Patents by Inventor Patrick D. Lopath

Patrick D. Lopath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9339616
    Abstract: Dry powder inhalers include electronic displays, readers and/or counters that can decrement dose amounts, inhibit misuse, read data on drug containment devices and/or communicate with remote devices. The dry powder containers can include at least a pair of cooperating generally tubular members, including an inner member and a generally tubular outer member sized and configured to slidably receive the inner member.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: May 17, 2016
    Assignee: Oriel Therapeutics, Inc.
    Inventors: John Denny, Michael King, Patrick D. Lopath, Jeffrey Alan Warden
  • Patent number: 9027551
    Abstract: Inhalers with fins that deagglomerate dry powder using inspiratory effort of a user of an inhaler. The inhaler fins, at least in steady state conditions, are configured to generate dry powder and airflow patterns having turbulence with flow vortices, some of which may have a vortex having an axis of rotation that extends in an inspiratory flow direction while others may have a vortex that is substantially orthogonal to the inspiratory flow direction in an inspiratory airflow path, as an amount of dry powder travels through the inhaler to thereby deagglomerate the dry powder without trapping undue amounts of the dry powder during inhalation.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: May 12, 2015
    Assignee: Oriel Therapeutics, Inc.
    Inventors: Michael King, Jeffrey Alan Warden, Patrick D. Lopath, Richard D. LaRoche
  • Patent number: 8365725
    Abstract: The disclosure describes methods and inhalers that deagglomerate dry powder using inspiratory effort of a user of an inhaler. Inhaler fin and mesh configurations are described that facilitate deagglomeration. At least in steady state conditions, a dry powder and airflow pattern can be generated having turbulence with flow vortices, some of which may have a vortex having an axis of rotation that extends in an inspiratory flow direction while others may have a vortex that is substantially orthogonal to the inspiratory flow direction in an inspiratory airflow path, as an amount of dry powder travels through the inhaler to thereby deagglomerate the dry powder without trapping undue amounts of the dry powder during inhalation.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: February 5, 2013
    Assignee: Oriel Therapeutics, Inc.
    Inventors: Michael King, Jeffrey Alan Warden, Patrick D. Lopath, Richard D. LaRoche
  • Publication number: 20120255548
    Abstract: Dry powder inhalers include electronic displays, readers and/or counters that can decrement dose amounts, inhibit misuse, read data on drug containment devices and/or communicate with remote devices. The dry powder containers can include at least a pair of cooperating generally tubular members, including an inner member and a generally tubular outer member sized and configured to slidably receive the inner member.
    Type: Application
    Filed: June 6, 2012
    Publication date: October 11, 2012
    Inventors: John Denny, Michael King, Patrick D. Lopath, Jeffrey Alan Warden
  • Patent number: 8210171
    Abstract: Pharmaceutical dry powder containers adapted for use in an inhaler and associated inhalers and kits thereof include at least a pair of cooperating generally tubular members, including an inner member and a generally tubular outer member sized and configured to slidably receive the inner member. In operation, at least one of the inner or outer members slide relative to the other to release a pharmaceutical dry powder.
    Type: Grant
    Filed: September 12, 2005
    Date of Patent: July 3, 2012
    Assignee: Oriel Therapeutics, Inc.
    Inventors: John Denny, Michael King, Patrick D. Lopath, Jeffrey Alan Warden
  • Publication number: 20080168987
    Abstract: Pharmaceutical dry powder containers adapted for use in an inhaler and associated inhalers and kits thereof include at least a pair of cooperating generally tubular members, including an inner member and a generally tubular outer member sized and configured to slidably receive the inner member. In operation, at least one of the inner or outer members slide relative to the other to release a pharmaceutical dry powder.
    Type: Application
    Filed: September 12, 2005
    Publication date: July 17, 2008
    Inventors: John Denny, Michael King, Patrick D. Lopath, Jeffrey Alan Warden
  • Publication number: 20080127971
    Abstract: The disclosure describes methods and inhalers that deagglomerate dry powder using inspiratory effort of a user of an inhaler. Inhaler fin and mesh configurations are described that facilitate deagglomeration. At least in steady state conditions, a dry powder and airflow pattern can be generated having turbulence with flow vortices, some of which may have a vortex having an axis of rotation that extends in an inspiratory flow direction while others may have a vortex that is substantially orthogonal to the inspiratory flow direction in an inspiratory airflow path, as an amount of dry powder travels through the inhaler to thereby deagglomerate the dry powder without trapping undue amounts of the dry powder during inhalation.
    Type: Application
    Filed: September 12, 2005
    Publication date: June 5, 2008
    Inventors: Michael King, Jeffrey Alan Warden, Patrick D. Lopath, Richard D. LaRoche
  • Patent number: 5998910
    Abstract: <001>oriented crystals of lead zinc niobate--lead titanate solid solution (0 to 5 mole % lead titanate) have high electromechanical coupling>85% and exhibit electric field induced phase transition at electric field levels>10.times.Ec (where Ec is the coercive field), resulting in increased transducer driving voltages, decreased fabrication degradation, and high sensitivity/large bandwidth transducer characteristics due to high electromechanical couplings, up to 92%. <001>oriented crystals of lead magnesium niobate--lead titanate solid solution (20 to 50 mole % lead titanate) also exhibit high electromechanical couplings>85% and up to 94%, and thereby can be formed into transducers which exhibit both high sensitivity and large bandwidth.
    Type: Grant
    Filed: January 27, 1998
    Date of Patent: December 7, 1999
    Assignee: The Penn State Research Foundation
    Inventors: Seung-Eek Park, Thomas R. Shrout, Patrick D. Lopath