Patents by Inventor Patrick D. Youso

Patrick D. Youso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Complexes of small-interfering nucleic acids
    Patent number: 9089610
    Abstract: The present invention relates to complexes of small-interfering nucleic acids (siNA). Compositions of siNA suited for administration to a patient are described. Methods for delivering the compositions are also described.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: July 28, 2015
    Assignee: Nektar Therapeutics
    Inventors: Samuel P. McManus, Timothy A. Riley, Sean M. Culbertson, Antoni Kozlowski, Dennis G. Fry, Patrick D. Youso
  • Monoconjugated chitosans as delivery agents for small interfering nucleic acids
    Patent number: 8916693
    Abstract: Conjugates are provided, an exemplary conjugating having a single water-soluble, non-peptidic polymer, such as a poly(ethylene oxide), attached to a chitosan. Complexes of small interfering nucleic acids formed with such conjugates as well as small interfering nucleic acids attached to such conjugates are also provided. Related methods, intermediates, and compositions are also provided.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: December 23, 2014
    Assignee: Nektar Therapeutics
    Inventors: Samuel P. McManus, Antoni Kozlowski, Patrick D. Youso
  • Monoconjugated Chitosans as Delivery Agents for Small Interfering Nucleic Acids
    Publication number: 20120238735
    Abstract: Conjugates are provided, an exemplary conjugating having a single water-soluble, non-peptidic polymer, such as a poly(ethylene oxide), attached to a chitosan. Complexes of small interfering nucleic acids formed with such conjugates as well as small interfering nucleic acids attached to such conjugates are also provided. Related methods, intermediates, and compositions are also provided.
    Type: Application
    Filed: September 16, 2010
    Publication date: September 20, 2012
    Applicant: Nektar Therapeutics
    Inventors: Samuel P. McManus, Antoni Kozlowski, Patrick D. Youso
  • Biomaterials and a method for making and using same
    Patent number: 8252771
    Abstract: A biomaterial is disclosed having unique properties that make it useful in ocular drug delivery applications, where the drugs selected from the group consisting of a prostaglandin, a prostamide, a non-steroidal anti-inflammatory drug (NSAID), and a corticosteroid, and mixtures, derivatives, salts and esters thereof.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: August 28, 2012
    Assignee: Allergan, Inc.
    Inventors: Ronald E. Utecht, Kaia L. Kloster, Therese M. Downey, Barbara R. Haberer, Patrick D. Youso, James N. Chang
  • Complexes of Small-Interfering Nucleic Acids
    Publication number: 20110213013
    Abstract: The present invention relates to complexes of small-interfering nucleic acids (siNA). Compositions of siNA suited for administration to a patient are described. Methods for delivering the compositions are also described.
    Type: Application
    Filed: August 19, 2009
    Publication date: September 1, 2011
    Applicant: Nektar Therapeutics
    Inventors: Samuel P. McManus, Timothy A. Riley, Sean M. Culbertson, Antoni Kozlowski, Dennis G. Fry, Patrick D. Youso
  • NOVEL BIOMATERIALS AND A METHOD FOR MAKING AND USING SAME
    Publication number: 20080207561
    Abstract: A novel biomaterial is disclosed having unique properties that make it useful in ocular drug delivery applications, where the drugs selected from the group consisting of a prostaglandin, a prostamide, a non-steroidal anti-inflammatory drug (NSAID), and a corticosteroid, and mixtures, derivatives, salts and esters thereof.
    Type: Application
    Filed: January 31, 2008
    Publication date: August 28, 2008
    Inventors: Ronald E. Utecht, Kaia L. Kloster, Therese M. Downey, Barbara R. Haberer, Patrick D. Youso, James N. Chang