Patents by Inventor Patrick Dansette

Patrick Dansette has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant cytochrome P450 2B6 proteins and uses thereof
    Patent number: 9243231
    Abstract: The present invention to relates mutant human cytochrome P450 2B6 (CYP2B6) proteins, and fusion proteins comprising said mutant CYP2B6 proteins. In particular, fusion proteins comprising mutant CYP2B6 and NAPDH-cytochrome P450 reductase are provided. The invention also relates to methods of treatment of cancer and the use of said proteins and fusion proteins in the treatment of cancer, in particular via virus-directed enzyme prodrug therapy.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: January 26, 2016
    Assignee: Institut National de la Santé et de la Recherche Médicale (INSERM)
    Inventors: Isabelle De Waziers, Walid Touati, Monique Diry, Jean-Pierre Flinois, Patrick Dansette, Philippe Beaune
  • MUTANT CYTOCHROME P450 2B6 PROTEINS AND USES THEREOF
    Publication number: 20140127180
    Abstract: The present invention to relates mutant human cytochrome P450 2B6 (CYP2B6) proteins, and fusion proteins comprising said mutant CYP2B6 proteins. In particular, fusion proteins comprising mutant CYP2B6 and NAPDH-cytochrome P450 reductase are provided. The invention also relates to methods of treatment of cancer and the use of said proteins and fusion proteins in the treatment of cancer, in particular via virus-directed enzyme prodrug therapy.
    Type: Application
    Filed: May 4, 2012
    Publication date: May 8, 2014
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Isabelle De Waziers, Walid Touati, Monique Diry, Jean-Pierre Flinois, Patrick Dansette, Philippe Beaune
  • 1,2-dithiol-3-thion-S-oxide compounds and pharmaceutical compositions
    Patent number: 5096920
    Abstract: The use of 5-phenyl-3H-1,2-dithiol-3-thion-S-oxides which are optionally substituted in the phenyl ring as active substances in hepato-protective medicaments and new 5-phenyl-3H-1,2-dithiol-3-thion-S-oxides which are substituted in the phenyl ring are described.
    Type: Grant
    Filed: May 26, 1989
    Date of Patent: March 17, 1992
    Assignee: Kali-Chemie Pharma GmbH
    Inventors: Dominique Biard, Marie-Odile Christen, Patrick Dansette, Daniel Jasserand, Daniel Mansuy, Amor Sassi