November 5, 2013
    Assignee: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Jean-Paul Boudou, Patrick Curmi
  • Publication number: 20120022231
    Abstract: A method for manufacturing cubic diamond nanocrystals (10) comprising the following successive steps: (a) providing crystalline diamond powder where the maximum particle size of the powder is equal or more than 2 um and equal or less than 1 mm; (b) milling said crystalline micron diamond powder using nitrogen jet milling micronization so as to manufacture a fine powder; (c) nanomilling the fine powder of step b) using a planetary tungsten carbide ball mill; (d) acid treating the nanomilled powder of step c); (e) extracting the cubic diamond nanocrystals (10) by centrifugation. Advantageously round-shaped cubic diamond nanocrystals are manufactured.
    Type: Application
    Filed: March 8, 2010
    Publication date: January 26, 2012
    Inventors: Patrick Curmi, Jean-Paul Boudou, Alain Thorel, Fedor Jelezko, Mohamed Sennour
  • Publication number: 20100135890
    Abstract: Method to produce diamonds containing Nitrogen-Vacancy centres from diamonds grown by a high pressure and high temperature process and containing isolated substitutional nitrogen, comprising: —Irradiating (12) said diamonds by an electron beam such that the irradiation dose is comprised between 1017 and 1019 electrons per square centimeter; —annealing (14) the irradiated diamonds in vacuum or in a inert atmosphere at a temperature above 700° C. and for at least 1 hour; characterized in that said electron beam has an acceleration energy above 7 MeV.
    Type: Application
    Filed: May 7, 2008
    Publication date: June 3, 2010
    Applicant: Inserm(Institut National de la Sante et de la Recherche Medicale)
    Inventors: Jean-Paul Boudou, Patrick Curmi